hepatoАнналы хирургической гепатологииAnnaly khirurgicheskoy gepatologii = Annals of HPB Surgery1995-54642408-9524НЭИКОН ИСП10.16931/1995-5464.20152111-118hepato-239Research ArticleКЛИНИЧЕСКОЕ НАБЛЮДЕНИЕCASE REPORTЗондовая конфокальная лазерная эндомикроскопия в диагностике заболеваний желчных протоковConfocal Laser Endomicroscopy in the Diagnosis of Biliary Ducts DiseasesСазоновД. В.SazonovD. V.

канд. мед. наук, руководитель отдела эндоскопии НИИ клинической хирургии ФГБУ ФНКЦ ФМБА России

Cand. of Med. Sci., Head of the Endoscopy Department of Research Institute of Clinical Surgery of Federal State Institution “Federal Research Clinical Centre of Specialized Types of Medical Care and Medical Technologies of the Federal Medical-Biological Agency of Russia”

ПанченковД. Н.PanchenkovD. N.

доктор мед. наук, профессор, заведующий лабораторией минимально инвазивной хирургии ГБОУ ВПО “МГМСУ им. А.И. Евдокимова” Минздрава России

Doct. of Med. Sci., Professor, Head of the Laboratory of Minimally Invasive Surgery, A.I. Evdokimov Moscow State University of Medicine and Dentistry

ИвановЮ. В.IvanovYu. V.

доктор мед. наук, профессор, руководитель отдела абдоминальной и индокринной хирургии, заместитель директора НИИ клинической хирургии ФГБУ ФНКЦ ФМБА России

Doct. of Med. Sci., Professor, Head of the Department of Abdominal and Endocrine Surgery, DeputyDirector of the Research Institute of Clinical Surgery of Federal State Institution “Federal Research Clinical Center ofSpecialized Types of Medical Care and Medical Technologies of the Federal Medical-Biological Agency of Russia”

ivanovkb83@yandex.ruШабловскийО. Р.ShablovskyO. R.

доктор мед. наук, профессор, директор НИИ клинической хирургии ФГБУ ФНКЦ ФМБА России

Doct. of Med. Sci., Professor, Director of the Research Institute of Clinical Surgery of Federal State Institution “Federal Research Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical-Biological Agency of Russia”

ДанилевскаяО. В.DanilevskayaO. V.

канд. мед. наук, старший научный сотрудник отдела эндоскопии НИИ клинической хирургии ФГБУ ФНКЦ ФМБА России

Cand. of Med. Sci., Senior Research Officer of the Endoscopy Department, Research Institute of Clinical Surgery of Federal State Institution “Federal Research Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical-Biological Agency of Russia”

ЛебедевД. П.LebedevD. P.

врач-хирург отделения рентгенохирургических методов диагностики и лечения ФГБУ ФНКЦ ФМБА России

Surgeon of the Department of X-Ray Diagnostic and Treatment Methods, Research Institute of Clinical Surgery of Federal State Institution “Federal Research Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical-Biological Agency of Russia”

АлехновичА. В.AlekhnovichA. V.

канд. мед. наук, докторант кафедры хирургии ФПДО ГБОУ ВПО “МГМСУ им. А.И. Евдокимова” Минздрава России

Surgeon of the Department of X-Ray Diagnostic and Treatment Methods, Research Institute of Clinical Surgery of Federal State Institution “Federal Research Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical-Biological Agency of Russia”

ЗабозлаевФ. Г.ZabozlaevF. G.

доктор мед. наук, профессор, руководитель отдела современных морфологических методов исследования ФГБУ ФНКЦ ФМБА России

Doct. of Med. Sci., Professor, Head of the Department of Modern Morphological Studies, Research Institute of Clinical Surgery of Federal State Institution “Federal Research Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical-Biological Agency of Russia”

Научно-исследовательский институт клинической хирургии ФГБУ “Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий Федерального медико-биологического агентства России”РоссияResearch Institute of Clinical Surgery of Federal State Institution “Federal Research Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical-Biological Agency of Russia”Russian FederationГБОУ ВПО “Московский государственный медико-стоматологический университет им. А.И. Евдокимова” Минздрава РоссииРоссияState-Funded Educational Institution of Higher Professional Education “A.I. Evdokimov Moscow State University of Medicine and Dentistry”Russian FederationНаучно-исследовательский институт клинической хирургии ФГБУ “Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий Федерального медико-биологического агентства России”РоссияFederal State Institution “Federal Research Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical-Biological Agency of Russia”Russian Federation201522032018202111118Copyright © Сазонов Д.В., Панченков Д.Н., Иванов Ю.В., Шабловский О.Р., Данилевская О.В., Лебедев Д.П., Алехнович А.В., Забозлаев Ф.Г., 20182018Сазонов Д.В., Панченков Д.Н., Иванов Ю.В., Шабловский О.Р., Данилевская О.В., Лебедев Д.П., Алехнович А.В., Забозлаев Ф.Г.Sazonov D.V., Panchenkov D.N., Ivanov Y.V., Shablovsky O.R., Danilevskaya O.V., Lebedev D.P., Alekhnovich A.V., Zabozlaev F.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://hepato.elpub.ru/jour/article/view/239

Приведены клинические наблюдения различных заболеваний желчных протоков, в том числе холангиокарциномы, развившихся на фоне хронических заболеваний и стриктур гепатопанкреатодуоденальной зоны. Отражены сложности инструментальной диагностики на ранней стадии заболевания. Впервые при этом заболевании с диагностической целью применен метод зондовой конфокальной лазерной эндомикроскопии, позволивший во всех наблюдениях уточнить и верифицировать диагноз. Описан метод исследования, его результаты сопоставлены с другими методами диагностики. Авторы предполагают, что при диагностике заболеваний органов гепатопанкреатодуоденальной зоны метод зондовой конфокальной лазерной эндомикроскопии может иметь решающее значение при неэффективности или малой информативности других методов.

It is presented the clinical observations of various bile ducts diseases including cholangiocarcinoma developed on background of chronic diseases in pancreato-biliary area. Complexities of instrumental diagnosis at early stage of disease are reflected. Probe confocal laser endomicroscopy was first applied to clarify and verify the diagnosis in all cases. Technique of research is described; its results are compared with other diagnostic methods. The authors suggest that in diagnosis of pancreatic and biliary diseases probe confocal laser endomicroscopy may be crucial in case of inefficient or uninformative other methods

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The authors declare that there are no conflicts of interest present.