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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">hepato</journal-id><journal-title-group><journal-title xml:lang="ru">Анналы хирургической гепатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5464</issn><issn pub-type="epub">2408-9524</issn><publisher><publisher-name>НЭИКОН ИСП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.16931/31/1995-5464.2024-3-100-107</article-id><article-id custom-type="elpub" pub-id-type="custom">hepato-1132</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЕЛЕЗЕНКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SPLEEN</subject></subj-group></article-categories><title-group><article-title>Морфологическое обоснование хирургического лечения пациентов с истинной аневризмой селезеночной артерии</article-title><trans-title-group xml:lang="en"><trans-title>Morphological rationale for surgical treatment of patients with true splenic artery aneurysm</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4230-8033</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабунин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shabunin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шабунин Алексей Васильевич – доктор мед. наук, профессор, академик РАН, заведующий кафедрой хирургии; главный врач</p><p>125993, Москва, ул. Баррикадная, д. 2/1, стр. 1</p><p>125284, Москва, 2-й Боткинский пр-д, д. 5</p></bio><bio xml:lang="en"><p>Aleksey V. Shabunin – Doct. of Sci. (Med.), Professor, Academician of the Russian Academy of Sciences, Head of Department of Surgery; Chief Medical Officer</p><p>2/1 bld. 1, Barrikadnaya str., Moscow, 125993</p><p>5, 2-nd Botkinsky pr., Moscow, 125284</p></bio><email xlink:type="simple">glavbotkin@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5699-3695</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Багателия</surname><given-names>З. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bagateliya</surname><given-names>Z. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Багателия Зураб Антонович – доктор мед. наук, профессор кафедры хирургии; заместитель главного врача по медицинской части</p><p>125993, Москва, ул. Баррикадная, д. 2/1, стр. 1</p><p>125284, Москва, 2-й Боткинский пр-д, д. 5</p></bio><bio xml:lang="en"><p>Zurab A. Bagateliya – Doct. of Sci. (Med.), Professor, Department of Surgery; Deputy Chief Medical Officer</p><p>2/1 bld. 1, Barrikadnaya str., Moscow, 125993</p><p>5, 2-nd Botkinsky pr., Moscow, 125284</p></bio><email xlink:type="simple">bagateliaz@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8441-6561</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бедин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bedin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бедин Владимир Владимирович – доктор мед. наук, профессор кафедры хирургии; заместитель главного врача по хирургии</p><p>125993, Москва, ул. Баррикадная, д. 2/1, стр. 1</p><p>125284, Москва, 2-й Боткинский пр-д, д. 5</p></bio><bio xml:lang="en"><p>Vladimir V. Bedin – Doct. of Sci. (Med.), Professor, Department of Surgery; Chief of Surgical Department</p><p>2/1 bld. 1, Barrikadnaya str., Moscow, 125993</p><p>5, 2-nd Botkinsky pr., Moscow, 125284</p></bio><email xlink:type="simple">bedinvv@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0335-1204</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тавобилов</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tavobilov</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тавобилов Михаил Михайлович – доктор мед. наук, профессор кафедры хирургии; заведующий отделением гепатопанкреатобилиарной хирургии</p><p>125993, Москва, ул. Баррикадная, д. 2/1, стр. 1</p><p>125284, Москва, 2-й Боткинский пр-д, д. 5</p></bio><bio xml:lang="en"><p>Mikhail M. Tavobilov – Doct. of Sci. (Med.), Professor, Department of Surgery; Head of Department of Liver and Pancreas Surgery</p><p>2/1 bld. 1, Barrikadnaya str., Moscow, 125993</p><p>5, 2-nd Botkinsky pr., Moscow, 125284</p></bio><email xlink:type="simple">botkintmm@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5142-1302</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карпов Алексей Андреевич – доктор мед. наук, ассистент кафедры хирургии; хирургии ФГБОУ ДПО РМАНПО Минздрава России</p><p>125993, Москва, ул. Баррикадная, д. 2/1, стр. 1</p><p>125284, Москва, 2-й Боткинский пр-д, д. 5</p></bio><bio xml:lang="en"><p>Аleksey A. Karpov – Doct. of Sci. (Med.), Assistant, Department of Surgery; Surgeon, Department of Liver and Pancreas Surgery</p><p>2/1 bld. 1, Barrikadnaya str., Moscow, 125993</p><p>5, 2-nd Botkinsky pr., Moscow, 125284</p></bio><email xlink:type="simple">botkin.karpov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8278-7147</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиева</surname><given-names>Ф. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Alieva</surname><given-names>F. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алиева Фариза Файзуллоевна – аспирант кафедры хирургии; врач-хирург</p><p>125993, Москва, ул. Баррикадная, д. 2/1, стр. 1</p><p>125284, Москва, 2-й Боткинский пр-д, д. 5</p></bio><bio xml:lang="en"><p>Fariza F. Alieva – Graduate-student, Department of Surgery; Surgeon</p><p>2/1 bld. 1, Barrikadnaya str., Moscow, 125993</p><p>5, 2-nd Botkinsky pr., Moscow, 125284</p></bio><email xlink:type="simple">alievafariza@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4021-9085</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гордиенко</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gordienko</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гордиенко Елена Николаевна – канд. мед. наук, младший научный сотрудник, врач-патологоанатом отделения патологической анатомии</p><p>125993, Москва, ул. Баррикадная, д. 2/1, стр. 1</p></bio><bio xml:lang="en"><p>Elena N. Gordienko – Cand. of Sci. (Med.), Junior Researcher, Pathologist, Pathology Unit</p><p>2/1 bld. 1, Barrikadnaya str., Moscow, 125993</p></bio><email xlink:type="simple">gordienko119@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ДПО “Российская медицинская академия непрерывного профессионального образования” Минздрава России; ГБУЗ “Московский многопрофильный научно-клинический центр им. С.П. Боткина” Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation, Department of Surgery; S.P. Botkin City Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ДПО “Российская медицинская академия непрерывного профессионального образования” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation, Department of Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2024</year></pub-date><volume>29</volume><issue>3</issue><fpage>100</fpage><lpage>107</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шабунин А.В., Багателия З.А., Бедин В.В., Тавобилов М.М., Карпов А.А., Алиева Ф.Ф., Гордиенко Е.Н., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Шабунин А.В., Багателия З.А., Бедин В.В., Тавобилов М.М., Карпов А.А., Алиева Ф.Ф., Гордиенко Е.Н.</copyright-holder><copyright-holder xml:lang="en">Shabunin A.V., Bagateliya Z.A., Bedin V.V., Tavobilov M.M., Karpov A.A., Alieva F.F., Gordienko E.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hepato.elpub.ru/jour/article/view/1132">https://hepato.elpub.ru/jour/article/view/1132</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучить морфологические особенности строения стенки аневризмы селезеночной артерии с целью выявления наиболее безопасного и эффективного метода хирургического лечения.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. С 2020 по 2023 г. оперировали 43 пациента с истинной аневризмой селезеночной артерии. Применяли лапароскопическое клипирование ветвей аневризмы, лапароскопическую резекцию аневризмы, лапароскопическую спленэктомию, резекцию гигантской аневризмы селезеночной артерии. Проведено клинико-морфологическое исследование 16 макропрепаратов аневризмы селезеночной артерии. Исследованию подвергали стенку аневризмы и прилежащую стенку селезеночной артерии без макроскопических признаков расширения просвета на протяжении 1 см от аневризматического расширения.</p></sec><sec><title>Результаты</title><p>Результаты. Микроскопическое исследование показало наличие фрагментов рыхлой, отечной стенки крупных артерий эластического типа с атеросклерозом, атероматозом и кальцификацией. В интиме наблюдали атероматозные бляшки; отложение кальция выявили в 81,25% препаратов, дефекты эластических волокон – во всех препаратах. Эластическая мембрана была истончена или имела прерывистую структуру. Морфологические изменения в стенке селезеночной артерии сохранялись на расстоянии до 1,0 ± 0,2 см проксимальнее и дистальнее аневризмы.</p></sec><sec><title>Заключение</title><p>Заключение. Учитывая выявленные особенности морфологического строения аневризмы, формирование сосудистого анастомоза селезеночной артерии “конец в конец”, клипирование или прошивание шейки аневризмы представляют значительный риск рецидива аневризмы. Лапароскопическое клипирование ветвей аневризмы селезеночной артерии на расстоянии &gt;1,5 см от краев аневризмы становится операцией выбора для больных этой категории.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the morphological features of the wall structure of the splenic artery aneurysm in order to identify the safest and most effective method of surgical treatment.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. From 2020 to 2023, 43 patients underwent surgery for true splenic artery aneurysm. Interventions involved laparoscopic clipping of aneurysm branches, laparoscopic resection of aneurysm, laparoscopic splenectomy, and resection of giant splenic artery aneurysm. A clinical and morphological study of 16 slides of splenic artery aneurysm was performed. The aneurysm wall and the adjacent wall of the splenic artery without macroscopic signs of lumen dilatation for 1 cm from the aneurysmal dilatation were examined.</p></sec><sec><title>Results</title><p>Results. Microscopic study revealed fragments of loose, edematous wall of large elastic arteries with atherosclerosis, atheromatosis and calcification. Atherosclerotic plaques were observed in the intima; calcium deposits were detected in 81.25% of slides, and defects in elastic fibers – in all slides. The elastic membrane was thinned or had a discontinuous structure. Morphological changes in the wall of the splenic artery persisted up to 1.0 ± 0.2 cm proximal and distal to the aneurysm.</p></sec><sec><title>Conclusion</title><p>Conclusion. Taking into account the revealed features of the morphological structure of the aneurysm, the formation of an end-to-end vascular anastomosis of the splenic artery, clipping or suturing of the aneurysm neck pose a significant risk of aneurysm recurrence. Laparoscopic clipping of splenic artery aneurysm branches at a distance of &gt;1.5 cm from the edges of the aneurysm becomes the operation of choice for patients in this category.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>селезеночная артерия</kwd><kwd>аневризма</kwd><kwd>морфологическое исследование</kwd><kwd>лапароскопическая резекция аневризмы</kwd><kwd>спленэктомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>splenic artery</kwd><kwd>aneurysm</kwd><kwd>morphological examination</kwd><kwd>laparoscopic resection of aneurysm</kwd><kwd>splenectomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pandey S.K., Bhattacharya S., Mishra R.N., Shukla V.K. Anatomical variations of the splenic artery and its clinical implications. Clin. 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