<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">hepato</journal-id><journal-title-group><journal-title xml:lang="ru">Анналы хирургической гепатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5464</issn><issn pub-type="epub">2408-9524</issn><publisher><publisher-name>НЭИКОН ИСП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.16931/1995-5464.2016256-61</article-id><article-id custom-type="elpub" pub-id-type="custom">hepato-146</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕЧЕНЬ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LIVER</subject></subj-group></article-categories><title-group><article-title>НОВЫЙ СПОСОБ РАССЕЧЕНИЯ ПАРЕНХИМЫ ПЕЧЕНИ ПРИ РЕЗЕКЦИИ</article-title><trans-title-group xml:lang="en"><trans-title>NEW METHOD OF LIVER PARENCHYMA DISSECTION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахаладзе</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhaladze</surname><given-names>G. G.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гребенкин</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Grebenkin</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гребенкин Егор Николаевич — канд. мед. наук, научный сотрудник отдела хирургии и хирургических технологий в онкологии </p><p>Для корреспонденции: Гребенкин Егор Николаевич — 141090, Московская область, г. Королев, ул. Тихомировой, 10-26</p></bio><bio xml:lang="en"><p>Grebenkin Egor Nikolaevich — Cand. of Med. Sci., Researcher of Research Department of Surgery and Surgical Technologies in Oncology </p><p>For correspondence: Grebenkin Egor Nikolaevich — 10-26, Korolev, Tikhomirovoy str., 141090, Russian Federation</p></bio><email xlink:type="simple">genbytu@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ “Российский научный центр рентгенорадиологии”Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Research Center of Roentgenoradiology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>22</day><month>02</month><year>2018</year></pub-date><volume>21</volume><issue>2</issue><fpage>56</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ахаладзе Г.Г., Гребенкин Е.Н., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Ахаладзе Г.Г., Гребенкин Е.Н.</copyright-holder><copyright-holder xml:lang="en">Akhaladze G.G., Grebenkin E.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hepato.elpub.ru/jour/article/view/146">https://hepato.elpub.ru/jour/article/view/146</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучить эффективность разработанного метода, заключающегося в раздавливании паренхимы печени зажимом, подключенным к генератору тока высокой частоты, с одновременной ирригацией линии рассечения физиологическим раствором.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Исследовали результаты 40 резекций печени, разделенных на 3 группы. В основную группу включены 15 резекций, выполненных разработанным методом. Первую контрольную группу составили 18 резекций, выполненных при помощи биполярной коагуляции, вторую группу — 7 резекций, выполненных гармоническим скальпелем.</p></sec><sec><title>Результаты</title><p>Результаты. Кровопотеря в исследуемой группе составила 627,01 ± 161,89 мл, в группе коагуляции — 811 ± 225,09 мл, в группе гармонического скальпеля — 1652,29 ± 624,51 мл (p = 0,008). Продолжительность операции в исследуемой группе составила 301,67 ± 26,08 мин, в группе коагуляции — 360,15 ± 29,32 мин, в группе гармонического скальпеля — 386,14 ± 40,41 мин. Достоверных различий в результатах получено не было (p = 0,104).</p></sec><sec><title>Заключение</title><p>Заключение. Разработанный метод диссекции позволяет достоверно уменьшить величину кровопотери без выполнения портальной окклюзии и несколько сократить время вмешательства. Сокращение кровопотери, даже при пересечении большого объема паренхимы, позволяет более широко применять сегмент-ориентиро- ванные резекции печени, особенно мезогепатэктомию, увеличивая контингент операбельных пациентов и приводя к улучшению результатов лечения пациентов с опухолями печени в целом.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the effectiveness of the developed method consisting of crushing of liver parenchyma by clamp connected to high-frequency generator with simultaneous irrigation of dissection line with sodium chloride solution.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. We investigated the results of 40 liver resections which were divided into 3 groups. The study group included 15 resections performed by original method. The first control group consisted of 18 resections by bipolar coagulation, the second group consisted of 7 resections by harmonic scalpel.</p></sec><sec><title>Results</title><p>Results. Blood loss was 627.011 ± 161.894 ml, 811 ml ± 225.088 and 1652.29 ± 624.507 ml in all groups respectively. The average duration of surgery was 301.67 ± 26.084 minutes in study group, 360.15 ± 29.316 minutes in the group of coagulation and 386.14 ± 40.409 minutes in the harmonic scalpel group. There were no significant differences in results (p = 0.104).</p></sec><sec><title>Conclusion</title><p>Conclusion. The original method reduces the level of blood loss without portal occlusion and duration of surgery in some degree. Reduced blood loss allows to perform widely segmental hepatectomy even in case of advanced intersection of parenchyma (for example mesohepatectomy), to expand the sample of operable patients and to improve outcomes.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>печень</kwd><kwd>резекция</kwd><kwd>рассечение паренхимы</kwd><kwd>диссекция</kwd><kwd>опухоль печени</kwd><kwd>метастазы печени</kwd><kwd>сегмент- ориентированная резекция</kwd><kwd>мезогепатэктомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver</kwd><kwd>resection</kwd><kwd>intersection of parenchyma</kwd><kwd>dissection</kwd><kwd>liver cancer</kwd><kwd>liver metastases</kwd><kwd>segmental hepatectomy</kwd><kwd>mesohepatectomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">von Heesen M., Schuld J., Sperling J., Grunhage F., Lammert F., Richter S., Schilling M.K., Kollmar O. Parenchyma-preserving hepatic resection for colorectal liver metastases. Langenbecks Arc. Surg. 2012; 397 (3): 383-395. doi: 10.1007/s00423-011-0872-x.</mixed-citation><mixed-citation xml:lang="en">von Heesen M., Schuld J., Sperling J., Grunhage F., Lammert F., Richter S., Schilling M.K., Kollmar O. Parenchyma-preserving hepatic resection for colorectal liver metastases. Langenbecks Arc. Surg. 2012; 397 (3): 383-395. doi: 10.1007/s00423-011-0872-x.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Gurusamy K.S., Pamecha V., Sharma D., Davidson B.R. Techniques for liver parenchymal transection in liver resection. Cochrane Database Syst. Rev. 2009; 21 (1): CD006880. doi: 10.1002/14651858.CD006880.pub2.</mixed-citation><mixed-citation xml:lang="en">Gurusamy K.S., Pamecha V., Sharma D., Davidson B.R. Techniques for liver parenchymal transection in liver resection. Cochrane Database Syst. Rev. 2009; 21 (1): CD006880. doi: 10.1002/14651858.CD006880.pub2.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Lee S.Y. Central hepatectomy for centrally located malignant liver tumors: A systematic review. World J. Hepatol. 2014; 6 (5): 347-357. doi: 10.4254/wjh.v6.i5.347.</mixed-citation><mixed-citation xml:lang="en">Lee S.Y. Central hepatectomy for centrally located malignant liver tumors: A systematic review. World J. Hepatol. 2014; 6 (5): 347-357. doi: 10.4254/wjh.v6.i5.347.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Lin T.Y. A simplified technique for hepatic resection: the crush method. Ann. Surg. 1974; 180 (3): 285-290.</mixed-citation><mixed-citation xml:lang="en">Lin T.Y. A simplified technique for hepatic resection: the crush method. Ann. Surg. 1974; 180 (3): 285-290.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Tung T.T. Veineuse du Foie et se Applications aux Resections Hepatiques. Hanoi; 1939.</mixed-citation><mixed-citation xml:lang="en">Tung T.T. Veineuse du Foie et se Applications aux Resections Hepatiques. Hanoi; 1939.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Edward C.S., Sheung T.F., Chung-Mau L. Hepatic resection for hepatocellular carcinoma. Ann. Surg. 1955, 22 (3): 291-298.</mixed-citation><mixed-citation xml:lang="en">Edward C.S., Sheung T.F., Chung-Mau L. Hepatic resection for hepatocellular carcinoma. Ann. Surg. 1955, 22 (3): 291-298.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C., Wong J. Hepatectomy for hepatoceflular carcinoma: Toward zero hospital deaths. Ann. Surg. 1999; 229 (3): 322-330.</mixed-citation><mixed-citation xml:lang="en">Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C., Wong J. Hepatectomy for hepatoceflular carcinoma: Toward zero hospital deaths. Ann. Surg. 1999; 229 (3): 322-330.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Arnoieili J.P, Brodsky J. Reduction of transfusion requirments during major hepatic resection for metastatic disease. Surgery. 1999; 125 (2): 166-173.</mixed-citation><mixed-citation xml:lang="en">Arnoieili J.P, Brodsky J. Reduction of transfusion requirments during major hepatic resection for metastatic disease. Surgery. 1999; 125 (2): 166-173.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Guo R., Feng X., Xiao S., Yan J., Xia F., Ma K., Li X. Short- and long-term outcomes of hepatectomy with or without radiofrequency-assist for the treatment of hepatocellular carcinomas: a retrospective comparative cohort study. Biosci. Trends. 2015; 9 (1): 65-72. doi: 10.5582/bst.2014.01142.</mixed-citation><mixed-citation xml:lang="en">Guo R., Feng X., Xiao S., Yan J., Xia F., Ma K., Li X. Short- and long-term outcomes of hepatectomy with or without radiofrequency-assist for the treatment of hepatocellular carcinomas: a retrospective comparative cohort study. Biosci. Trends. 2015; 9 (1): 65-72. doi: 10.5582/bst.2014.01142.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hanyong S., Wanyee L., Siyuan F.A. Prospective randomized controlled trial: comparison of two different methods of hepatectomy. Eur. J. Surg. Oncol. 2015; 41 (2): 243-248. doi: 10.1016/j.ejso.2014.10.057.</mixed-citation><mixed-citation xml:lang="en">Hanyong S., Wanyee L., Siyuan F.A. Prospective randomized controlled trial: comparison of two different methods of hepatectomy. Eur. J. Surg. Oncol. 2015; 41 (2): 243-248. doi: 10.1016/j.ejso.2014.10.057.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Guo J.Y., Li D.W., Liao R., Huang P., Kong X.B., Wang J.M., Wang H.L., Luo S.Q., Yan X., Du C.Y. Outcomes of simple saline-coupled bipolar electrocautery for hepatic resection. World J.Gastroenterol. 2014; 20 (26): 8638-8645. doi: 10.3748/wjg.v20.i26.8638.</mixed-citation><mixed-citation xml:lang="en">Guo J.Y., Li D.W., Liao R., Huang P., Kong X.B., Wang J.M., Wang H.L., Luo S.Q., Yan X., Du C.Y. Outcomes of simple saline-coupled bipolar electrocautery for hepatic resection. World J.Gastroenterol. 2014; 20 (26): 8638-8645. doi: 10.3748/wjg.v20.i26.8638.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Инструмент для коагуляции и резекции паренхиматозных тканей: патент 153859 МПК А61В 17/00 (2006/01)/ Г.Г. Ахаладзе, Е.Н. Гребенкин, В.Н. Макаров, В.И. Мирошник, В.А. Солодкий, В.П. Харченко. Заявитель и патентообладатель Закрытое акционерное общество Фирма “ТЕХНОСВЕТ” №2014141730/14, заявл. 16.10.2014, опубл. 10.08.2015, Бюл. №22, 2 стр. Instrument dlya koagulyatsii i rezektsii parenkhimatoznykh tkanej: patent 153859 MPK А6ГУ 17/00 (2006/01) [The device for coagulation and resection of parenchymal tissues: Patent 153859 MPK А6ГУ 17/00 (2006/01)]/ G.G. Mhaladze, E. N. Grebenkin, V.N. Makarov, V.I. Miroshnik, УА. Solodkij, V.P. Kharchenko. Zayavitel' i patentoobladatel' Zakrytoe aktsionernoe obshhestvo Firma “TEKHNOSVET” №2014141730/14, zayavl. 16.10.2014, opubl. 10.08.2015, Byul. №22, 2 рр. (In Russian)</mixed-citation><mixed-citation xml:lang="en">Инструмент для коагуляции и резекции паренхиматозных тканей: патент 153859 МПК А61В 17/00 (2006/01)/ Г.Г. Ахаладзе, Е.Н. Гребенкин, В.Н. Макаров, В.И. Мирошник, В.А. Солодкий, В.П. Харченко. Заявитель и патентообладатель Закрытое акционерное общество Фирма “ТЕХНОСВЕТ” №2014141730/14, заявл. 16.10.2014, опубл. 10.08.2015, Бюл. №22, 2 стр. Instrument dlya koagulyatsii i rezektsii parenkhimatoznykh tkanej: patent 153859 MPK А6ГУ 17/00 (2006/01) [The device for coagulation and resection of parenchymal tissues: Patent 153859 MPK А6ГУ 17/00 (2006/01)]/ G.G. Mhaladze, E. N. Grebenkin, V.N. Makarov, V.I. Miroshnik, УА. Solodkij, V.P. Kharchenko. Zayavitel' i patentoobladatel' Zakrytoe aktsionernoe obshhestvo Firma “TEKHNOSVET” №2014141730/14, zayavl. 16.10.2014, opubl. 10.08.2015, Byul. №22, 2 рр. (In Russian)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
