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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">hepato</journal-id><journal-title-group><journal-title xml:lang="ru">Анналы хирургической гепатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5464</issn><issn pub-type="epub">2408-9524</issn><publisher><publisher-name>НЭИКОН ИСП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.16931/1995-5464.20211100-106</article-id><article-id custom-type="elpub" pub-id-type="custom">hepato-646</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПОДЖЕЛУДОЧНАЯ ЖЕЛЕЗА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PANCREAS</subject></subj-group></article-categories><title-group><article-title>Непосредственные результаты дистальной субтотальной резекции поджелудочной железы с сохранением селезенки</article-title><trans-title-group xml:lang="en"><trans-title>Immediate results of spleen-preserving distal subtotal pancreatic resection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1021-4382</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мирзаев</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Mirzaev</surname><given-names>T. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мирзаев Турон Савронович – аспирант онкологического отделения хирургических методов лечения №7 (опухолей гепатопанкреатобилиарной зоны) </p><p>115478, г. Москва, Каширское шоссе, д. 23</p></bio><bio xml:lang="en"><p>Turon S. Mirzaev – Postgraduate Student of the Oncology Department of Surgical Treatment Methods No.7 (Tumors of the Hepatopancreatobiliary Zone)</p><p>23, Kashirskoye shosse, Moscow, 115478</p></bio><email xlink:type="simple">dyuran_1101@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7375-3378</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подлужный</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Podluzhny</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Подлужный Данил Викторович – кандидат медицинских наук, заведующий онкологическим отделением хирургических методов лечения №7 (опухолей гепатопанкреатобилиарной зоны) </p><p>115478, г. Москва, Каширское шоссе, д. 23</p></bio><bio xml:lang="en"><p>Danil V. Podluzhnyi – Cand. of Sci. (Med.), Head of the Oncology Department of Surgical Treatment Methods No.7 (Tumors of the Hepatopancreatobiliary Zone)</p><p>23, Kashirskoye shosse, Moscow, 115478</p></bio><email xlink:type="simple">dr.podluzhny@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7254-5411</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Израилов</surname><given-names>Р. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Izrailov</surname><given-names>R. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Израилов Роман Евгеньевич – доктор медицинских наук, заведующий отделением инновационной хирургии </p><p>111123, г. Москва, шоссе Энтузиастов, д. 86</p></bio><bio xml:lang="en"><p>Roman E. Izrailov – Doct. of Sci. (Med.), Head of the Department of Innovative Surgery </p><p>86, Shosse Entuziastov, 111123, Moscow</p><p> </p></bio><email xlink:type="simple">r.izrailov@mknc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9254-1346</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Патютко</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Patyutko</surname><given-names>Yu. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Патютко Юрий Иванович – доктор медицинских наук, профессор, главный научный сотрудник онкологического отделения хирургических методов лечения №7  (опухолей  гепатопанкреатобилиарной  зоны)</p><p>115478, г. Москва, Каширское шоссе, д. 23</p></bio><bio xml:lang="en"><p>Yuri I. Patyutko – Doct. of Sci. (Med.), Professor, Chief Researcher, Oncology Department of Surgical Treatment Methods No.7 (Tumors of the Hepatopancreatobiliary Zone)</p><p>23, Kashirskoye shosse, Moscow, 115478</p></bio><email xlink:type="simple">mikpat@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3899-8382</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глухов</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Glukhov</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Глухов Евгений Вячеславович – кандидат медицинских наук, научный сотрудник онкологического отделения хирургических методов лечения №7 (опухолей гепатопанкреатобилиарной зоны) </p><p>115478, г. Москва, Каширское шоссе, д. 23</p></bio><bio xml:lang="en"><p>Yevgeniy V. Glukhov – Cand. of Sci. (Med.), Researcher of the Oncology Department of Surgical Treatment Methods No.7 (Tumors of the Hepatopancreatobiliary Zone)</p><p>23, Kashirskoye shosse, Moscow, 115478</p></bio><email xlink:type="simple">drgluhov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2811-0549</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котельников</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotelnikov</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котельников Алексей Геннадьевич – доктор медицинских наук, профессор, ведущий научный сотрудник онкологического отделения хирургических методов лечения №7 (опухолей гепатопанкреатобилиарной зоны) </p><p>115478, г. Москва, Каширское шоссе, д. 23</p></bio><bio xml:lang="en"><p>Aleksey G. Kotelnikov – Doct. of Sci. (Med.), Professor, Leading Researcher of the Oncology Department of Surgical Treatment Methods No.7 (Tumors of the Hepatopancreatobiliary Zone)</p><p>23, Kashirskoye shosse, Moscow, 115478</p></bio><email xlink:type="simple">kotelnikovag@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ “Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Blokhin National Medical Research Center of Oncology of the Ministry of Health of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ “Московский клинический научный центр им. А.С. Логинова ДЗМ”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Loginov Moscow Clinical Scientific Center MHD</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>08</day><month>02</month><year>2021</year></pub-date><volume>26</volume><issue>1</issue><fpage>100</fpage><lpage>106</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мирзаев Т.С., Подлужный Д.В., Израилов Р.Е., Патютко Ю.И., Глухов Е.В., Котельников А.Г., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Мирзаев Т.С., Подлужный Д.В., Израилов Р.Е., Патютко Ю.И., Глухов Е.В., Котельников А.Г.</copyright-holder><copyright-holder xml:lang="en">Mirzaev T.S., Podluzhny D.V., Izrailov R.E., Patyutko Y.I., Glukhov E.V., Kotelnikov A.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hepato.elpub.ru/jour/article/view/646">https://hepato.elpub.ru/jour/article/view/646</self-uri><abstract><sec><title>Цель</title><p>Цель. Оценить возможность открытой дистальной субтотальной резекции поджелудочной железы с сохранением селезенки по поводу опухолей тела и хвоста поджелудочной железы.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проведен ретроспективный сравнительный анализ непосредственных результатов вмешательства с сохранением селезенки у 41 больного. Преимущественно выявляли доброкачественные опухоли или опухоли с низким потенциалом злокачественности тела и (или) хвоста органа. В 53 наблюдениях при опухолях поджелудочной железы различного гистогенеза с низким потенциалом злокачественности выполнили дистальную субтотальную резекцию поджелудочной железы со спленэктомией (контрольная группа).</p></sec><sec><title>Результаты</title><p>Результаты. Продолжительность операции с сохранением селезенки была на 12 мин меньше по сравнению с вмешательством, сопровождавшимся спленэктомией (p = 0,180). Отмечен достоверно меньший объем кровопотери во время операций с сохранением селезенки – на 460 мл (p = 0,0001). Число послеоперационных осложнений в группе с сохранением селезенки составило 15 (37%), после вмешательства со спленэктомией – 26 (49%; p = 0,227). Наружный панкреатический свищ после операций с сохранением селезенки отмечен у 13 (32%) больных, в другой группе – у 21 (40%; p = 0,429). Продолжительность пребывания больных в стационаре статистически незначимо различалась в сравниваемых группах: 18,6 ± 6,9 и 20,3 ± 5,4 дня (p = 0,123).</p></sec><sec><title>Заключение</title><p>Заключение. Открытая дистальная субтотальная резекция поджелудочной железы с сохранением селезенки является достаточно безопасным видом хирургического лечения больных доброкачественными опухолями и опухолями с низким потенциалом злокачественности тела и (или) хвоста органа. Операция является менее продолжительной, сопровождается меньшей частотой осложнений, достоверно меньшим объемом интраоперационной кровопотери по сравнению с аналогичной операцией, включающей спленэктомию.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To assess the possibility of open spleen-preserving distal subtotal pancreatic resection for tumors of the body and tail of the pancreas.</p></sec><sec><title>Material and methods</title><p>Material and methods. A retrospective comparative analysis of the immediate results of the spleen-preserving interventions in 41 patients was carried out. Mainly benign tumors or tumors with a low malignancy potential of the corpus and (or) the tail of the pancreas were detected. Distal subtotal pancreatectomy with splenectomy was performed in 53 patients with pancreatic tumors of different histogenesis with low malignancy potential (control group).</p></sec><sec><title>Results</title><p>Results. The duration of spleen-preserving distal subtotal pancreatectomy was 12 minutes shorter, compared with the distal subtotal pancreatectomy with splenectomy group (p = 0.180). Significantly lower volume of intraoperative blood loss during spleen-preserving procedure was noted – by 460 ml (p = 0.0001). The level of postoperative complications in the spleen-preserving pancreatectomy group was 15 (37%), while in the group of distal subtotal pancreatectomy with splenectomy was 26 (49%) (p = 0.227), respectively. External pancreatic fistula after spleenpreserving pancreatectomy was noted in 13 (32%) patients, in the other group in 21 (40%; p = 0.429). The duration of hospital stay did not statistically significantly differ in the compared groups and amounted to: 18.6 ± 6.9 and 20.3 ± 5.4 days (p = 0.123), respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. Open spleen-preserving pancreatectomy is a relatively safe type of surgical treatment for patients with benign tumors and tumors with a low potential for malignancy of the body and/or tail of the pancreas. The surgery is shorter in time, accompanied by a lower level of complications, significantly less intraoperative blood loss, compared with a similar procedure involving splenectomy.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>поджелудочная железа</kwd><kwd>опухоль</kwd><kwd>селезенка</kwd><kwd>дистальная резекция</kwd><kwd>спленэктомия</kwd><kwd>осложнения</kwd><kwd>результаты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pancreas</kwd><kwd>tumor</kwd><kwd>spleen</kwd><kwd>distal pancreatectomy</kwd><kwd>splenectomy</kwd><kwd>complications</kwd><kwd>results</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">ФГБУ НМИЦ им.Н.Н.Блохина</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Moekotte A.L., Lof S., White S.A., Marudanayagam R., Al S.B., Rahman S., Soonawalla Z., Deakin M., Aroori S., Ammori B., Gomez D., Marangoni G., Abu H.M. 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