Pancreaticoduodenectomy in multivisceral surgeries: clinical experience of two institutions

Aim. To describe the experience of multivisceral surgeries involving pancreaticoduodenectomy for tumors of various localizations, performed in two Russian medical institutions.

Materials and methods. A retrospective study was conducted on the outcomes of 251 multivisceral surgeries with pancreaticoduodenectomy performed in two medical institutions from January 2011 to April 2024.

Results. Tumors of pancreatic head, duodenum and large papilla of duodenum were detected in 180 cases (71.7%); colorectal tumors in 36 cases (14.3%); gastric tumors in 24 cases (9.6%); extrahepatic bile duct and gallbladder tumors in 7 cases (2.8%); renal tumors in 3 cases (1.2%); retroperitoneal tumor in 1 case (0.4%). In 107 cases, the surgery was combined with liver resection, including hemihepatectomy in 7 cases. Pancreaticoduodenectomy was combined with colorectal resection in 95 cases. Despite the extreme variability in the extent of multivisceral surgeries with pancreaticoduodenectomy, the complication rate and mortality amounted to 65.7% and 7.2%, respectively.

Conclusion. The structure of multivisceral surgeries with pancreaticoduodenectomy appears to be extremely heterogeneous in terms of localization, tumor histogenesis, and the volume of surgical interventions. The frequency of postoperative complications and mortality indicates acceptable tolerability of such surgeries.

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