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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">hepato</journal-id><journal-title-group><journal-title xml:lang="ru">Анналы хирургической гепатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5464</issn><issn pub-type="epub">2408-9524</issn><publisher><publisher-name>НЭИКОН ИСП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.16931/1995-5464.2016441-46</article-id><article-id custom-type="elpub" pub-id-type="custom">hepato-75</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПОДЖЕЛУДОЧНАЯ ЖЕЛЕЗА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PANCREAS</subject></subj-group></article-categories><title-group><article-title>Внутрибрюшная гипертензия и панкреатогенный перитонит</article-title><trans-title-group xml:lang="en"><trans-title>Intraabdominal Hypertension and Pancreatogenic Peritonitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зубрицкий</surname><given-names>В. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Zubritskiy</surname><given-names>V. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Doct. of Med. Sci., Professor, Chief Surgeon of Ministry of Internal Affairs of Russia, Head of the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Institute of Medical and Social Technologies at the Moscow State University of Food Production; Honorary Doctor of Chechen Republic, Honorary Doctor of the Russian Federation, Colonel of Internal Service</p></bio><bio xml:lang="en"><p>Doct. of Med. Sci., Professor, Chief Surgeon of Ministry of Internal Affairs of Russia, Head of the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Institute of Medical and Social Technologies at the Moscow State University of Food Production; Honorary Doctor of Chechen Republic, Honorary Doctor of the Russian Federation, Colonel of Internal Service</p></bio><email xlink:type="simple">zubvlad2009@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Забелин</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zabelin</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Doct. of Med. Sci., Professor of the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Institute of Medical and Social Technologies at the Moscow State University ofFood Production</p></bio><bio xml:lang="en"><p>Doct. of Med. Sci., Professor of the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Institute of Medical and Social Technologies at the Moscow State University ofFood Production</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колтович</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Koltovich</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Doct. of Med. Sci, Chief Surgeon at the Main Clinical Hospital of the Ministry of Internal Affairs of Russia, Professor of the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Institute of Medical and Social Technologies at Moscow State University of FoodProduction, Colonel of Internal Service</p></bio><bio xml:lang="en"><p>Doct. of Med. Sci, Chief Surgeon at the Main Clinical Hospital of the Ministryof Internal Affairs of Russia, Professor of the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Institute of Medical and Social Technologies at Moscow State University of FoodProduction, Colonel of Internal Service</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левчук</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Levchuk</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Doct. of Med. Sci., Professor of the Department of Surgery with the Course of Traumatology and Orthopedy at the Institute of Postgraduate Education, Pirogov National Medical Surgical Center</p></bio><bio xml:lang="en"><p>Doct. of Med. Sci., Professor of the Department of Surgery with the Course of Traumatology and Orthopedy at the Institute of Postgraduate Education, Pirogov National Medical Surgical Center</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айрапетян</surname><given-names>А. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Airapetyan</surname><given-names>A. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Cand. of Med. Sci., Professor at the Department of Surgery with the Courses ofAnesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Institute of Medical and Social Technologies at Moscow State University of Food Production.</p></bio><bio xml:lang="en"><p>Cand. of Med. Sci., Professor at the Department of Surgery with the Courses ofAnesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Institute of Medical and Social Technologies at Moscow State University of Food Production.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голубев</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Golubev</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Postgraduate Student of the Department of Surgical Infections, Pirogov National Medical Surgical Center</p></bio><bio xml:lang="en"><p>Postgraduate Student of the Department of Surgical Infections, Pirogov National Medical Surgical Center</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Розберг</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rozberg</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Doct. of Med. Sci., Professor at the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy.Moscow State University of Food Production</p></bio><bio xml:lang="en"><p>Doct. of Med. Sci., Professor at the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy.Moscow State University of Food Production</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коренев</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Korenev</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Teacher at the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Moscow State University of Food Production</p></bio><bio xml:lang="en"><p>Teacher at the Department of Surgery with the Courses of Anesthesiology and Reanimatology, Neurosurgery, Traumatology and Orthopedy. Moscow State University of Food Production</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт медико-социальных технологий Московского государственного университета пищевых производств</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Medical and Social Technologies at Moscow State University of Food Production</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный медико-хирургический центр им. Н.Н. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov National Medical and Surgical Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>24</day><month>12</month><year>2017</year></pub-date><volume>21</volume><issue>4</issue><fpage>41</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зубрицкий В.Ф., Забелин М.В., Колтович А.П., Левчук А.Л., Айрапетян А.Т., Голубев И.В., Розберг Е.П., Коренев Д.Н., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Зубрицкий В.Ф., Забелин М.В., Колтович А.П., Левчук А.Л., Айрапетян А.Т., Голубев И.В., Розберг Е.П., Коренев Д.Н.</copyright-holder><copyright-holder xml:lang="en">Zubritskiy V.F., Zabelin M.V., Koltovich A.P., Levchuk A.L., Airapetyan A.T., Golubev I.V., Rozberg E.P., Korenev D.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hepato.elpub.ru/jour/article/view/75">https://hepato.elpub.ru/jour/article/view/75</self-uri><abstract><p>Цель: определение прогностической ценности мониторинга внутрибрюшного давления при лечении больных панкреонекрозом в асептическую и инфекционную фазу.Материал и методы. Представлены результаты измерения и динамики внутрибрюшного давления у 78 больных панкреатогенным перитонитом.Результаты. Установлено, что панкреатогенный перитонит в 97,8% наблюдений осложняется повышением внутрибрюшного давления и развитием внутрибрюшной гипертензии. Выявлена корреляционная зависимость между величиной внутрибрюшного давления и распространенностью воспалительного процесса в брюш ной полости и забрюшинной клетчатке (p &lt; 0,05), а также между уровнем внутрибрюшного давления и степенью тяжести состояния по шкале APACHE II (p &lt; 0,05).Заключение. Продолжительное сохранение внутрибрюшной гипертензии у больных панкреатогенным перитонитом способствует прогрессированию полиорганной недостаточности и требует выполнения лапаротомии, одной из задач которой является уменьшение внутрибрюшного давления за счет санации брюшной полости и забрюшинной клетчатки.</p></abstract><trans-abstract xml:lang="en"><p>Aim. To define the prognostic value of intra-abdominal pressure monitoring in the treatment of patients with pancreatic necrosis in aseptic and infectious phases.Material and Methods. The article shows the results of measurements and dynamics of intra-abdominal pressure in 78 patients with pancreatogenic peritonitis.Results. It was established that pancreatogenic peritonitis was complicated by increased intra-abdominal pressure and the development of intra-abdominal hypertension in 97.8%. A correlation between IAP and severity of abdominal and retroperitoneal inflammation (p &lt; 0.05), as well as between IAP and APACHE II score was determined (p &lt; 0.05).Conclusion. Prolonged abdominal hypertension promotes the development of multiple organ failure and requires a laparotomy in order to reduce the intra-abdominal pressure via abdominal and retroperitoneal spaces sanitation</p></trans-abstract><kwd-group xml:lang="ru"><kwd>поджелудочная железа</kwd><kwd>острый панкреатит</kwd><kwd>панкреонекроз</kwd><kwd>внутрибрюшное давление</kwd><kwd>интра- абдоминальная гипертензия</kwd><kwd>панкреатогенный перитонит</kwd><kwd>полиорганная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pancreas</kwd><kwd>acute pancreatitis</kwd><kwd>pancreatic necrosis</kwd><kwd>intra-abdominal pressure</kwd><kwd>intra-abdominal hypertension</kwd><kwd>pancreatogenic peritonitis</kwd><kwd>multiple organ failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дюжева Т.Г., Шефер А.В. Внутрибрюшная гипертензия у больных тяжелым острым панкреатитом. Хирургия. Журнал им. Н.И. Пирогова. 2014; 1: 21–29.</mixed-citation><mixed-citation xml:lang="en">Dyuzheva T.G., Shefer A.V. Intra-abdominal hypertension in patients with severe acute pancreatitis. Khirurgiya. Zhurnal imeni N.I. Pirogova. 2014; 1: 21–29. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Зубрицкий В.Ф., Осипов И.С., Михопулос Т.А., Забелин М.В., Жиленков В.А. Синдром внутрибрюшной гиперензии у больных с деструктивными формами панкреатита. Хирургия. 2007; 1: 29–32.</mixed-citation><mixed-citation xml:lang="en">Zubritskiy V.F., Osipov I.S., Mikhopulos T.A., Zabelin M.V., Zhilenkov V.A. Abdominal hypertension syndrome in patients with destructive forms of pancreatitis. Khirurgiya. 2007; 1: 29–32. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Саввин Ю.Н., Зубрицкий В.Ф., Осипов И.С., Щёлоков А.Л., Забелин М.В., Крюков А.А. Является ли внутрибрюшная гипертензия причиной полиорганной недостаточности при деструктивном панкреатите? Военно-медицинский журнал. 2006; 11: 26–30.</mixed-citation><mixed-citation xml:lang="en">Savvin Yu.N., Zubritskiy V.F., Osipov I.S., Shchelokov A.L., Zabelin M.V., Kryukov A.A. Is abdominal hypertension cause of multiple organ failure in destructive pancreatitis? Voennomedicinskij zhurnal. 2006; 11: 26–30. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Гостищев В.К., Глушко В.А. Панкреонекроз и его осложнения, основные принципы хирургической тактики. Хирургия. 2003; 3: 50–54.</mixed-citation><mixed-citation xml:lang="en">De Waele J.J., Hesse U.J. Life saving abdominal decompression in a patient with severe acute pancreatitis. Acta Chir. Belg. 2005; 105 (1): 96–98.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Зубрицкий В.Ф., Левчук А.Л., Покровский К.А., Забелин М.В. Диагностика деструктивного панкреатита. М.: Миклош, 2010. 144 с.</mixed-citation><mixed-citation xml:lang="en">Cheatham M.L. Intra-abdominal hypertension and abdominal compartment syndrome. New Horiz. 1999; 7: 96–115.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Савельев B.C., Филимонов М.И., Куликов В.М., Сергеева Н.А., Орлов Б.Б., Кирсанов К.В., Койава С.С. Варианты течения панкреонекроза, определяющие выбор оптимальной тактики хирургического лечения. Анналы хирургии. 2006; 1: 40–44.</mixed-citation><mixed-citation xml:lang="en">Gecelter G., Fahoum B., Gardezi S., Schein M. Abdominal compartment syndrome in severe acute pancreatitis: An indication for a decompressing laparotomy? Dig. Surg. 2002; 19 (5): 4002–4005.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Филимонов М.И., Бурневич С.З. Хирургия панкрео некроза. 50 лекций по хирургии под редакцией В.С. Са вельева. М.: Медиа Медика, 2003. C. 241–248.</mixed-citation><mixed-citation xml:lang="en">Gostishchev V.K., Glushko V.A. Pancreatonecrosis and its complications, the basic principles of surgical tactics. Khirurgiya. 2003; 3: 50–54. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Zubrickiy V.F., Levchuk A.L., Pokrovskiy K.A., Zabelin M.V. Diagnostika destruktivnogo pankreatita [Diagnostics of destructive pancreatitis]. Moscow: Miklosh, 2010. 144 p. (In Russian)</mixed-citation><mixed-citation xml:lang="en">Zubrickiy V.F., Levchuk A.L., Pokrovskiy K.A., Zabelin M.V. Diagnostika destruktivnogo pankreatita [Diagnostics of destructive pancreatitis]. Moscow: Miklosh, 2010. 144 p. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Saveliev V.S., Filimonov M.I., Kulikov V.M., Sergeeva N.A., Orlov B.B., Kirsanov K.V., Koyava S.S. Possible courses of pancreatic necrosis, which determine the choice of optimal surgical treatment. Annaly khirurgii. 2006; 1: 40–44. (In Russian)</mixed-citation><mixed-citation xml:lang="en">Saveliev V.S., Filimonov M.I., Kulikov V.M., Sergeeva N.A., Orlov B.B., Kirsanov K.V., Koyava S.S. Possible courses of pancreatic necrosis, which determine the choice of optimal surgical treatment. Annaly khirurgii. 2006; 1: 40–44. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Filimonov M.I., Burnevich S.Z. Khirurgija pankreonekroza. 50 lekcij po khirurgii pod red. V.S. Savel'eva [Surgery of pancreatic necrosis. In Savel'ev V.S., ed. 50 lectures on surgery]. Moscow: Media Medika, 2003. P. 241–248. (In Russian)</mixed-citation><mixed-citation xml:lang="en">Filimonov M.I., Burnevich S.Z. Khirurgija pankreonekroza. 50 lekcij po khirurgii pod red. V.S. Savel'eva [Surgery of pancreatic necrosis. In Savel'ev V.S., ed. 50 lectures on surgery]. Moscow: Media Medika, 2003. P. 241–248. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Waele J., Hoste E., Blot S., Decruyenaer J., Colardyn F. Intraabdominal hypertension in patients with severe acute pancreatitis. Crit. Care. 2005; 9 (R452-R457): 37–44.</mixed-citation><mixed-citation xml:lang="en">Waele J., Hoste E., Blot S., Decruyenaer J., Colardyn F. Intraabdominal hypertension in patients with severe acute pancreatitis. Crit. Care. 2005; 9 (R452-R457): 37–44.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Balthazar E.J., Eobinson D.L., Magibow A.J., Ranson J.H. Acute pancreatitis: value of CT in establishing prognosis. Radiology. 1990; 174 (2): 331–336.</mixed-citation><mixed-citation xml:lang="en">Balthazar E.J., Eobinson D.L., Magibow A.J., Ranson J.H. Acute pancreatitis: value of CT in establishing prognosis. Radiology. 1990; 174 (2): 331–336.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Knaus W., Drager E., Dongles P. et al. APACHE-II: a severity of disease classification system. Critical Care. Med. 1985; 13 (10): 818–829.</mixed-citation><mixed-citation xml:lang="en">Knaus W., Drager E., Dongles P. et al. APACHE-II: a severity of disease classification system. Critical Care. Med. 1985; 13 (10): 818–829.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Ranson J.H.C., Kenneth M., Roses D.F., Fink S.D., Eng K., Spencer F.C. Prognosis sings and the role of operative management in acute pancreatitis. Surg. Gynecol. Obstet. 1974; 139 (1): 69–81.</mixed-citation><mixed-citation xml:lang="en">Ranson J.H.C., Kenneth M., Roses D.F., Fink S.D., Eng K., Spencer F.C. Prognosis sings and the role of operative management in acute pancreatitis. Surg. Gynecol. Obstet. 1974; 139 (1): 69–81.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Meldrum D.R., Moore F.A., Moore E.E., Franciose R.J., Sauaia A., Burch J.M. Prospective characterization and selective management of the abdominal compartment syndrome. Am. J. Surg. 1997; 174 (6): 667–672.</mixed-citation><mixed-citation xml:lang="en">Meldrum D.R., Moore F.A., Moore E.E., Franciose R.J., Sauaia A., Burch J.M. Prospective characterization and selective management of the abdominal compartment syndrome. Am. J. Surg. 1997; 174 (6): 667–672.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Malbrain M.L. Abdominal pressure in the critically ill. Curr.Opin. Crit. Care. 2000; 6 (1): 17–29.</mixed-citation><mixed-citation xml:lang="en">Malbrain M.L. Abdominal pressure in the critically ill. Curr.Opin. Crit. Care. 2000; 6 (1): 17–29.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Bradley E.L. A clinicallly based classification system for acute pancreatitis. Atlanta, Ga, (September 11–13). 1992; P. 586–590.</mixed-citation><mixed-citation xml:lang="en">Bradley E.L. A clinicallly based classification system for acute pancreatitis. Atlanta, Ga, (September 11–13). 1992; P. 586–590.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
