Preview

Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery

Advanced search

Hepatocellular carcinoma complicated by spontaneous rupture

https://doi.org/10.16931/10.16931/1995-5464.2023-2-104-109

Abstract

The paper presents a clinical case of hepatocellular carcinoma complicated by rupture. The underlying disease was asymptomatic prior to the development of complications. Despite blood loss of about 30-35% of circulating blood volume, hemorrhagic shock dominated the clinical picture of the acute condition. Neoplasm of the left hepatic lobe with necrosis and rupture was diagnosed by means of videolaparoscopy. Final hemostasis was impossible without liver resection. The tumor was excised within healthy tissues (R0). The authors performed a literature review and analysis. The value of the clinical case is determined by its rare complication.

About the Authors

S. V. Tarasenko
Ryazan State Medical University named after academician I.P. Pavlov; State Budgetary Institution of the Ryazan Region “City Clinical Emergency Hospital”
Russian Federation

Sergey V. Tarasenko – Doct. of Sci. (Med.), Professor, Head of Department of Hospital Surgery; Surgeon, Department of Emergency Diseases of the Liver and Pancreas

9, Vysokovoltnaya str., Ryazan, 390026

85, Stroykova str., Ryazan, 390026



U. V. Zhuchkova
Ryazan State Medical University named after academician I.P. Pavlov; State Budgetary Institution of the Ryazan Region “City Clinical Emergency Hospital”
Russian Federation

Uliana V. Zhuchkova – Cand. of Sci. (Med.), Associate Professor, Department of Hospital Surgery; Surgeon, Emergency Surgery Unit

9, Vysokovoltnaya str., Ryazan, 390026, Russian Federation

85, Stroykova str., Ryazan, 390026



M. V. Kalinin
State Budgetary Institution of the Ryazan Region “City Clinical Emergency Hospital”
Russian Federation

Michael V. Kalinin – Surgeon, Department of Emergency Diseases of the Liver and Pancreas

85, Stroykova str., Ryazan, 390026



References

1. Chen M.F., Hwang T.L., Jeng L.B., Jan Y.Y., Wang C.S. Clinical experience with hepatic resection for ruptured hepatocellular carcinoma. Hepatogastroenterology. 1995; 42 (2): 166–168.

2. Recordare A., Bonariol L., Caratozzolo E., Callegari F., Bruno G., Di Paola F., Bassi N. Management of spontaneous bleeding due to hepatocellular carcinoma. Minerva Chir. 2002; 57 (3): 347–356.

3. Battula N., Madanur M., Priest O., Srinivasan P., O'Grady J., Heneghan M.A., Bowles M., Muiesan P., Heaton N., Rela M. Spontaneous rupture of hepatocellular carcinoma: a Western experience. Am. J. Surg. 2009; 197 (2): 164–167. https://doi.org/10.1016/j.amjsurg.2007.10.016

4. Lai E.C., Lau W.Y. Spontaneous rupture of hepatocellular carcinoma: a systematic review. Arch. Surg. 2006; 141 (2): 191– 198. https://doi.org/10.1001/archsurg.141.2.191

5. Wu J.J., Zhu P., Zhang Z.G., Zhang B.X., Shu C., Mba’nboKoumpa A.A., Zhang Z.W., Huang Z.Y., Zhang W.G., Lau W.Y., Chen X.P. Spontaneous rupture of hepatocellular carcinoma: optimal timing of partial hepatectomy. Eur. J. Surg. Oncol. 2019; 45 (10): 1887–1894. https://doi.org/10.1016/j.ejso.2019.02.033

6. Gao W., Li T., Zhao W., Wang D. Risk factors of spontaneous rupture and hemorrhage of primary hepatocellular carcinoma and prognosis analysis of different treatment methods. J. Prog. Modern Gen. Surg. China. 2016; 19: 527–530.

7. Yin D., Qu Z., Liu L., Jiang H. Treatment status of ruptured primary liver cancer hemorrhage. J. World Chin. J. Gastroenterol. 2007; 06: 601–605.

8. Liu C.L., Fan S.T., Lo C.M., Tso W.K., Poon R.T., Lam C.M., Wong J. Management of spontaneous rupture of hepatocellular carcinoma: single-center experience. J. Clin. Oncol. 2001; 19 (17): 3725–3732. https://doi.org/10.1200/JCO.2001.19.17.3725

9. Xia F., Ndhlovu E., Zhang M., Chen X., Zhang B., Zhu P. Ruptured hepatocellular carcinoma: current status of research. Front. Oncol. 2022; 17 (12): 848–903. https://doi.org/10.3389/fonc.2022.848903

10. Li Z., Tian J., Feng H., Liu Y., Gao Y., Li M. Clinical application study of contrast-enhanced ultrasound in rapid diagnosis of liver cancer hemorrhage. J. Chin. J. Med. Ultrasound. 2014; 11: 114–119.

11. Liu W. Discussion on the clinical value of contrast-enhanced ultrasound in rapid diagnosis of liver cancer hemorrhage. J. Modern Diagnosis Treat. 2014; 25: 4834–4835.

12. Durot I., Wilson S.R., Willmann J.K. Contrast-enhanced ultrasound of malignant liver lesions. Abdom. Radiol. (NY). 2018; 43 (4): 819–847. https://doi.org/10.1007/s00261-017-1360-8

13. Pombo F., Arrojo L., Perez-Fontan J. Haemoperitoneum secondary to spontaneous rupture of hepatocellular carcinoma: CT diagnosis. Clin. Radiol. 1991; 43 (5): 321–322. https://doi.org/10.1016/s0009-9260(05)80539-2

14. Abraham R., Vyas D., Narayan M., Vyas A. Strategically leapfrogging education in prehospital trauma management: four-tiered training protocols. Am. J. Robot. Surg. 2015; 2 (1): 9–15. https://doi.org/10.1166/ajrs.2015.1022

15. Zhou J., Sun H., Wang Z., Cong W., Wang J., Zeng M., Zhou W., Bie P., Liu L., Wen T., Han G., Wang M., Liu R., Lu L., Ren Z., Chen M., Zeng Z., Liang P., Liang C., Chen M., Yan F., Wang W., Ji Y., Yun J., Cai D., Chen Y., Cheng W., Cheng S., Dai C., Guo W., Hua B., Huang X., Jia W., Li Y., Li Y., Liang J., Liu T., Lv G., Mao Y., Peng T., Ren W., Shi H., Shi G., Tao K., Wang W., Wang X., Wang Z., Xiang B., Xing B., Xu J., Yang J., Yang J., Yang Y., Yang Y., Ye S., Yin Z., Zhang B., Zhang B., Zhang L., Zhang S., Zhang T., Zhao Y., Zheng H., Zhu J., Zhu K., Liu R., Shi Y., Xiao Y., Dai Z., Teng G., Cai J., Wang W., Cai X., Li Q., Shen F., Qin S., Dong J., Fan J. Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2019 edition). Liver Cancer. 2020; 9 (6): 682–720. https://doi.org/10.1159/000509424

16. Lai E.C., Wu K.M., Choi T.K., Fan S.T., Wong J. Spontaneous ruptured hepatocellular carcinoma. An appraisal of surgical treatment. Ann. Surg. 1989; 210 (1): 24–28. https://doi.org/10.1097/00000658-198907000-00004

17. Akhmedov S.M., Safarov B.J., Saidmurodov A.S., Tabarov Z.V. Extensive liver resections for locally advanced cancer. Avicenna Bulletin. 2014; 1: 30–35. (In Russian)

18. Chiappa A., Zbar A., Audisio R.A., Paties C., Bertani E., Staudacher C. Emergency liver resection for ruptured hepatocellular carcinoma complicating cirrhosis. Hepatogastroenterology. 1999; 46 (26): 1145–1150.

19. Vergara V., Muratore A., Bouzari H., Polastri R., Ferrero A., Galatola G., Capussotti L. Spontaneous rupture of hepatocelluar carcinoma: surgical resection and long-term survival. Eur. J. Surg. Oncol. 2000; 26 (8): 770–772. https://doi.org/10.1053/ejso.2000.1001

20. Lee C.Y., Chau G.Y., Wei C.Y., Chao Y., Huang Y.H., Huo T.I., Hou M.C., Su Y.H., Wu J.C., Su C.W. Surgical resection could provide better outcomes for patients with hepatocellular carcinoma and tumor rupture. Sci. Rep. 2022; 12 (1): 8343. https://doi.org/10.1038/s41598-022-12350-x


Review

For citations:


Tarasenko S.V., Zhuchkova U.V., Kalinin M.V. Hepatocellular carcinoma complicated by spontaneous rupture. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2023;28(2):104-109. (In Russ.) https://doi.org/10.16931/10.16931/1995-5464.2023-2-104-109

Views: 350


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1995-5464 (Print)
ISSN 2408-9524 (Online)