Results of transjugular intrahepatic portosystemic shunt combined with selective gastric vein embolization
https://doi.org/10.16931/1995-5464.2023-3-31-38
Abstract
Aim. To improve the outcomes of surgical treatment of patients with cirrhosis complicated by clinically significant portal hypertension by performing TIPS with selective embolization of gastric veins.
Materials and methods. The authors explored the immediate and long-term outcomes of treatment of 62 patients with liver cirrhosis: group I included 27 patients who underwent TIPS with selective embolization of one left gastric vein; group II included 35 patients who underwent TIPS with selective embolization of ≥2 gastric veins. The authors tested a non-invasive method for predicting the risk of bleeding from gastric and oesophageal varices after TIPS with selective embolization of gastric veins and compared MRI and EGD results before and after the surgery (n = 14).
Results. The maximum follow-up duration comprised 72 months. Bleeding from the oesophageal veins was not reported in the early period after TIPS with embolization of the left gastric vein, however, the long-term bleeding developed in 2 patients (7.4%). In 6–72 months following TIPS with embolization of the left gastric vein and posterior gastric vein, as well as short gastric veins (when indicated), no recurrences of variceal bleeding appeared. The method of predicting the risk of bleeding after TIPS proved to be effective in all 14 patients in the follow-up period of 6 months (invention application No. 2022129022).
Conclusion. The obtained results confirmed the efficacy of TIPS combined with gastric vein embolization. The unique patent solution determined the technique, indications and peculiarities of the intervention.
About the Authors
N. G. SapronovaRussian Federation
Natalia G. Sapronova – Doct. оf Sci. (Med.), Associate Professor, Head of the Department of Surgical Diseases No. 1 , Rostov State Medical University.
d.241/122, apt. 39, str. Filimonovskaya, Rostov-on-Don, 344022
D. S. Kalinin
Russian Federation
Denis S. Kalinin – Cardiovascular Surgeon, Vascular Surgery Unit, Postgraduate Student, Department of Surgical Diseases No. 1, Rostov State Medical University.
d.241/122, apt. 39, str. Filimonovskaya, Rostov-on-Don, 344022
Phone: +7-928-193-79-70
E. V. Kosovtsev
Russian Federation
Evgeniy V. Kosovtsev – Cand. оf Sci. (Med.), Associate Professor, Surgery Department No. 4, Head of Radiosurgical Methods of Diagnosis and Treatment, Rostov State Medical University.
d.241/122, apt. 39, str. Filimonovskaya, Rostov-on-Don, 344022
Yu. V. Khoronko
Russian Federation
Yuri V. Khoronko – Doct. оf Sci. (Med.), Professor, Head of the Department of Operative Surgery and Topographic Anatomy, Rostov State Medical University.
d.241/122, apt. 39, str. Filimonovskaya, Rostov-on-Don, 344022
D. V. Stagniev
Russian Federation
Dmitry V. Stagniev – Cand. оf Sci. (Med.), Associate Professor, Department of Surgical Diseases No. 1, Rostov State Medical University.
d.241/122, apt. 39, str. Filimonovskaya, Rostov-on-Don, 344022
E. Yu. Khoronko
Russian Federation
Evgeniy Yu. Khoronko – Cand. оf Sci. (Med.), Associate Professor of the Department of Surgical Diseases No. 1, Rostov State Medical University.
d.241/122, apt. 39, str. Filimonovskaya, Rostov-on-Don, 344022
R. E. Kosovtsev
Russian Federation
Roman Е. Kosovtsev – 6th year Student, Rostov State Medical University.
d.241/122, apt. 39, str. Filimonovskaya, Rostov-on-Don, 344022
References
1. Khoronko Yu.V., Sapronova N.G., Kosovtsev E.V., Khoronko E.Yu., Kantsurov R.N., Ashimov I.A. Selection of a portosystemic shunt placement procedure (TIPS) in the treatment of complicated portal hypertension. Annaly khirurgicheskoy gepatologii = Annals of HPB surgery. 2022; 27 (2): 20–30. https://doi.org/10.16931/1995-5464.2022-2-20-30 (In Russian)
2. Onnitsev I.E., Dzidzava I.I., Kotiv B.N., Ivanusa S.Y., Zubarev P.N., Alentiev S.A., Parfenov A.O. Prevention of early postoperative thrombosis of portocaval shunts in patients with hepatic cirrhosis. Kursk Scientific and Practical Bulletin "Man and His Health". 2018; 1: 54–60. https://doi.org/10.21626/vestnik/2018-1/09 (In Russian)
3. De Franchis R., Bosch J., Garcia-Tsao G., Reiberger Т., Ripoll С. Baveno VII – Renewing consensus in portal hypertension. J. Hepatol. 2022; 76 (4): 959–974. https://doi:org/10.1016/j.jhep.2021.12.022
4. Huang Y., Li J., Zheng T., Ji D., Wong Y.J., You H., Gu Y., Li M., Zhao L., Li S., Geng S., Yang N., Chen G., Wang Y., Kumar M., Jindal A., Qin W., Chen Z., Xin Y., Jiang Z., Chi X., Cheng J., Zhang M., Liu H., Lu M., Li L., Zhang Y., Pu L., Ma D., He Q., Tang S., Wang C., Liu S., Wang J., Liu Y., Liu C., Liu H., Sarin S.K., Xiaolong Q.I. Development and validation of a machine learning-based model for varices screening in compensated cirrhosis (CHESS2001): an international multicenter study. Gastrointest. Endosc. 2023; 97 (3): 435–444. https://doi.org/10.1016/j.gie.2022.10.018
5. Lebezev V.M., Manukyan G.V., Fandeev E.E., Kitsenko E.A., Musin R.A., Kazakevich E.A., Rizaeva S.A., Bobyleva Ya.S. “Left gastric vein to inferior vena cava” bypass in patients with portal hypertension. Annaly khirurgicheskoy gepatologii = Annals of HPB surgery. 2020; 25 (1): 27–37. https://doi.org/10.16931/1995-5464.2020127-37
Review
For citations:
Sapronova N.G., Kalinin D.S., Kosovtsev E.V., Khoronko Yu.V., Stagniev D.V., Khoronko E.Yu., Kosovtsev R.E. Results of transjugular intrahepatic portosystemic shunt combined with selective gastric vein embolization. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2023;28(3):31-38. (In Russ.) https://doi.org/10.16931/1995-5464.2023-3-31-38