hepatoАнналы хирургической гепатологииAnnaly khirurgicheskoy gepatologii = Annals of HPB Surgery1995-54642408-9524НЭИКОН ИСП10.16931/1995-5464.2022-3-68-73hepato-900Research ArticleПОДЖЕЛУДОЧНАЯ ЖЕЛЕЗАPANCREASПрогнозирование тяжелых послеоперационных осложнений в хирургии поджелудочной железы с помощью шкалы PREPARE: одноцентровое наблюдательное исследованиеPrediction of severe postoperative complications in pancreatic surgery using the Preoperative Pancreatic Resection (PREPARE) score: a single-center observational studyhttps://orcid.org/0000-0003-3407-4406БурловН. Н.BurlovN. N.

Бурлов Никита Николаевич – клинический ординатор онкологического отделения хирургических методов лечения (ООХМЛ) №6

191014, Санкт-Петербург, Литейный проспект, д. 37-39, Российская Федерация

Nikita N. Burlov – Clinical Resident, the Oncology Department of Surgical Methods of Treatment No. 6

37-39, Liteyny prospekt, Saint-Petersburg, 191014, Russian Federation

dikefsound@gmail.comhttps://orcid.org/0000-0002-0249-4759ХрыковГ. Н.KhrykovG. N.

Хрыков Глеб Николаевич – доктор мед. наук, заведующий онкологическим отделением хирургических методов лечения (ООХМЛ) №6

191014, Санкт-Петербург, Литейный проспект, д. 37-39, Российская Федерация

Gleb N. Khrykov – Doct. of Sci. (Med.), Head of the Oncology Department of Surgical Methods of Treatment No. 6

37-39, Liteyny prospekt, Saint-Petersburg, 191014, Russian Federation

ghrykov@mail.ruhttps://orcid.org/0000-0002-9229-3204БурловаЕ. А.BurlovaE. A.

Бурлова Елизавета Алексеевна – клинический ординатор отделения изотопной диагностики и позитронной эмиссионной томографии

197341, Санкт-Петербург, ул. Аккуратова, д. 2, Российская Федерация

Elizaveta A. Burlova – Clinical Resident, the Department of Isotope Diagnostics and Positron Emission Tomography

2, Akkuratova str., Saint-Petersburg, 197341, Russian Federation

983583@mail.ruhttps://orcid.org/0000-0003-2654-1190ШосткаК. Г.ShostkaK. G.

Шостка Кирилл Георгиевич – канд. мед. наук, заведующий онкологическим отделением хирургических методов лечения (ООХМЛ) №1

191014, Санкт-Петербург, Литейный проспект, д. 37-39, Российская Федерация

Kirill G. Shostka – Cand. of Sci. (Med.), Head of the Oncology Department of Surgical Methods of Treatment No. 1

37-39, Liteyny prospekt, Saint-Petersburg, 191014, Russian Federation

kirill_shostka@mail.ruЛенинградский областной клинический онкологический диспансер им. Л.Д. Романа (ЛОКОД)РоссияLeningrad Regional Clinical Oncological DispensaryRussian FederationФГБУ “Национальный медицинский исследовательский центр им. В.А. Алмазова”РоссияAlmazov National Medical Research CentreRussian Federation2022200920222736873Copyright © Бурлов Н.Н., Хрыков Г.Н., Бурлова Е.А., Шостка К.Г., 20222022Бурлов Н.Н., Хрыков Г.Н., Бурлова Е.А., Шостка К.Г.Burlov N.N., Khrykov G.N., Burlova E.A., Shostka K.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://hepato.elpub.ru/jour/article/view/900Цель

Цель. Оценка эффективности шкалы PREPARE в прогнозировании тяжелых осложнений после операций на поджелудочной железе.

Материал и методы

Материал и методы. В исследование “случай–контроль” включали оперированных на поджелудочной железе. Осложнения ≥II степени по Clavien–Dindo были обозначены как “тяжелые”. Пациентов разделили на 2 группы: “0–II степень” (контроль) и “III–V степень” (случай). Для всех больных были подсчитаны баллы и определены категории риска по шкале PREPARE.

Результаты

Результаты. Был включен 151 пациент: “0–II степень” – 102 (68%) наблюдения, “III–V степень” – 49 (32%). Использовали ROC-анализ: для баллов (AUC = 0,616; 95% ДИ 0,527–0,706; р = 0,014) и для категорий риска (AUC = 0,555; 95% ДИ 0,463–0,648; р = 0,241) шкалы PREPARE.

Заключение

Заключение. Полученные данные не позволяют в настоящее время рекомендовать шкалу PREPARE для прогнозирования осложнений операций на поджелудочной железе.

Aim

Aim. To evaluate the effectiveness of the PREPARE score in predicting severe complications after pancreatic surgery.

Materials and Methods

Materials and Methods. The case-control study included patients operated on the pancreas. Grade ≥III Clavien– Dindo complications were designated as “severe”. Patients were divided into two groups: “0–II degree” (control) and “III–V degree” (case). For all patients, scores were calculated, and risk categories were determined according to the PREPARE score.

Results

Results. The study included 151 patients: “0–II degree” – 102 (68%) observations, “III–V degree” – 49 (32%). ROC analysis was used for the scores (AUC = 0.616; 95% CI 0.527–0.706; p = 0.014) and for the risk categories (AUC = 0.555; 95% CI 0.463–0.648; p = 0.241) of the PREPARE score.

Conclusion

Conclusion. The obtained data do not currently enable us to recommend the PREPARE score for predicting complications of pancreatic surgery.

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The authors declare that there are no conflicts of interest present.