Choledochoduodenal fistula in a pediatric patient with gallstone disease
https://doi.org/10.16931/1995-5464.2025-4-84-88
Abstract
We report a clinical case of a rare complication of gallstone disease in a pediatric patient – a choledochoduodenal fistula. A 9-year-old female had been treated conservatively for cholangitis. After transfer to our center, duodenoscopy revealed a choledochoduodenal fistula. Initially performed endoscopic sphincterotomy up to the level of the fistula and balloon lithoextraction resulted in resolution of biliary obstruction and cholangitis. Cholecystectomy did not follow because of marked inflammatory infiltration and a high risk of perioperative complications. However, the patient subsequently developed recurrent biliary colic successfully managed by emergency laparoscopic cholecystectomy. The study addresses diagnostic challenges and aspects of modern endoscopy, and provides a review of the relevant literature.
About the Authors
A. M. EfremenkovRussian Federation
Artem M. Efremenkov – Cand. of Sci. (Med.), Head of the Pediatric Surgical Department, Central Clinical Hospital of the Presidential Administration of the Russian Federation; Associate Professor of the Department of Pediatric Surgery named after academician S.Ya. Doletsky, Russian Medical Academy of Continuous Professional Education
15, Marshala Timoshenko str., Moscow, 121359
2/1 bld. 1, Barrikadnaya str., Moscow, 125993
E. N. Solodinina
Russian Federation
Elena N. Solodinina – Doct. of Sci. (Med.), Head of the Endoscopy Department, Central Clinical Hospital of the Presidential Administration of the Russian Federation; Associate Professor of the Department of Surgery with courses in Endoscopy and Pediatric Surgery, Central State Medical Academy of the Presidential Administration of the Russian Federation
15, Marshala Timoshenko str., Moscow, 121359
19 bld. 1A, Marshala Timoshenko str., Moscow, 121359
A. P. Zykin
Russian Federation
Alexandr P. Zykin – Cand. of Sci. (Med.), Pediatric Surgeon, Endoscopist at the Pediatric Surgical Department, Central Clinical Hospital of the Presidential Administration of the Russian Federation; Assistant Professor of the Department of Pediatric Surgery named after academician S.Ya. Doletsky, Russian Medical Academy of Continuous Professional Education
15, Marshala Timoshenko str., Moscow, 121359
2/1 bld. 1, Barrikadnaya str., Moscow, 125993
N. V. Fomicheva
Russian Federation
Natalia V. Fomicheva – Cand. of Sci. (Med.), Endoscopist of the Endoscopy Department
15, Marshala Timoshenko str., Moscow, 121359
References
1. Uhe I., Litchinko A., Liot E. Peptic ulcer disease complicated with choledocho-duodenal fistula and gastro-intestinal bleeding: a case report and review of the literature. Front. Surg. 2023; 10: 1206828. https://doi.org/10.3389/fsurg.2023.1206828
2. Kachi A., Kanj M., Khaled C., Nassar C., Bou Rached C., Kansoun A. Choledochoduodenal fistula secondary to peptic ulcer disease: a case report. Am. J. Case Rep. 2019; 20: 398–401. https://doi.org/10.12659/AJCR.915600
3. Chaudhari D., Saleem A., Murthy R., Baron T., Young M. Choledochoduodenal fistula after biliary placement of a selfexpanding metallic stent for palliation of pancreatic cancer. Endoscopy. 2013; 45 Suppl 2 UCTN: E77. https://doi.org/10.1055/s-0032-1326266
4. Duman L., Savas C., Aktas A.R., Akcam M. Choledochoduodenal fistula: an unusual cause of recurrent cholangitis in children. J. Indian Assoc. Pediatr. Surg. 2014; 19 (3): 172–174. https://doi.org/10.4103/0971-9261.136479
5. Chao H.C., Chen S.Y., Luo C.C., Wang C.J. Choledochoduodenal fistula caused by blunt abdominal trauma in a child. J. Pediatr. Surg. 2008; 43 (12): e31–e33. https://doi.org/10.1016/j.jpedsurg.2008.09.004
6. Wu M.B., Zhang W.F., Zhang Y.L., Mu D., Gong J.P. Choledochoduodenal fistula in Mainland China: a review of epidemiology, etiology, diagnosis and management. Ann. Surg. Treat. Res. 2015; 89 (5): 240–246. https://doi.org/10.4174/astr.2015.89.5.240
7. Vorobey A.V., Orlovsky Yu.N., Vizhinis E.I., Shuleyko A.Ch. Surgical treatment of biliobiliary and biliodigestive fistulas. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2016; 21 (3): 92–100. https://doi.org/10.16931/1995-5464.2016392-100 (In Russian)
8. Misra D., Mirza U., Vakiti A., Padala S.A. A Rare presentation of choledochoduodenal fistula due to ovarian cancer metastasis. J. Investig. Med. High Impact. Case Rep. 2020; 8: 2324709620934680. https://doi.org/10.1177/2324709620934680
9. Knipping S., Rajpoot R., Houshyar R. Choledochoduodenal fistula in the setting of Crohn's disease. Radiol. Case Rep. 2016; 11 (4): 309–312. https://doi.org/10.1016/j.radcr.2016.08.018
10. Skipenko O.G., Polishchuk L.O., Chekunov D.A., Khrustaleva M.V., Kim S.Yu. The burst of the hydatid cyst into the biliary tree, complicated by the choledochduodenal fistula. Pirogov Russian Journal of Surgery. 2012; (7): 80–82. (In Russian)
11. Song T.J., Hyun Y.S., Lee S.S., Park do H., Seo D.W., Lee S.K., Kim M.H. Endoscopic ultrasoundguided choledochoduodenostomies with fully covered self-expandable metallic stents. World J. Gastroenterol. 2012; 18 (32): 4435–4440. https://doi.org/10.3748/wjg.v18.i32.4435
12. Zong K.C., You H.B., Gong J.P., Tu B. Diagnosis and management of choledochoduodenal fistula. Am. Surg. 2011; 77 (3): 348–350.
13. Ikeda S., Okada Y. Classification of choledochoduodenal fistula diagnosed by duodenal fiberscopy and its etiological significance. Gastroenterology. 1975; 69 (1): 130–137.
14. Gong J.P., Zhou Y.B., Han B.L. Diagnosis and classification of choledochoduodenal fistula. Chin. J. Digest. Endosc. 1999; 2: 42–43.
15. Jaballah S., Sabri Y., Karim S. Choledochoduodenal fistula due to duodenal peptic ulcer. Dig. Dis. Sci. 2001; 46 (11): 2475–2479. https://doi.org/10.1023/a:1012384105644
16. Agarwal N., Sharma B.C., Garg S., Kumar R., Sarin S.K. Endoscopic management of postoperative bile leaks. Hepatobiliary Pancreat. Dis. Int. 2006; 5 (12): 273–277.
17. Yi X.L., Li X.H., Wang J. Management of choledochoduodenal fistula. For All Health. 2012; 18: 66–67.
Supplementary files
Review
For citations:
Efremenkov A.M., Solodinina E.N., Zykin A.P., Fomicheva N.V. Choledochoduodenal fistula in a pediatric patient with gallstone disease. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2025;30(4):84-88. (In Russ.) https://doi.org/10.16931/1995-5464.2025-4-84-88
























