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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">hepato</journal-id><journal-title-group><journal-title xml:lang="ru">Анналы хирургической гепатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5464</issn><issn pub-type="epub">2408-9524</issn><publisher><publisher-name>НЭИКОН ИСП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.16931/1995-5464.2021-4-61-68</article-id><article-id custom-type="elpub" pub-id-type="custom">hepato-795</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭХИНОКОККОЗ ПЕЧЕНИ. ЭВОЛЮЦИЯ ДИАГНОСТИЧЕСКИХ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ</subject></subj-group></article-categories><title-group><article-title>Результаты мини-инвазивного лечения (PAIR) при эхинококкозе печени в сравнении с традиционными хирургическими методами</article-title><trans-title-group xml:lang="en"><trans-title>Results of minimally invasive treatment of liver echinococcosis in comparison with traditional surgical methods</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3355-8679</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нагасбеков</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nagasbekov</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нагасбеков Мадияр Сабырханович – докторант 1-го курса КазНМУ им. С. Д. Асфендиярова, Алматы; врач-хирург отделения общей хирургии Национального научного центра хирургии им. А. Н. Сызганова</p><p>050004, г. Алматы, ул. Желтоксан, д. 62</p><p>050012, г. Алматы, ул. Толе би, д. 94</p></bio><bio xml:lang="en"><p>Madiyar S. Nagasbekov – 1st year Doctoral Study Student at the Asfendiyarov Kazakh National Medical University; Surgeon of the Department of General Surgery of A. N. Syzganov National Scientific Center for Surgery</p><p>62, str. Zheltoksan, Almaty, 050004</p><p>94, str. Tole bi, Almaty, 050012</p></bio><email xlink:type="simple">nagasbekov@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2682-5591</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баймаханов</surname><given-names>Ж. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Baimakhanov</surname><given-names>Zh. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баймаханов Жасулан Болатбекович – канд. мед. наук, главный научный сотрудник, заведующий отделением общей хирургии</p><p>050004, г. Алматы, ул. Желтоксан, д. 62, тел.: +7-701-242-00-70</p></bio><bio xml:lang="en"><p>Zhassulan B. Baimakhanov – Cand. of Sci. (Med.), Chief Researcher, Head of the Department of General Surgery</p><p>62, str. Zheltoksan, Almaty, 050004, Phone: +7-701-242-00-70</p></bio><email xlink:type="simple">zh.baimakhan@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1288-0987</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каниев</surname><given-names>Ш. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaniyev</surname><given-names>Sh. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каниев Шокан Ахмедбекович – старший научный сотрудник, врач-хирург отделения ГПБХ и трансплантации печени</p><p>050004, г. Алматы, ул. Желтоксан, д. 62</p></bio><bio xml:lang="en"><p>Shokan A. Kaniyev – Senior Researcher, Surgeon of the Department of Hepatopancreatobiliary Surgery and Liver Transplantation</p><p>62, str. Zheltoksan, Almaty, 050004</p></bio><email xlink:type="simple">shokankaniyev@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8758-5061</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нурланбаев</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Nurlanbayev</surname><given-names>E. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нурланбаев Ерик Кумарбекович – канд. мед. наук, врач-хирург отделения общей хирургии</p><p>050004, г. Алматы, ул. Желтоксан, д. 62</p></bio><bio xml:lang="en"><p>Erik K. Nurlanbayev – Cand. of Sci. (Med.), Surgeon of the Department of General Surgery</p><p>62, str. Zheltoksan, Almaty, 050004</p></bio><email xlink:type="simple">enurlanbayev@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3513-1935</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чорманов</surname><given-names>А. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Chormanov</surname><given-names>A. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чорманов Алмат Турсынжанович – канд. мед. наук, заместитель председателя правления по научно-клинической и инновационной деятельности</p><p>050004, г. Алматы, ул. Желтоксан, д. 62</p></bio><bio xml:lang="en"><p>Almat Ch. Chormanov – Cand. of Sci. (Med.), Deputy Chairman of the Board on Scientific-Clinical and Innovation Activity</p><p>62, str. Zheltoksan, Almaty, 050004</p></bio><email xlink:type="simple">almat7676@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0049-5886</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баймаханов</surname><given-names>Б. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Baimakhanov</surname><given-names>B. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баймаханов Болатбек Бимендеевич – доктор мед. наук, профессор, академик НАН РК, председатель правления Национального научного центра хирургии им. А. Н. Сызганова</p><p>050004, г. Алматы, ул. Желтоксан, д. 62</p></bio><bio xml:lang="en"><p>Bolatbek B. Baimakhanov – Doct. of Sci. (Med.), Professor, Academician of the National Academy of Sciences of the Republic of Kazakhstan, Chairman of the Board of A. N. Syzganov National Scientific Center for Surgery</p><p>62, str. Zheltoksan, Almaty, 050004</p></bio><email xlink:type="simple">bolat.baimakhanov@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>АО “Национальный научный центр хирургии им. А. Н. Сызганова”; НАО “Казахский национальный медицинский университет им. С. Д. Асфендиярова”</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>“A. N. Syzganov National Scientific Center for Surgery” JSC; “Asfendiyarov Kazakh National Medical University”, NC JSC</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>АО “Национальный научный центр хирургии им. А. Н. Сызганова”</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>“A. N. Syzganov National Scientific Center for Surgery” JSC</institution><country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>29</day><month>10</month><year>2021</year></pub-date><volume>26</volume><issue>4</issue><fpage>61</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нагасбеков М.С., Баймаханов Ж.Б., Каниев Ш.А., Нурланбаев Е.К., Чорманов А.Т., Баймаханов Б.Б., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Нагасбеков М.С., Баймаханов Ж.Б., Каниев Ш.А., Нурланбаев Е.К., Чорманов А.Т., Баймаханов Б.Б.</copyright-holder><copyright-holder xml:lang="en">Nagasbekov M.S., Baimakhanov Z.B., Kaniyev S.A., Nurlanbayev E.K., Chormanov A.T., Baimakhanov B.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hepato.elpub.ru/jour/article/view/795">https://hepato.elpub.ru/jour/article/view/795</self-uri><abstract><sec><title>Цель</title><p>Цель. Анализ эффективности PAIR в сравнении с традиционными хирургическими методами.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Ретроспективно анализировали результаты лечения 199 больных эхинококкозом печени, перенесших оперативное лечение. Перицистэктомия выполнена 95 (47,7%) больным (1-я группа), традиционная эхинококкэктомия – 55 (27,6%; 2-я группа), PAIR – 49 (24,6%; 3-я группа). После операции все пациенты получали антипаразитарную терапию в течение 2 мес.</p></sec><sec><title>Результаты</title><p>Результаты. У больных 3-й группы было значительно больше кист стадии СЕ1 по сравнению со 2-й и 1-й группами – 38 (77,5%), 19 (34,5%) и 44 (46,3%; p &lt; 0,05). Во 2-й группе превалировали кисты СЕ2 и СЕ3. Продолжительность операции в 3-й группе была значительно меньше в сравнении с 1-й и 2-й группами – 58,2 (25–170), 194,8 (85–440) и 217 (75–540) мин (p &lt; 0,05). В 1-й группе интраоперационная кровопотеря была значительно больше, чем во 2-й, – 165,4 мл (10–1000) и 106,7 мл (10–500; p &lt; 0,05). В 3-й группе кровопотери не было. В послеоперационных осложнениях по Clavien–Dindo значимых различий между группами не было. Продолжительность пребывания больных 3-й группы в стационаре после операции была меньше по сравнению с 1-й и 2-й группами – 4,3 (2–11), 8,03 (5–16) и 8,08 (4–20) дня (p &lt; 0,05). Рецидив заболевания за период наблюдения не отмечен.</p></sec><sec><title>Заключение</title><p>Заключение. Оптимальный объем лечения основан на определении стадии заболевания. При СЕ1 наиболее эффективным методом является PAIR, характеризующаяся меньшей продолжительностью пребывания больных в стационаре после операции, ранним восстановлением трудоспособности. При мультивезикулярных кистах (СЕ2–СЕ3b) эффективны традиционные методы лечения.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To analyze the effectiveness of PAIR in comparison with traditional surgical methods.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A retrospective analysis of 199 patients who underwent surgical treatment of hepatic echinococcosis was carried out. Pericystectomy was performed on 95 (47.7%) patients (1st group), traditional echinococcectomy – 55 (27.6%; 2nd group), PAIR – 49 (24.6%; 3rd group). All patients received antihelmintic therapy for 2 months in the postoperative period.</p></sec><sec><title>Results</title><p>Results. Patients of the group 3 had significantly more CE1 cysts compared with the groups 2 and 1 – 38 (77.5%) versus 19 (34.5%) and 44 (46.3%; p &lt; 0.05) respectively. In group 2, CE2 and CE3 cysts were predominant. The duration of the operation in group 3 was significantly shorter than in group 1 and 2 – 58.2 (25–170), 194.8 (85–440) and 217 (75–540) minutes (p &lt; 0.05). In group 1, intraoperative blood loss was higher than in group 2 – 165.4 ml (10–1000) and 106.7 ml (10–500; p &lt; 0.05). There were no statistically significant differences between the groups in postoperative complications according to Clavien–Dindo. The duration of postoperational hospital stay of patients from the group 3 was shorter than for 1 and 2 groups – 4.3 (2–11) days, 8.03 (5–16) days and 8.08 (4–20) days (p &lt; 0.05) respectively. There was no disease recurrence during the follow-up period.</p></sec><sec><title>Conclusion</title><p>Conclusion. The optimal treatment should be based on the stage of the disease. In CE1, the most effective method is PAIR, which is characterized by a shorter postoperational hospital stay and early recovery. In multivesicular cysts (CE2-CE3b), traditional methods of treatment are effective.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>печень</kwd><kwd>эхинококкоз</kwd><kwd>эхинококкэктомия</kwd><kwd>перицистэктомия</kwd><kwd>PAIR</kwd><kwd>антипаразитарная терапия</kwd><kwd>альбендазол</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver</kwd><kwd>echinococcosis</kwd><kwd>echinococcectomy</kwd><kwd>pericystectomy</kwd><kwd>PAIR</kwd><kwd>antihelmintic therapy</kwd><kwd>albendazole</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Национальный научный центр хирургии им. А. Н. Сызганова, Алматы, Республика Казахстан; Казахский Национальный медицинский университет им. С. Д. Асфендиярова, Алматы, Казахстан</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шевченко Ю.Л., Назыров Ф.Г. Хирургия эхинококкоза. 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