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Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery

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International consensus on diagnosing and managing pancreatic serous and mucinous cystic neoplasms

https://doi.org/10.16931/1995-5464.2025-3-12-30

Abstract

In 2023, with the approval of the leadership of the Hepato-Pancreato-Biliary Association of Commonwealth of Independent States, a consensus study was initiated and conducted on the diagnosis, management, and follow-up of patients with serous and mucinous neoplasms of the pancreas. Based on an extensive literature review, responses to each of the 22 questions posed were formulated and compiled into a Consensus Document. A total of 44 experts representing 27 institutions across 9 countries participated in the preparation of the Consensus. The Delphi method was employed for voting, and ultimately, including the results of votes on selected statements during the final conference, consensus was achieved on all questions.

About the Authors

I. E. Khatkov
Moscow Clinical Scientific Center named after A.S. Loginov; Russian University of Medicine; Moscow City Healthcare Department
Russian Federation

Igor E. Khatkov – Doct. of Sci. (Med.), Professor, Academician of the Russian Academy of Sciences, Director; Head of the Department of Faculty Surgery No. 2; Chief Oncology Specialist

86, sh. Entuziastov, Moscow, 111123

4, Dolgorukovskaya str., Moscow, 127006

43, bld. 1, Oruzheyny pereulok, Moscow, 127006



V. V. Tsvirkun
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Viktor V. Tsvirkun – Doct. of Sci. (Med.), Professor, Leading Researcher

86, sh. Entuziastov, Moscow, 111123



P. S. Tyutyunnik
Moscow Clinical Scientific Center named after A.S. Loginov; Russian Federation 2 Russian University of Medicine
Russian Federation

Pavel S. Tyutyunnik – Cand. of Sci. (Med.), Senior Researcher, Surgeon, Oncologist, Department of High-Tech Surgery and Surgical Endoscopy; Assistant of the Department of Faculty Surgery No. 2

 86, sh. Entuziastov, Moscow, 111123

4, Dolgorukovskaya str., Moscow, 127006



A. R.O. Aliev
National Oncology Center, Azerbaijan Republic Ministry of Health
Azerbaijan

Azer R. Aliyev – Doct. of Sci. (Med.), Head of the Abdominal Oncology Department, Oncologist

79B, G. Zardabi ave., Baku, AZ1122



S. M. Akhmadzoda
Research Institute of Gastroenterology of the Republic of Tajikistan
Tajikistan

Saidilhom M. Akhmadzoda – Doct. of Sci. (Med.), Professor, Head of the Clinical Department of the Academy of Medical Sciences of the Republic of Tajikistan; Head of the Department of Liver and Pancreas Surgery

2, Mayakovsky str., Dushanbe, 734025



I. G. Bakulin
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

Igor G. Bakulin – Doct. of Sci. (Med.), Professor, Dean of the Faculty of Medicine, Head of the Department of Propaedeutics of Internal Diseases, Gastroenterology and Dietetics named after S.M. Ryss

41, Kirochnaya str., St. Petersburg, 191015



B. B. Baimakhanov
National Scientific Center of Surgery named after A.N. Syzganov
Kazakhstan

Bolatbek B. Baimakhanov – Doct. of Sci. (Med.), Professor, Academician of the Russian Academy of Sciences, Corresponding Member of the National Academy of Sciences of the Republic of Kazakhstan, Director

62, Zheltoksan str., Almaty, 050004



B. Kh. Bebezov
Kyrgyz-Russian Slavic University named after B.N. Yeltsin
Kyrgyzstan

Bakhadyr Kh. Bebezov – Doct. of Sci. (Med.), Professor, Head of the Department of Hospital Surgery

44, Kievskaya str., Bishkek, 720000



N. A. Bodunova
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Natalia A. Bodunova – Doct. of Sci. (Med.), Head of the Center for Personalized Medicine, Head of the Moscow City Medical Genetic Center; Gastroenterologist

86, sh. Entuziastov, Moscow, 111123



D. S. Bordin
Moscow Clinical Scientific Center named after A.S. Loginov; 9 Tver State Medical University
Russian Federation

Dmitry S. Bordin – Doct. of Sci. (Med.), Head of the Department of Pathology of the Pancreas, Bile Tract and Upper Digestive Tract; Professor of the Department of General Medical Practice and Family Medicine

 86, sh. Entuziastov, Moscow, 111123

4, Sovetskaya str., Tver, Tver Region, 170100



I. M. Buriev
Hospital for War Veterans No. 3
Russian Federation

Ilya M. Buriev – Doct. of Sci. (Med.), Professor, Surgeon, Hospital for War Veterans No. 3

4, Startovaya str., Moscow, 129336



P. S. Vetshev
National Medical and Surgical Center named after N.I. Pirogov
Russian Federation

Petr S. Vetshev – Doct. of Sci. (Med.), Professor, Honored Doctor of the Russian Federation, Advisor on Clinical and Scientific Work, Honored Professor

70, Nizhnyaya Pervomaiskaya str., Moscow, 105203



S. L. Vorobiev
LLC “National Center for Clinical Morphological Diagnostics”
Russian Federation

Sergey L. Vorobiev – Cand. of Sci. (Med.), Director

32, Slavy ave., St. Petersburg, 192071



S. E. Voskanyan
Federal State Budgetary Institution “State Scientific Center of the Russian Federation – Federal Medical Biophysical Center named after A.I. Burnazyan” of the FMBA of Russia
Russian Federation

Sergey E. Voskanyan – Doct. of Sci. (Med.), Professor, Corresponding Member of the Russian Academy of Sciences, Deputy Chief Physician for Surgical Care, Head of Center for Surgery and Transplantation; Head of Department of Surgery with Courses in Oncology, Endoscopy, Surgical Pathology, Clinical Transplantology, and Organ Donation, Medical and Biological University of Innovation and Continuing Education

23, Marshal Novikov str., Moscow, 123098



V. A. Vishnevsky
Hepato-Pancreato-Biliary Association of Commonwealth of Independent States
Russian Federation

Vladimir A. Vishnevsky – Doct. of Sci. (Med.), Professor, President

27, str. Bolshaya Serpukhovskaya, Moscow, 115093



E. A. Dubtsova
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Elena A. Dubtsova – Doct. of Sci. (Med.), Head of the Department of Pancreatic and Biliary Pathologies

86, sh. Entuziastov, Moscow, 111123 



E. A. Dubova
Federal State Budgetary Institution “State Scientific Center of the Russian Federation – Federal Medical Biophysical Center named after A.I. Burnazyan” of the FMBA of Russia
Russian Federation

Elena A. Dubova – Doct. of Sci. (Med.), Pathologist

23, Marshal Novikov str., Moscow, 123098



V. I. Egorov
Ilyinsky Hospital; Academy of Postgraduate Education of the Federal State Budgetary Institution Federal Scientific and Clinical Center of the Federal Medical and Biological Agency of Russia
Russian Federation

Vyacheslav I. Egorov – Doct. of Sci. (Med.), Professor, Professor of the Department of Surgery with Courses in Oncosurgery, Endoscopy, Surgical Pathology, Clinical Transplantology and Organ Donation, Institute of Postgraduate Professional Education; Head of the Hepatopancreatobiliary Surgery Service

2, bld. 2, Rublevskoye Predmestie str., Glukhovo Village, Krasnogorsk, Moscow Region, 143421

91, Volokolamskoe sh., Moscow, 125371



M. G. Efanov
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Mikhail G. Efanov – Doct. of Sci. (Med.), Head of the Hepatopancreatobiliary Surgery Department

86, sh. Entuziastov, Moscow, 111123



V. E. Zagainov
Privolzhsky Research Medical University; Ministry of Health of the Nizhny Novgorod Region
Russian Federation

Vladimir E. Zagaynov – Doct. of Sci. (Med.), Head of the Department of Faculty Surgery and Transplantology; Chief Transplantologist

10/1, Minin and Pozharsky square, Nizhny Novgorod, 603005, Russian Federation

78A, Malaya Yamskaya str., Nizhny Novgorod, 603022



R. E. Izrailov
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Roman E. Izrailov – Doct. of Sci. (Med.), Associate Professor, Head of the Department of Innovative Surgery

86, sh. Entuziastov, Moscow, 111123



G. G. Karmazanovsky
A.V. Vishnevsky National Medical Research Center of Surgery; Sechenov First Moscow State Medical University (Sechenov University); All-Russian Public Organization for the Promotion of Development of Radiation Diagnostics and Therapy “Russian Society of Roentgenologists and Radiologists”
Russian Federation

Grigory G. Karmazanovsky – Doct. of Sci. (Med.), Professor, Academician of the Russian Academy of Sciences, Head of the Department of Radiation Diagnostics; Professor of the Department of Radiation Diagnostics, Institute of Professional Education; Vice President

27, Bolshaya Serpukhovskaya str., Moscow, 115093

8, Trubetskaya str., Moscow, 119991

18, bld. 2, Verkhoyanskaya str., Moscow, 129344



N. S. Karnaukhov
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Nikolay S. Karnaukhov – Cand. of Sci. (Med.), Head of the Pathological Anatomy Department, Pathologist

86, sh. Entuziastov, Moscow, 111123



V. L. Korobka
Rostov Regional Clinical Hospital
Russian Federation

Vyacheslav L. Korobka – Doct. of Sci. (Med.), Professor, Head Physician

170, Blagodatnaya str., Rostov-on-Don, 344015



A. G. Kotelnikov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Aleksey G. Kotelnikov – Doct. of Sci. (Med.), Professor, Leading Researcher of the Surgical Department of Liver and Pancreatic Tumors of the Research Institute of Clinical Oncology

23, Kashirskoe sh., Moscow, 115522



N. Yu. Kokhanenko
Saint Petersburg State Pediatric Medical University; Pokrovskaya City Hospital
Russian Federation

Nikolay Y. Kokhanenko – Doct. of Sci. (Med.), Professor, Head of the Department of Faculty Surgery; Surgeon

 2, Litovskaya str., St. Petersburg, 194100

85, pr. Bolshoy V.O., St. Petersburg, 199106



D. M. Krasilnikov
Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan; Kazan State Medical University
Russian Federation

Dmitry M. Krasilnikov – Doct. of Sci. (Med.), Professor, Head of the Department of Surgical Diseases; Chief Surgeon

138, Orenburgsky tract, Kazan, Republic of Tatarstan, 420064

49, Butlerova str., Kazan, 420012



A. G. Krieger
Russian Scientific Center of Roentgenoradiology
Russian Federation

Andrey G. Kriger – Doct. of Sci. (Med.), Professor, Chief Researcher of the Laboratory of Surgical Technologies in Oncology

86, Profsoyusnaya str., Moscow, 117997



Yu. V. Kulezneva
Moscow Clinical Scientific Center named after A.S. Loginov

Yulia V. Kulezneva – Doct. of Sci. (Med.), Head of the Department of Radiation Diagnostics and Treatment Methods; Professor of the Department of Faculty Surgery No. 2, Russian University of Medicine

 86, sh. Entuziastov, Moscow, 111123



T. N. Kuzmina
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Tatyana N. Kuzmina – Doct. of Sci. (Med.), Head of the Nutraceutical Laboratory

86, sh. Entuziastov, Moscow, 111123



K. A. Lesko
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Konstantin A. Lesko – Cand. of Sci. (Med.), Radiologist

86, sh. Entuziastov, Moscow, 111123



O. A. Malikhova
Russian Medical Academy of Continuous Professional Education; Hadassah Medical LTD
Russian Federation

Olga A. Malikhova – Doct. of Sci. (Med.), Professor of the Department of Oncology and Palliative Medicine; Leading Endoscopy Specialist

 2/1, bld. 1, Barrikadnaya str., Moscow, 125993

46, bld. 1, Bolshoy blvd., Moscow region, 143026



A. M. Mkrtumyan
Moscow Clinical Scientific Center named after A.S. Loginov; Russian University of Medicine
Russian Federation

Ashot M. Mkrtumyan – Doct. of Sci. (Med.), Professor, Head of the Endocrinology Department; Head of the Department of Endocrine and Metabolic Diseases

86, sh. Entuziastov, Moscow, 111123

4, Dolgorukovskaya str., Moscow, 127006



F. G. Nazyrov
Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov
Uzbekistan

Feruz G. Nazyrov – Doct. of Sci. (Med.), Professor, Academician of the Uzbek Academy of Sciences, Chairman of the Scientific Council

10 Kichik Khalka Yuli str., Tashkent, 100115



K. K. Noskova
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Karina K. Noskova – Cand. of Sci. (Med.), Head of the Clinical Diagnostic Laboratories

86, sh. Entuziastov, Moscow, 111123



O. V. Paklina
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Oksana V. Paklina – Doct. of Sci. (Med.), Professor, Scientific Consultant, Laboratory of Innovative Pathomorphology

86, sh. Entuziastov, Moscow, 111123



E. V. Parfenchikova
Moscow Clinical Scientific Center named after A.S. Loginov
Russian Federation

Elena V. Parfenchikova – Doct. of Sci. (Med.), Professor, Head of the Department of Diagnostic Endoscopy

86, sh. Entuziastov, Moscow, 111123



S. V. Petrov
Republican Clinical Oncology Dispensary
Russian Federation

Semyon V. Petrov – Doct. of Sci. (Med.), Professor, Pathologist, Head of the Laboratory of Immunohistochemical Diagnostics of Tumors

29, Sibirskiy trakt, Kazan, 420029



O. O. Rummo
State Institution “Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology”
Belarus

Oleg O. Rummo – Doct. of Sci. (Med.), Professor, Academician of the National Academy of Sciences of Belarus; Director

8, Semashko str., Minsk, 220087



E. N. Solodinina
Central Clinical Hospital of the Presidential Administration of the Russian Federation
Russian Federation

Elena N. Solodinina – Doct. of Sci. (Med.), Head of the Endoscopy Department

15, Marshal Timoshenko str., Moscow, 121359



Yu. A. Stepanova
A.V. Vishnevsky National Medical Research Center of Surgery
Russian Federation

Yulia A. Stepanova – Doct. of Sci. (Med.), Professor, Radiologist

27, Bolshaya Serpukhovskaya str., Moscow, 115093



S. A. Stepanyan
Mkhitar Heratsi Yerevan State Medical Institute; Mikaelyan Institute of Surgery; Ministry of Health of the Republic of Armenia
Armenia

Suren A. Stepanyan – Doct. of Sci. (Med.), Professor, Head of the Department of Surgery; Head of the Surgery Clinic; Advisor

2, Koryun str., Yerevan, 0025

9, Ezras Hasratyan str., Yerevan, 0052

3, Republic square, Government, Yerevan, 0010



V. G. Tedoradze
Batumi Republican Clinical Hospital
Georgia

Vazha G. Tedoradze – Doct. of Sci. (Med.), Head of the Surgery Department, Deputy Director for Science

2, Yavakashvili str., Batumi, 6000



A. V. Shabunin
Moscow City Healthcare Department; Russian Medical Academy of Continuous Professional Education; Botkin Hospital
Russian Federation

Aleksey V. Shabunin – Doct. of Sci. (Med.), Professor, Academician of the Russian Academy of Sciences, Director; Head of the Department of Surgery; Chief Surgeon and Endoscopist

43, bld. 1, Oruzheyny pereulok, Moscow, 127006

2/1, bld. 1, Barrikadnaya str., Moscow, 125993

5, 2nd Botkinsky proezd, Moscow, 125284



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Khatkov I.E., Tsvirkun V.V., Tyutyunnik P.S., Aliev A.R., Akhmadzoda S.M., Bakulin I.G., Baimakhanov B.B., Bebezov B.Kh., Bodunova N.A., Bordin D.S., Buriev I.M., Vetshev P.S., Vorobiev S.L., Voskanyan S.E., Vishnevsky V.A., Dubtsova E.A., Dubova E.A., Egorov V.I., Efanov M.G., Zagainov V.E., Izrailov R.E., Karmazanovsky G.G., Karnaukhov N.S., Korobka V.L., Kotelnikov A.G., Kokhanenko N.Yu., Krasilnikov D.M., Krieger A.G., Kulezneva Yu.V., Kuzmina T.N., Lesko K.A., Malikhova O.A., Mkrtumyan A.M., Nazyrov F.G., Noskova K.K., Paklina O.V., Parfenchikova E.V., Petrov S.V., Rummo O.O., Solodinina E.N., Stepanova Yu.A., Stepanyan S.A., Tedoradze V.G., Shabunin A.V. International consensus on diagnosing and managing pancreatic serous and mucinous cystic neoplasms. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2025;30(3):12-30. (In Russ.) https://doi.org/10.16931/1995-5464.2025-3-12-30

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ISSN 1995-5464 (Print)
ISSN 2408-9524 (Online)