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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">hepato</journal-id><journal-title-group><journal-title xml:lang="ru">Анналы хирургической гепатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5464</issn><issn pub-type="epub">2408-9524</issn><publisher><publisher-name>НЭИКОН ИСП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.16931/1995-5464.2016211-24</article-id><article-id custom-type="elpub" pub-id-type="custom">hepato-141</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕЗЕКЦИЯ ПЕЧЕНИ В УСЛОВИЯХ ЦЕНТРА ТРАНСПЛАНТОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LIVER RESECTION IN TRANSPLANTATION CENTER</subject></subj-group></article-categories><title-group><article-title>ТРАНСПЛАНТАЦИИ И РАДИКАЛЬНЫЕ РЕЗЕКЦИИ ПЕЧЕНИ С РЕКОНСТРУКЦИЯМИ СОСУДОВ ПРИ РАСПРОСТРАНЕННОМ АЛЬВЕОКОККОЗЕ</article-title><trans-title-group xml:lang="en"><trans-title>LIVER TRANSPLANTATION AND LIVER RESECTION WITH VASCULAR RECONSTRUCTION FOR ADVANCED ALVEOCOCCOSIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поршенников</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Porshennikov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Поршенников Иван Анатольевич — канд. мед. наук, заместитель главного врача по хирургической помощи ГБУЗ НСО “ГНОКБ”; доцент кафедры госпитальной и детской хирургии ГБОУ ВПО НГМУ Минздрава РФ </p><p>Для корреспонденции: Поршенников Иван Анатольевич —630087, г. Новосибирск, ул. Немировича-Данченко, д. 130</p></bio><bio xml:lang="en"><p>Porshennikov Ivan Anatolievich — Cand. of Med. Sci., Deputy Chief Physician for Surgical Care, State Novosibirsk Regional Clinical Hospital; Assistant Professor at the Chair of Hospital and Pediatric Surgery, Novosibirsk State Medical University </p><p>For correspondence: Porshennikov Ivan Anatolievich — 130, Nemirovicha-Danchenko str., Novosibirsk, 630087, Russian Federation</p></bio><email xlink:type="simple">porshennikov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быков</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Bykov</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлик</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlik</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карташов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kartashov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щёкина</surname><given-names>Е. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchekina</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юшина</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Korobeynikova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коробейникова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yushina</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ НСО “Государственная Новосибирская областная клиническая больница"; &#13;
ГБОУ ВПО “Новосибирский государственный медицинский университет” Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Novosibirsk Regional Clinical Hospital; &#13;
Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ НСО “Государственная Новосибирская областная клиническая больница"</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Novosibirsk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ НСО “Государственная Новосибирская областная клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Novosibirsk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>21</day><month>02</month><year>2018</year></pub-date><volume>21</volume><issue>2</issue><fpage>11</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Поршенников И.А., Быков А.Ю., Павлик В.Н., Карташов А.С., Щёкина Е.Е., Юшина Е.Г., Коробейникова М.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Поршенников И.А., Быков А.Ю., Павлик В.Н., Карташов А.С., Щёкина Е.Е., Юшина Е.Г., Коробейникова М.А.</copyright-holder><copyright-holder xml:lang="en">Porshennikov I.A., Bykov A.Y., Pavlik V.N., Kartashov A.S., Shchekina E.E., Korobeynikova M.A., Yushina E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hepato.elpub.ru/jour/article/view/141">https://hepato.elpub.ru/jour/article/view/141</self-uri><abstract><sec><title>Цель</title><p>Цель: изучить результаты трансплантаций и радикальных резекций печени с реконструкцией сосудов при распространенном альвеококкозе.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В ретроспективное исследование включен 21 пациент с альвекококкозом с поражением более 5 сегментов печени и (или) паразитарной инвазией в бифуркацию воротной вены, и (или) в нижнюю полую вену, и (или) в гепатикокавальный конфлюэнс.</p></sec><sec><title>Результаты</title><p>Результаты. Резекцию печени выполнили 9 (42,9%) пациентам (группа 1) при наличии технической возможности сохранения или реконструкции афферентного и (или) эфферентного венозного русла остающейся части печени. Гипотермическую перфузию in vivo in situ применили в 1 наблюдении, реконструкцию воротной вены выполнили в 5 наблюдениях, реконструкцию нижней полой вены — в 8, реконструкцию артерии — в 1. Трансплантацию выполнили 12 (57,1%) пациентам (группа 2): у 6 больных был цирроз печени, у 1 — синдром Бадда—Киари. Целая печень от посмертных доноров трансплантирована 7 реципиентам, 5 больным — правая половина печени от живых родственных доноров. Резекция нижней полой вены выполнена в 10 наблюдениях. Госпитальной летальности не было. При медиане наблюдения 17 мес не отмечено рецидива заболевания. Общая однолетняя и трехлетняя выживаемость составила 100 и 89% соответственно (p = 0,617).</p></sec><sec><title>Заключение</title><p>Заключение. Радикальное лечение при распространенном альвеококкозе печени осуществимо у подавляющего большинства пациентов при отсутствии нерезектабельных отдаленных метастазов и исходно корректном выборе хирургической тактики. Операции необходимо выполнять в специализированных центрах, рутинно выполняющих резекции и трансплантации.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the results of liver transplantations and resections with vascular reconstruction for advanced alveococcosis.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. The retrospective study included 21 patients with alveococcosis and lesion of more than 5 segments and (or) a parasitic invasion into portal vein bifurcation and (or) inferior vena cava, and (or) hepaticocaval confluence.</p></sec><sec><title>Results</title><p>Results. Liver resection was performed in 9 (42.9%) patients (group 1) if preserving or reconstruction of afferent and (or) efferent venous bed of remaining liver part was technically feasible. Hypothermic perfusion in vivo in situ was used in 1 case, portal vein reconstruction — in 5 cases, inferior vena cava reconstruction — in 8 patients, arterial reconstruction — in 1 patient. Transplantation was performed in 12 (57.1%) patients (group 2). There were 6 patients with liver cirrhosis and 1 patient with Budd-Chiari syndrome. The whole liver from postmortem donors was transplanted to 7 recipients, right liver half from living related donors — to 5 patients. Inferior vena cava resection was performed in 10 cases. Hospital mortality was absent. Median recurrence-free follow-up was 17 months. Overall 1- and 3-year survival was 100% and 89%, respectively (p = 0.617).</p></sec><sec><title>Conclusion</title><p>Conclusion. Radical treatment of advanced liver alveococcosis is feasible in the most of patients if unresectable distant metastases are absent and initial surgical tactics is correct. Interventions should be performed in specialized centers where resections and transplantations are routinely performed.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>печень</kwd><kwd>альвеококкоз</kwd><kwd>резекция</kwd><kwd>гипотермическая перфузия</kwd><kwd>трансплантация печени</kwd><kwd>реконструкция сосудов</kwd></kwd-group><kwd-group xml:lang="en"><kwd>alveococcosis</kwd><kwd>resection</kwd><kwd>hypothermic perfusion</kwd><kwd>liver transplantation</kwd><kwd>vascular reconstruction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Virchow R. Die multiloculare, ulcerirende Echinokokk- engeschwulst der Leber. Verhandlungen der Physicalisch- Medicinischen Gesellschaft. 1855; 84—95.</mixed-citation><mixed-citation xml:lang="en">Virchow R. Die multiloculare, ulcerirende Echinokokk- engeschwulst der Leber. 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