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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">hepato</journal-id><journal-title-group><journal-title xml:lang="ru">Анналы хирургической гепатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5464</issn><issn pub-type="epub">2408-9524</issn><publisher><publisher-name>НЭИКОН ИСП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.16931/1995-5464.2023-3-75-85</article-id><article-id custom-type="elpub" pub-id-type="custom">hepato-1003</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Спонтанная перфорация в системе желчных протоков</article-title><trans-title-group xml:lang="en"><trans-title>Spontaneous perforation in the bile duct system</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4556-4913</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сигуа</surname><given-names>Б. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sigua</surname><given-names>B. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сигуа Бадри Валериевич – доктор медицинских наук, руководитель центра клинической онкологии ФГБОУ ВО “СЗГМУ  им. И.И. Мечникова” Минздрава России.</p><p>195067, Санкт-Петербург, пр. Пискаревский, д. 47</p><p>Тел.: +7-911-197-93-43</p></bio><bio xml:lang="en"><p>Badri V. Sigua – Doct. of Sci. (Med.), Head of the Clinical Oncology Center, I.I. Mechnikov North-Western State Medical University.</p><p>47, Piskarevsky Ave., Saint Petersburg, 195067</p><p>Phone: +7-911-197-93-43</p></bio><email xlink:type="simple">dr.sigua@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9932-810X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ракита</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Rakita</surname><given-names>S. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ракита Сергей Юрьевич – клинический ординатор кафедры факультетской хирургии им. И.И. Грекова ФГБОУ ВО “СЗГМУ им. И.И. Мечникова” Минздрава России.</p><p>195067, Санкт-Петербург, пр. Пискаревский, д. 47</p></bio><bio xml:lang="en"><p>Sergey Y. Rakita – Resident, Grekov Department of Faculty Surgery, I.I. Mechnikov North-Western State Medical University.</p><p>47, Piskarevsky Ave., Saint Petersburg, 195067</p></bio><email xlink:type="simple">21rs@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7612-1795</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рудь</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Rud</surname><given-names>V. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рудь Вячеслав Юрьевич – клинический ординатор кафедры факультетской хирургии им. И.И. Грекова ФГБОУ ВО “СЗГМУ им. И.И. Мечникова” Минздрава России.</p><p>195067, Санкт-Петербург, пр. Пискаревский, д. 47</p></bio><bio xml:lang="en"><p>Vyacheslav Y. Rud – Resident, Grekov Department of Faculty Surgery, I.I. Mechnikov North-Western State Medical University.</p><p>47, Piskarevsky Ave., Saint Petersburg, 195067</p></bio><email xlink:type="simple">vyacheslavrud27@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4989-5362</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимофеева</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Timofeeva</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимофеева Елена Георгиевна – соискатель кафедры факультетской хирургии им. И.И. Грекова ФГБОУ ВО “СЗГМУ им. И.И. Мечникова” Минздрава России; врач-хирург ООО “Онкологический научный центр”.</p><p>195067, Санкт-Петербург, пр. Пискаревский, д. 47</p></bio><bio xml:lang="en"><p>Elena G. Timofeeva – External Postgraduate Student, Grekov Department of Faculty Surgery, I.I. Mechnikov North-Western State Medical University; Surgeon, LLC “Oncological Research Center”.</p><p>47, Piskarevsky Ave., Saint Petersburg, 195067</p></bio><email xlink:type="simple">timofeevaelenageo@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2329-0023</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Земляной</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Zemlyanoy</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Земляной Вячеслав Петрович – доктор медицинских наук, заведующий кафедрой факультетской хирургии им. И.И. Грекова ФГБОУ ВО “СЗГМУ им. И.И. Мечникова” Минздрава России.</p><p>195067, Санкт-Петербург, пр. Пискаревский, д. 47</p></bio><bio xml:lang="en"><p>Vyacheslav P. Zemlyanoy – Doct. of Sci. (Med.), Head of the Grekov Department of Faculty Surgery, I.I. Mechnikov North-Western State Medical University.</p><p>47, Piskarevsky Ave., Saint Petersburg, 195067</p></bio><email xlink:type="simple">zeml.spb@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО “Северо-Западный государственный медицинский университет им. И.И. Мечникова” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.I. Mechnikov North-Western State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>21</day><month>09</month><year>2023</year></pub-date><volume>28</volume><issue>3</issue><fpage>75</fpage><lpage>85</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сигуа Б.В., Ракита С.Ю., Рудь В.Ю., Тимофеева Е.Г., Земляной В.П., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Сигуа Б.В., Ракита С.Ю., Рудь В.Ю., Тимофеева Е.Г., Земляной В.П.</copyright-holder><copyright-holder xml:lang="en">Sigua B.V., Rakita S.Y., Rud V.Y., Timofeeva E.G., Zemlyanoy V.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hepato.elpub.ru/jour/article/view/1003">https://hepato.elpub.ru/jour/article/view/1003</self-uri><abstract><sec><title>Цель</title><p>Цель. Оценка различных лечебно-диагностических подходов при спонтанной перфорации желчных протоков.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Сообщения о спонтанных перфорациях в системе желчных протоков, опубликованные с 01.01.2000 по 01.06.2022, были отобраны структурированным поиском в базе PubMed/Medline.</p></sec><sec><title>Результаты</title><p>Результаты. По результатам систематического поиска в исследование было включено 58 публикаций, содержащих сведения о 71 пациенте. Наиболее частые симптомы заболевания – боль в животе (92,9%), лихорадка (39,4%), желтуха (33%). Предварительный диагноз был правильно установлен 52,1% больных. Чаще всего развитие заболевания было связано с холедохолитиазом (38%). Перфорация желчных протоков левой доли печени выявлена в 40,6% наблюдений, перфорация общего желчного протока – в 35,5%. У 42,2% больных перфорация желчных протоков привела к развитию перитонита, у 30,9% – к формированию скопления желчи или абсцессу. Подкапсульное и внутрипеченочное скопление желчи обнаружено в 18,3% наблюдений. Лечение при перфорациях с развитием подкапсульного и внутрипеченочного скопления желчи осуществляли комбинированно, применяли чрескожное чреспеченочное дренирование и эндоскопические методы. Перфорация желчных протоков с развитием распространенных форм заболевания требовала двухэтапного лечения. На первом этапе выполняли санацию брюшной полости, декомпрессию билиарного тракта. На втором этапе устраняли причину перфорации, выполняли резекционно-реконструктивное оперативное вмешательство. Летальность составила 5,6%.</p></sec><sec><title>Заключение</title><p>Заключение. Спонтанная перфорация в системе желчных протоков – редкое патологическое состояние, являющееся осложнением заболеваний органов гепатопанкреатодуоденальной зоны. Оно требует повышенной осведомленности от абдоминальных хирургов. Основа хирургической стратегии – правильно установленный диагноз и поэтапная тактика лечения, что позволяет уменьшить частоту осложнений и летальность.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To evaluate different therapeutic and diagnostic approaches in spontaneous bile duct perforation.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The present study involved the reports on spontaneous perforations in the bile duct system, published from 01.01.2000 to 01.06.2022 and selected by structured search in PubMed/Medline database.</p></sec><sec><title>Results</title><p>Results. As a result, 58 articles describing 71 patients were selected for the study. The most frequent symptoms of the disease included abdominal pain (92.9%), fever (39.4%), and jaundice (33%). The provisional diagnosis was made correctly in 52.1% of cases. The development of the disease was most often associated with choledocholithiasis (38%). Bile ducts perforation of the left hepatic lobe was revealed in 40.6% of cases, perforation of the common bile duct – in 35.5%. Bile duct perforation resulted in peritonitis in 42.2% of patients and bile accumulation or abscess in 30.9%. Encapsulated and intrahepatic accumulation of bile was found in 18.3% of cases. Management of perforations with development of encapsulated and intrahepatic bile accumulation included combined treatment, embracing percutaneous transhepatic drainage and endoscopic methods. Perforation of bile ducts with development of extensive forms of the disease required two-stage treatment. The first stage involved lavage of the abdominal cavity and decompression of the biliary tract. The second stage involved resective and reconstructive surgery to eliminate the cause of the perforation. The mortality rate was 5.6%.</p></sec><sec><title>Conclusion</title><p>Conclusion. Spontaneous perforation in the bile duct system is a rare pathological state appeared as a complication of hepatopancreaticoduodenal diseases. Its management requires greater awareness of abdominal surgeons. The surgical strategy is based on correctly diagnosed and staged treatment tactics, which allows the incidence of complications and mortality rate to be reduced.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>печень</kwd><kwd>разрыв желчных протоков</kwd><kwd>спонтанная перфорация</kwd><kwd>гепатобилиарная хирургия</kwd><kwd>экстренная хирургия</kwd><kwd>скопление желчи</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver</kwd><kwd>bile duct rupture</kwd><kwd>spontaneous perforation</kwd><kwd>hepatobiliary surgery</kwd><kwd>emergency surgery</kwd><kwd>bile accumulation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Masroor M., Sarwari M.A. Spontaneous common bile duct perforation in full term pregnancy: a rare case report and review of literature. 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