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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">hepato</journal-id><journal-title-group><journal-title xml:lang="ru">Анналы хирургической гепатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5464</issn><issn pub-type="epub">2408-9524</issn><publisher><publisher-name>НЭИКОН ИСП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.16931/1995-5464.2023-3-56-64</article-id><article-id custom-type="elpub" pub-id-type="custom">hepato-1041</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЖЕЛЧНЫЕ ПУТИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BILE DUCTS</subject></subj-group></article-categories><title-group><article-title>Прижизненная неинвазивная оценка деструктивных изменений желчного пузыря и тяжести острого холецистита</article-title><trans-title-group xml:lang="en"><trans-title>Non-invasive assessment of destructive changes in the gallbladder and severity of acute cholecystitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6664-1308</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимербулатов</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Timerbulatov</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимербулатов Махмуд Вилевич – доктор медицинских наук, профессор, заведующий кафедрой факультетской хирургии ФГБОУ ВО “Башкирский ГМУ” Минздрава России.</p><p>450008, Уфа, ул. Ленина, д. 3</p></bio><bio xml:lang="en"><p>Mahmud V. Timerbulatov – Doct. of Sci. (Med.), Professor, Head of the Faculty Surgery Department of the Bashkir State Medical University.</p><p>3, Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">timerm@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-6343-1295</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ямалов</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yamalov</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ямалов Рустам Азатович – кандидат медицинских наук, ассистент кафедры хирургии с курсом эндоскопии ФГБОУ ВО “Башкирский ГМУ” Минздрава России.</p><p>450008, Уфа, ул. Ленина, д. 3</p></bio><bio xml:lang="en"><p>Rustam A. Yamalov – Cand. of Sci. (Med.), Assistant, Department of Surgery with the Course of Endoscopy of the Bashkir State Medical University.</p><p>3, Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">bsmp92@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4832-6363</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимербулатов</surname><given-names>Ш. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Timerbulatov</surname><given-names>Sh. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимербулатов Шамиль Вилевич – доктор медицинских наук, профессор кафедры хирургии с курсом эндоскопии ФГБОУ ВО “Башкирский ГМУ” Минздрава России.</p><p>450008, Уфа, ул. Ленина, д. 3</p></bio><bio xml:lang="en"><p>Shamil V. Timerbulatov – Doct. of Sci. (Med.), Professor, Department of Surgery with the Course of Endoscopy of the Bashkir State Medical University.</p><p>3, Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">timersh@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4489-4678</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Какауллина</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kakaullina</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Какауллина Люция Назифовна – кандидат медицинских наук, доцент кафедры лучевой диагностики ФГБОУ ВО “Башкирский ГМУ” Минздрава России.</p><p>450008, Уфа, ул. Ленина, д. 3</p></bio><bio xml:lang="en"><p>Lucia N. Kakaullina – Cand. of Sci. (Med.), Associate Professor, Diagnostic Radiology Department of the Bashkir State Medical University.</p><p>3, Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">kakaulina_ln@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1485-8457</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарипов</surname><given-names>Р. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Garipov</surname><given-names>R. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гарипов Рим Мухаррямович – доктор медицинских наук, профессор кафедры хирургии с курсом эндоскопии ФГБОУ ВО “Башкирский ГМУ” Минздрава России.</p><p>450008, Уфа, ул. Ленина, д. 3</p></bio><bio xml:lang="en"><p>Rim M. Garipov – Doct. of Sci. (Med.), Professor of the Department of Surgery with the Course of Endoscopy of the Bashkir State Medical University.</p><p>3, Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">rimgaripoff@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2874-7213</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гафарова Айгуль Радиковна – ассистент кафедры хирургии с курсом эндоскопии ФГБОУ ВО “Башкирский ГМУ” Минздрава России.</p><p>450008, Уфа, ул. Ленина, д. 3</p><p>Тел.: +7-937-303-58-88</p></bio><bio xml:lang="en"><p>Aigul R. Gafarova – Аssistant of the Department of Surgery with the Course of Endoscopy of the Bashkir State Medical University.</p><p>3, Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">argafarova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1696-3146</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимербулатов</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Timerbulatov</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимербулатов Виль Мамилович – доктор медицинских наук, профессор, член-корреспондент РАН, заведующий кафедрой хирургии с курсом эндоскопии ФГБОУ ВО “Башкирский ГМУ” Минздрава России.</p><p>450008, Уфа, ул. Ленина, д. 3</p></bio><bio xml:lang="en"><p>Vil M. Timerbulatov – Doct. of Sci. (Med.), Professor, Corresponding Member of the Russian Academy of Sciences, Head of the Department of Surgery with the Course of Endoscopy of the Bashkir State Medical University.</p><p>3, Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">timervil@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1996-4830</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гараев</surname><given-names>Р. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Garaev</surname><given-names>R. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гараев Руслан Ралифович – ассистент кафедры хирургии с курсом эндоскопии ФГБОУ ВО “Башкирский ГМУ” Минздрава России.</p><p>450008, Уфа, ул. Ленина, д. 3</p></bio><bio xml:lang="en"><p>Ruslan R. Garaev – Assistant of the Department of Surgery with the Course of Endoscopy of the Bashkir State Medical University.</p><p>3, Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">garaev.r.r@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО “Башкирский государственный медицинский университет” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>21</day><month>09</month><year>2023</year></pub-date><volume>28</volume><issue>3</issue><fpage>56</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тимербулатов М.В., Ямалов Р.А., Тимербулатов Ш.В., Какауллина Л.Н., Гарипов Р.М., Гафарова А.Р., Тимербулатов В.М., Гараев Р.Р., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Тимербулатов М.В., Ямалов Р.А., Тимербулатов Ш.В., Какауллина Л.Н., Гарипов Р.М., Гафарова А.Р., Тимербулатов В.М., Гараев Р.Р.</copyright-holder><copyright-holder xml:lang="en">Timerbulatov M.V., Yamalov R.A., Timerbulatov S.V., Kakaullina L.N., Garipov R.M., Gafarova A.R., Timerbulatov V.M., Garaev R.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hepato.elpub.ru/jour/article/view/1041">https://hepato.elpub.ru/jour/article/view/1041</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучить возможности УЗИ в оценке патоморфологических изменений стенки желчного пузыря по критериям А1 и А2 и тяжести острого холецистита по шкалам G1–G3.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Анализировали результаты обследования и лечения 556 больных острым холециститом за последние 2 года. Рассматривали данные клинико-лабораторных исследований и УЗИ, их совпадение с результатами гистологического исследования удаленного желчного пузыря.</p></sec><sec><title>Результаты</title><p>Результаты. Совпадение клинико-лабораторных данных с патогистологическими данными при G1 было  в 84,9% наблюдений, G2 – в 74,5%, G3 – в 63,2%, совпадение результатов УЗИ с патогистологическими данными при А1 отмечено в 81,54% наблюдений, при А2 – в 86,59%. Частота послеоперационных осложнений при G1 составила 4,6%, при G2 – 8,4%, при G3 – 32,1%, при А1 – 6,8% и А2 – 27,7%. Летальные исходы были только в группе пациентов G3 (3,77%) и А2 (2,12%), общая послеоперационная летальность составила 0,42%, частота послеоперационных осложнений – 10,94%.</p></sec><sec><title>Заключение</title><p>Заключение. УЗИ у 86,6% больных острым холециститом позволяет оценить патоморфологические изменения стенки желчного пузыря, что существенно облегчает принятие решения о сроках и объеме хирургического вмешательства.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the potential of ultrasound examination for assessment of pathomorphological changes in the gallbladder wall according to A1 and A2 criteria and severity of acute cholecystitis (G1-G3 score).</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The authors analyzed the results of examination and treatment of 556 patients with acute cholecystitis for the last 2 years. The study involved clinical, laboratory and ultrasound results, their coincidence with the results of histological examination of the removed gallbladder.</p></sec><sec><title>Results</title><p>Results. Clinical and laboratory data coincided with histopathological data in G1 in 84.9% of cases, G2 – in 74.5%, G3 – in 63.2%; ultrasound findings coincided with histopathological data in A1 in 81.54% of cases, in A2 – in 86.59%. The incidence of postoperative complications in G1 comprised 4.6%, in G2 – 8.4%, in G3 – 32.1%, in A1 – 6.8%, and in A2 – 27.7%. Fatal outcomes appeared only in G3 (3.77%) and A2 (2.12%) patients, the overall postoperative mortality was 0.42% and the incidence of postoperative complications was 10.94%.</p></sec><sec><title>Conclusion</title><p>Conclusion. Ultrasound examination in 86.6% of patients with acute cholecystitis enables pathomorphological changes in the gallbladder wall to be evaluated, which significantly facilitates decision making about the timing and extent of surgical intervention.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>желчный пузырь</kwd><kwd>острый холецистит</kwd><kwd>УЗИ</kwd><kwd>тяжесть заболевания</kwd><kwd>сроки холецистэктомии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gallbladder</kwd><kwd>acute cholecystitis</kwd><kwd>ultrasound</kwd><kwd>severity of disease</kwd><kwd>timing of cholecystectomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бебуришвили А.Г., Панин С.И., Зюбина Е.Н., Нестеров С.С., Пузикова А.В. Холецистостомия при остром холецистите. Хирургия. Журнал им. Н.И. 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