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The role of endoscopic classification-based typing of major duodenal papilla adenomas in the selection of surgical resection procedures

https://doi.org/10.16931/1995-5464.2025-3-90-98

Abstract

Aim. To evaluate the impact of endoscopic procedure selection in the treatment of patients with major duodenal papilla adenomas, using a newly developed endoscopic classification of these lesions.

Materials and Methods. From 2000 to 2024, endoscopic surgical resection of major duodenal papilla adenomas was performed in 200 patients. Preoperative diagnosis was based on endoscopic ultrasound (EUS) in 165 cases, while in 35 cases, EUS was not used.

Results. Technical success of endoscopic resection of major duodenal papilla adenomas was 100% in both groups. The incidence of postoperative complications was 16.9% in the main group and 40% in the comparison group. During long-term follow-up, the adenoma recurrence rate was 6.6% in the main group and 20% in the comparison group.

Conclusion. A patient-specific choice of the optimal procedure for surgical resection of major duodenal papilla adenomas, depending on classification-based typing of the neoplasm, reduces the rate of postoperative complications and resection radicality.

About the Authors

Yu. G. Starkov
A.V. Vishnevsky National Medical Research Center of Surgery of the Ministry of Health of the Russian Federation
Russian Federation

Yury G. Starkov – Doct. of Sci. (Med.), Professor, Head of the Department of Endoscopic Surgery

27, Bol'shaya Serpukhovskaya str., Moscow, 117997



A. I. Vagapov
A.V. Vishnevsky National Medical Research Center of Surgery of the Ministry of Health of the Russian Federation
Russian Federation

Ayubkhan I. Vagapov – Resident of the Department of Endoscopic Surgery

27, Bol'shaya Serpukhovskaya str., Moscow, 117997



R. D. Zamolodchikov
A.V. Vishnevsky National Medical Research Center of Surgery of the Ministry of Health of the Russian Federation
Russian Federation

Rodion D. Zamolodchikov – Cand. of Sci. (Med.), Research Fellow of the Department of Endoscopic Surgery

27, Bol'shaya Serpukhovskaya str., Moscow, 117997Dzhantukhanova S.V.



S. V. Dzhantukhanova
A.V. Vishnevsky National Medical Research Center of Surgery of the Ministry of Health of the Russian Federation
Russian Federation

Seda V. Dzhantukhanova – Cand. of Sci. (Med.), Senior Research Fellow of the Department of Endoscopic Surgery

27, Bol'shaya Serpukhovskaya str., Moscow, 117997



References

1. Panzeri F., Crippa S., Castelli P., Aleotti F., Pucci A., Partelli S., Zamboni G., Falconi M. Management of ampullary neoplasms: a tailored approach between endoscopy and surgery. World J. Gastroenterol. 2015; 21 (26): 7970–7987. https://doi.org/10.3748/wjg.v21.i26.7970

2. Bohnacker S., Seitz U., Nguyen D., Thonke F., Seewald S., deWeerth A., Ponnudurai R., Omar S., Soehendra N. Endoscopic resection of benign tumors of the duodenal papilla without and with intraductal growth. Gastrointest. Endosc. 2005; 62 (4): 551–560. https://doi.org/10.1016/j.gie.2005.04.053

3. Ardengh J.C., Kemp R., Lima-Filho É.R., Dos Santos J.S. Endoscopic papillectomy: the limits of the indication, technique and results. World J. Gastrointest. Endosc. 2015; 7 (10): 987–994. https://doi.org/10.4253/wjge.v7.i10.987

4. Starkov Yu.G., Dzhantukhanova S.V., Zamolodchikov R.D., Vagapov A.I. Endoscopic classification of neoplasms of the major duodenal papilla. Oncology Bulletin of the Volga Region. 2022; 13 (4): 25–30. https://doi.org/10.32000/2078-1466-2022-4-25-30 (In Russian)

5. Hyun J.J., Lee T.H., Park J.S., Han J.H., Jeong S., Park S.M., Lee H.S., Moon J.H., Park S.H. A prospective multicenter study of submucosal injection to improve endoscopic snare papillectomy for ampullary adenoma. Gastrointest. Endosc. 2017; 85 (4): 746–755. https://doi.org/10.1016/j.gie.2016.08.013

6. De Palma G.D., Luglio G., Maione F., Esposito D., Siciliano S., Gennarelli N., Cassese G., Persico M., Forestieri P. Endoscopic snare papillectomy: a single institutional experience of a standardized technique. A retrospective cohort study. Int. J. Surg. 2015; 13 (1): 180–183. https://doi.org/10.1016/j.ijsu.2014.11.045

7. Starkov Yu.G., Vagapov A.I., Zamolodchikov R.D., Dzhantukhanova S.V. Endoscopic classification of major duodenal papilla adenomas. Annaly khirurgicheskoy gepatologii = Annals of HPB surgery. 2024; 29 (1): 12–20. https://doi.org/10.16931/1995-5464.2024-1-12-20 (In Russian)

8. Binmoeller K.F., Boaventura S., Ramsperger K., Soehendra N. Endoscopic snare excision of benign adenomas of the papilla of Vater. Gastrointest. Endosc. 1993; 39 (2): 127–131. https://doi.org/10.1016/s0016-5107(93)70051-6

9. Starkov Yu.G., Vagapov A.I., Zamolodchikov R.D., Dzhantukhanova S.V., Ibragimov A.S. Intraluminal endoscopic complex approach in the treatment of a patient with adenoma of the major duodenal papilla, choledocholithiasis and stricture of the terminal common bile duct. Experimental and Clinical Gastroenterology. 2023; 211 (3): 161–167. https://doi.org/10.31146/1682-8658-ecg-211-3-161-167 (In Russian)

10. Starkov Yu.G., Vagapov A.I., Zamolodchikov R.D., Dzhantukhanova S.V. Intraductal radiofrequency ablation for neoplasms of the major duodenal papilla with intraductal spread. Pirogov Russian Journal of Surgery = Khirurgiya. Zhurnal imeni N.I. Pirogova. 2024; 6: 514. https://doi.org/10.17116/hirurgia20240615 (In Russian)

11. Kang S.H., Kim K.H., Kim T.N., Jung M.K., Cho C.M., Cho K.B., Han J.M., Kim H.G., Kim H.S. Therapeutic outcomes of endoscopic papillectomy for ampullary neoplasms: retrospective analysis of a multicenter study. BMC Gastroenterol. 2017; 17 (1): 69. https://doi.org/10.1186/s12876-017-0626-5

12. Irani S., Arai A., Ayub K., Biehl T., Brandabur J.J., Dorer R., Gluck M., Jiranek G., Patterson D., Schembre D., Traverso L.W., Kozarek R.A. Papillectomy for ampullary neoplasm: results of a single referral center over a 10-year period. Gastrointest. Endosc. 2009; 70 (5): 923–932. https://doi.org/10.1016/j.gie.2009.04.015

13. Boix J., Lorenzo-Zúñiga V., Moreno de Vega V., Domènech E., Gassull M.A. Endoscopic resection of ampullary tumors: 12-year review of 21 cases. Surg. Endosc. 2009; 23 (1): 45–49. https://doi.org/10.1007/s00464-008-9866-3

14. Ceppa E.P., Burbridge R.A., Rialon K.L., Omotosho P.A., Emick D., Jowell P.S., Branch M.S., Pappas T.N. Endoscopic versus surgical ampullectomy: an algorithm to treat disease of the ampulla of Vater. Ann. Surg. 2013; 257 (2): 315–322. https://doi.org/10.1097/SLA.0b013e318269d010

15. Starkov Yu.G., Zamolodchikov R.D., Olovyanny V.E., Kuznetsov A.V., Ovechkin A.I. Endoskopiya v Rossijskoj Federacii [Endoscopy in the Russian Federation]. Moscow: RUSTPRESS, 2024. P. 76–96.


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Starkov Yu.G., Vagapov A.I., Zamolodchikov R.D., Dzhantukhanova S.V. The role of endoscopic classification-based typing of major duodenal papilla adenomas in the selection of surgical resection procedures. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2025;30(3):90-98. (In Russ.) https://doi.org/10.16931/1995-5464.2025-3-90-98

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ISSN 1995-5464 (Print)
ISSN 2408-9524 (Online)