hepatoАнналы хирургической гепатологииAnnaly khirurgicheskoy gepatologii = Annals of HPB Surgery1995-54642408-9524НЭИКОН ИСП10.16931/1995-5464.2018454-67hepato-369Research ArticleВОЗМОЖНОСТИ РЕЗЕКЦИОННОЙ ХИРУРГИИ И ТРАНСПЛАНТАЦИИ ПЕЧЕНИ В ЛЕЧЕНИИ ОПУХОЛЕВЫХ И ПАРАЗИТАРНЫХ ЗАБОЛЕВАНИЙPOSSIBILITIES OF RESECTION SURGERY AND LIVER TRANSPLANTATION FOR MALIGNANT AND PARASITIC DISEASESТрансплантация печени при метастатическом колоректальном раке (клиническое наблюдение)Liver transplantation for metastatic colorectal cancer (case report)https://orcid.org/0000-0002-6969-6865ПоршенниковИ. А.PorshennikovI. A.

Поршенников Иван Анатольевич — кандидат медицинских наук, руководитель хирургической службы ГБУЗ НСО “ГНОБ, доцент кафедры госпитальной и детской хирургии НГМУ.

6300087, Новосибирск, ул. Немировича-Данченко, д. 130, тел.: +7-383-315-96-76

ResearcherID: H-6324-2018

SPIN: 7291-7988

Ivan A. Porshennikov — Cand. of Med. Sci., Deputy Chief for Surgical Care SNRCH; Associate Professor of the Chair of Hospital-Based and Pediatric Surgery, NSMU.

130, Nemirovicha-Danchenko str., Novosibirsk, 630087, Phone: +7 (383) 315 96 76

porshennikov@mail.ruСоколовА. В.SokolovA. V.

Соколов Андрей Викторович — заведующий онкологическим отделением №2.

630047, Новосибирск, ул. Залесского, д. 6

Andrey V. Sokolov — Head of the Oncology Department No. 2.

630047, Novosibirsk, 6 Zalesskogo str.

ЩёкинаЕ. Е.ShchekinaE. E.

Щёкина Елена Евгеньевна — врач-хирург отделения трансплантации органов.

6300087, Новосибирск, ул. Немировича-Данченко, д. 130

Elena E. Shchekina — Surgeon of the Organ Transplantation Department.

130 Nemirovicha-Danchenko str, Novosibirsk, 630087

ЧубуковА. Ю.ChubukovA. Yu.

Чубуков Александр Юрьевич — врач-онколог онкологического отделения №2.

630047, Новосибирск, ул. Залесского, д. 6

Aleksandr Yu. Chubukov — Oncologist of the Oncology Department No 2.

630047, Novosibirsk, 6 Zalesskogo str.

ТретьяковаТ. А.TretyakovaT. A.

Третьякова Татьяна Анатольевна — врач-онколог онкологического отделения № 2.

630047, Новосибирск, ул. Залесского, д. 6

Tatyana A. Tretyakova — Oncologist of the Oncology Department No 2.

630047, Novosibirsk, 6 Zalesskogo str.

ОстанинаИ. Б.OstaninaI. B.

Останина Ирина Борисовна — врач-онколог.

630108, Новосибирск, ул. Плахотного, д. 2

Irina B. Ostanina — Oncologist.

630108, Novosibirsk, 2 Plakhotnogo str.

КарташовА. С.KartashovA. S.

Карташов Алексей Сергеевич — врач-хирург отделения трансплантации органов.

6300087, Новосибирск, ул. Немировича-Данченко, д. 130

Aleksey S. Kartashov — Surgeon of the Organ Transplantation Department.

130 Nemirovicha-Danchenko str, Novosibirsk, 630087

КоробейниковаМ. А.KorobeynikovaM. A.

Коробейникова Мария Александровна — врач-хирург отделения трансплантации органов.

6300087, Новосибирск, ул. Немировича-Данченко, д. 130

Mariya A. Korobeynikova — Surgeon of the Organ Transplantation Department.

130 Nemirovicha-Danchenko str, Novosibirsk, 630087

ЮшинаЕ. Г.YushinaE. G.

Юшина Екатерина Геннадьевна — врач-хирург отделения трансплантации органов.

6300087, Новосибирск, ул. Немировича-Данченко, д. 130

Ekaterina G. Yushina — Surgeon of the Organ Transplantation Department.

130 Nemirovicha-Danchenko str, Novosibirsk, 630087

БыковА. Ю.BykovA. Yu.

Быков Александр Юрьевич — заведующий отделением трансплантации органов.

6300087, Новосибирск, ул. Немировича-Данченко, д. 130

Aleksandr Yu. Bykov — Head of the Organ Transplantation Department.

130 Nemirovicha-Danchenko str, Novosibirsk, 630087

ГБУЗ НСО “Государственная Новосибирская областная клиническая больница; ФГБОУВО “Новосибирский государственный медицинский университет” Минздрава РоссииРоссияState Novosibirsk Regional Clinical Hospital; Novosibirsk State Medical University of Ministry of Health of the Russian FederationRussian FederationГБУЗ НСО Городская клиническая больница №1РоссияCity Clinical Hospital No. 1Russian FederationГБУЗ НСО “Государственная Новосибирская областная клиническая больницаРоссияState Novosibirsk Regional Clinical HospitalRussian FederationГБУЗ НСО Городская клиническая больница № 1РоссияCity Clinical Hospital No. 1Russian FederationГБУЗ НСО Новосибирский областной клинический онкологический диспансерRussian FederationNovosibirsk Regional Clinical Oncology CentreRussian Federation2018130120192345467Copyright © Поршенников И.А., Соколов А.В., Щёкина Е.Е., Чубуков А.Ю., Третьякова Т.А., Останина И.Б., Карташов А.С., Коробейникова М.А., Юшина Е.Г., Быков А.Ю., 20192019Поршенников И.А., Соколов А.В., Щёкина Е.Е., Чубуков А.Ю., Третьякова Т.А., Останина И.Б., Карташов А.С., Коробейникова М.А., Юшина Е.Г., Быков А.Ю.Porshennikov I.A., Sokolov A.V., Shchekina E.E., Chubukov A.Y., Tretyakova T.A., Ostanina I.B., Kartashov A.S., Korobeynikova M.A., Yushina E.G., Bykov A.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://hepato.elpub.ru/jour/article/view/369

Трансплантация печени при метастазах колоректального рака является противоречивым лечебным мероприятием и не рекомендована в клинических практических руководствах. В статье представлено первое в России клиническое наблюдение трансплантации печени от посмертного донора молодой пациентке с множественными билобарными нерезектабельными метастазами рака ободочной кишки в печени. Заболевание не прогрессирует в течение 10 мес на фоне иммуносупрессивной терапии (эверолимус) и адъювантного лечения. В кратком литературном обзоре освещено состояние проблемы и место трансплантации печени в лечении метастатического колоректального рака.

Liver transplantation is currently controversial for colorectal cancer metastases and not recommended in clinical guidelines. We report the first Russian case of liver transplantation from cadaveric donor in a patient with multiple bilobar unresectable liver metastases of colon cancer. We observe no recurrences within 10 months on everolimus-based immunosuppression and adjuvant treatment. The current state of the problem and the place of liver transplantation in metastatic colorectal cancer treatment are discussed in a short review.

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The authors declare that there are no conflicts of interest present.