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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">hepato</journal-id><journal-title-group><journal-title xml:lang="ru">Анналы хирургической гепатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5464</issn><issn pub-type="epub">2408-9524</issn><publisher><publisher-name>НЭИКОН ИСП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.16931/31/1995-5464.2024-3-50-59</article-id><article-id custom-type="elpub" pub-id-type="custom">hepato-1137</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОСОБЕННОСТИ ГЕПАТОПАНКРЕАТОБИЛИАРНОЙ ХИРУРГИИ У БОЛЬНЫХ ПОЖИЛОГО И СТАРЧЕСКОГО ВОЗРАСТА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SPECIFICS OF HEPATO-PANCREATO-BILIARY SURGERY IN ELDERLY AND SENILE PATIENTS</subject></subj-group></article-categories><title-group><article-title>Способ ликвидации остаточной полости с ригидной фиброзной капсулой при эхинококкозе печени у пациентов с коморбидностью</article-title><trans-title-group xml:lang="en"><trans-title>Method for elimination of residual cavity with rigid fibrous capsule in patients with hepatic echinococcosis and comorbidity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2891-8748</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Назиров</surname><given-names>Ф. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Nazyrov</surname><given-names>F. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Назыров Феруз Гафурович – доктор мед. наук, профессор, академик АН РУз, главный консультант директора</p><p>100115, Ташкент, ул. Кичик Халка Йули, д. 10</p></bio><bio xml:lang="en"><p>Feruz G. Nazyrov – Doct. of Sci. (Med.), Professor, Academician of the Uzbek Academy of Sciences, Сhief Сonsultant to the Director</p><p>10 Kichik Khalka Yuli str., Tashkent, 100115</p></bio><email xlink:type="simple">cs.75@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4403-1859</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабаджанов</surname><given-names>А. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Babadjanov</surname><given-names>A. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бабаджанов Азам Хасанович – доктор мед. наук, профессор, главный научный сотрудник отделения гепатобилиарной хирургии и трансплантации печени №2</p><p>100115, Ташкент, ул. Кичик Халка Йули, д. 10</p></bio><bio xml:lang="en"><p>Azam Kh. Babadjanov – Doct. of Sci. (Med.), Chief Researcher, Department of Hepatobiliary Surgery and Liver Transplantation No. 2</p><p>10 Kichik Khalka Yuli str., Tashkent, 100115</p></bio><email xlink:type="simple">azam746@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7375-3594</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махмудов</surname><given-names>У. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Makhmudov</surname><given-names>U. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Махмудов Улугбек Маруфджанович – доктор мед. наук, старший научный сотрудник отделения гепатобилиарной хирургии и трансплантации печени №2</p><p>100115, Ташкент, ул. Кичик Халка Йули, д. 10</p></bio><bio xml:lang="en"><p>Ulugbek M. Makhmudov – Doct. of Sci. (Med.), Senior Researcher, Department of Hepatobiliary Surgery and Liver Transplantation No. 2</p><p>10 Kichik Khalka Yuli str., Tashkent, 100115</p></bio><email xlink:type="simple">bek-mahmudov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4156-9071</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Туксанов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tuksanov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Туксанов Алишер Искандарович – канд. мед. наук, главный врач медико-санитарного отдела регионального управления “Навои”</p><p>210100, г. Навои, ул. Навои, д. 27</p></bio><bio xml:lang="en"><p>Alisher I. Tuksanov – Cand. of Sci. (Med.), Chief Physician</p><p>210100, Navoi, Navoi str. 27</p></bio><email xlink:type="simple">cs.75@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГУ “Республиканский специализированный научно-практический медицинский центр хирургии им. академика В. Вахидова”</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>The Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov</institution><country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Медико-санитарный отдел регионального управления “Навои”, Государственное учреждение “Фонд” Навоийского горно-металлургического комбината</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Medical and Sanitary Unit, State institution “Fund of Navoi Mining and Metallurgy Company”, State Institution “Fund” of the Navoi Mining and Metallurgical Combine</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2024</year></pub-date><volume>29</volume><issue>3</issue><fpage>50</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Назиров Ф.Г., Бабаджанов А.Х., Махмудов У.М., Туксанов А.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Назиров Ф.Г., Бабаджанов А.Х., Махмудов У.М., Туксанов А.И.</copyright-holder><copyright-holder xml:lang="en">Nazyrov F.G., Babadjanov A.K., Makhmudov U.M., Tuksanov A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hepato.elpub.ru/jour/article/view/1137">https://hepato.elpub.ru/jour/article/view/1137</self-uri><abstract><sec><title>Цель</title><p>Цель. Улучшение результатов органосохраняющих операций при эхинококковых кистах печени с ригидной фиброзной капсулой.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Анализировали результаты хирургического лечения 221 больного эхинококкозом печени с 2016 по 2023 г. В основную группу включено 94 больных (2020–2023), которым после лапаротомной или лапароскопической эхинококкэктомии проводили дополнительную обработку остаточной полости предложенным способом (всего 113 кист). В группу сравнения вошли 88 пациентов (2016–2019), которым вмешательства выполняли стандартно (всего 108 кист).</p></sec><sec><title>Результаты</title><p>Результаты. Состояние фиброзной капсулы определяет возможности выбора метода обработки остаточной полости. При эластичной фиброзной капсуле резекционные вмешательства выполнены 1,7% пациентов в группе сравнения и 1,9% – в основной группе. Доля лапароскопической эхинококкэктомии составила 29,1 и 38,5%, открытой эхинококкэктомии – 69,2 и 59,6%. При ригидной фиброзной капсуле резекционные вмешательства были выполнены 4,3% пациентов в группе сравнения и 8% – в основной группе. Доля лапароскопической эхинококкэктомии оставила 8,5 и 23,9%, открытой эхинококкэктомии – 87,2 и 68,2%.</p></sec><sec><title>Заключение</title><p>Заключение. Применение предложенного способа дополнительной обработки остаточной полости при открытых и лапароскопических вмешательствах позволило уменьшить риск ранних осложнений с 19,1 до 4,5%, а в течение 3 мес после операции – с 16 до 3,4%.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To improve the results of organ-preserving surgeries for hepatic echinococcal cysts with rigid fibrous capsule.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study analyzed the results of surgical treatment of 221 patients with hepatic echinococcosis that was performed from 2016 to 2023. The main group included 94 patients (2020–2023), who underwent laparotomic or laparoscopic echinococcectomy followed by additional treatment of the residual cavity by the suggested method (113 cysts in total). The comparison group included 88 patients (2016–2019) who underwent standard interventions (108 cysts in total).</p></sec><sec><title>Results</title><p>Results. A treatment method for the residual cavity is selected with regard to the condition of the fibrous capsule. In case of elastic fibrous capsule, resections were performed in 1.7% of patients in the comparison group and 1.9% in the main group. Laparoscopic echinococcectomy was performed in 29.1% and 38.5% of cases, open echinococcectomy – in 69.2% and 59.6%, respectively. In case of rigid fibrous capsule, resections were made in 4.3% of patients in the comparison group and in 8% in the main group. Laparoscopic echinococcectomy was performed in 8.5% and 23.9% of cases, open echinococcectomy – in 87.2% and 68.2%, respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. The suggested method of additional treatment for the residual cavity in cases of open and laparoscopic interventions enables the risk of early complications to be reduced from 19.1% to 4.5%, and from 16% to 3.4% within 3 months after surgery.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>эхинококкоз печени</kwd><kwd>фиброзная капсула</kwd><kwd>эхинококкэктомия</kwd><kwd>остаточная полость</kwd><kwd>лазерное воздействие</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hepatic echinococcosis</kwd><kwd>fibrous capsule</kwd><kwd>echinococcectomy</kwd><kwd>residual cavity</kwd><kwd>laser exposure</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Республиканский специализированный научно-практический медицинский центр хирургии имени академика В.Вахидова</funding-statement><funding-statement xml:lang="en">State Institution "Republican Specialized Scientific and Practical Medical Center of Surgery named after academician V.Vakhidov"</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шевченко, Ю.Л. Хирургия эхинококкоза: монография / Ю.Л. Шевченко, Ф.Г. Назыров. – М.: Династия, 2016. 288с.</mixed-citation><mixed-citation xml:lang="en">Shevchenko Y.L., Nazyrov F.G. Khirurgiya ekhinokokkoza: monografiya [Surgery of echinococcosis: monograph]. Moscow: Dinastiya, 2016. 288 p. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Brunetti E, Kern P, Vuitton DA. 2010. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop 114:1–16. doi:10.1016/j.actatropica.2009.11.001.</mixed-citation><mixed-citation xml:lang="en">Brunetti E, Kern P, Vuitton DA. 2010. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop 114:1–16. doi:10.1016/j.actatropica.2009.11.001.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Bastid C, Terraz S, Toso C, Chappuis F, Spahr L, Bresson-Hadni S. Actualités sur l’échinococcose kystique hépatique [Update on cystic echinococcosis of the liver]. Rev Med Suisse. 2021 Sep 1;17(748):1466-1473. French. PMID: 34468098.</mixed-citation><mixed-citation xml:lang="en">Bastid C, Terraz S, Toso C, Chappuis F, Spahr L, Bresson-Hadni S. Actualités sur l’échinococcose kystique hépatique [Update on cystic echinococcosis of the liver]. Rev Med Suisse. 2021 Sep 1;17(748):1466-1473. French. PMID: 34468098.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao ZM, Yin ZZ, Meng Y, Jiang N, Ma ZG, Pan LC, Tan XL, Chen X, Liu R. Successful robotic radical resection of hepatic echinococcosis located in posterosuperior liver segments. World J Gastroenterol 2020; 26(21): 2831-2838.</mixed-citation><mixed-citation xml:lang="en">Zhao ZM, Yin ZZ, Meng Y, Jiang N, Ma ZG, Pan LC, Tan XL, Chen X, Liu R. Successful robotic radical resection of hepatic echinococcosis located in posterosuperior liver segments. World J Gastroenterol 2020; 26(21): 2831-2838.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Jaén-Torrejimeno I, López-Guerra D, Rojas-Holguín A, De-Armas-Conde N, Blanco-Fernández G. Surgical treatment of liver hydatid cyst in elderly patients: A propensity score-matching retrospective cohort study. Acta Trop. 2022 Aug;232:106466. doi: 10.1016/j.actatropica.2022.106466.</mixed-citation><mixed-citation xml:lang="en">Jaén-Torrejimeno I, López-Guerra D, Rojas-Holguín A, De-Armas-Conde N, Blanco-Fernández G. Surgical treatment of liver hydatid cyst in elderly patients: A propensity score-matching retrospective cohort study. Acta Trop. 2022 Aug;232:106466. doi: 10.1016/j.actatropica.2022.106466.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Baraket O., Moussa M., Ayed K., Kort B., Bouchoucha S. Predictive factors of morbidity after surgical treatment of hydatid cyst of the liver // Arab J. Gastroenterol., 15 (2014), pp. 119-122, 10.1016/j.ajg.2014.05.004.</mixed-citation><mixed-citation xml:lang="en">Baraket O., Moussa M., Ayed K., Kort B., Bouchoucha S. Predictive factors of morbidity after surgical treatment of hydatid cyst of the liver // Arab J. Gastroenterol., 15 (2014), pp. 119-122, 10.1016/j.ajg.2014.05.004.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bockhorn M., Sotiropoulos G.C., Sgourakis G., Neuhaus J.P., Molmenti E.P., Lang H., Frilling A., Broelsch C.E. Major liver resections in the elderly - Is an aggressive approach justified? // Int. J. Colorectal Dis., 24 (2009), pp. 83-86, 10.1007/s00384-008-0571-4.</mixed-citation><mixed-citation xml:lang="en">Bockhorn M., Sotiropoulos G.C., Sgourakis G., Neuhaus J.P., Molmenti E.P., Lang H., Frilling A., Broelsch C.E. Major liver resections in the elderly - Is an aggressive approach justified? // Int. J. Colorectal Dis., 24 (2009), pp. 83-86, 10.1007/s00384-008-0571-4.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Cho S.W., Steel J., Tsung A., Marsh J.W., Geller D.A., Gamblin T.C. Safety of liver resection in the elderly–How important is age? // Ann. Surg. Oncol., 18 (2011), pp. 1088-1095, 10.1245/s10434-010-1404-6.</mixed-citation><mixed-citation xml:lang="en">Cho S.W., Steel J., Tsung A., Marsh J.W., Geller D.A., Gamblin T.C. Safety of liver resection in the elderly–How important is age? // Ann. Surg. Oncol., 18 (2011), pp. 1088-1095, 10.1245/s10434-010-1404-6.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kumari S., Semira C., Lee M., Lee B., Wong R., Nott L., Shapiro J., Gibbs P. Resection of colorectal cancer liver metastases in older patients // ANZ J. Surg., 90 (2020), pp. 796-801, 10.1111/ans.15750.</mixed-citation><mixed-citation xml:lang="en">Kumari S., Semira C., Lee M., Lee B., Wong R., Nott L., Shapiro J., Gibbs P. Resection of colorectal cancer liver metastases in older patients // ANZ J. Surg., 90 (2020), pp. 796-801, 10.1111/ans.15750.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
