Evolution of views and modern concepts of the state of the hemostasis system in liver cirrhosis
https://doi.org/10.16931/1995-5464.20211107-114
Abstract
Aim. To study the state of individual elements of the hemostasis system in liver cirrhosis according to modern literature.
Summary. The review presents an analysis of literature data covering the state of the homeostasis system in liver cirrhosis. The pathophysiological and pathogenetic mechanisms that underlie the disorders that occur in various parts of the hemostatic system in this pathology are described in a polemical style. Literature data concerning a relatively littlestudied aspect of cirrhosis – hypercoagulation are analyzed. From the standpoint of modern concepts and taking into account the peculiarities of hemostasis disorders, the pathogenetic significance of the vascular endothelium and endothelial dysfunction is postulated. As well as the role of inflammatory mediators in the development of coagulopathy and intravascular coagulation syndrome in patients with cirrhosis of the liver.
About the Authors
S. A. Aliyev
Azerbaijan Medical University
Azerbaijan
Azerbaijan
Saday A. Aliyev – Doct. of Sci. (Med.), Professor of the Department of Surgical Diseases No. 1
23, Bakıkhanov str., Baku, AZ 1002,
E. S. Aliyev
Azerbaijan Medical University
Azerbaijan
Azerbaijan
Emil S. Aliyev – Cand. of Sci. (Med.), Resident of the Department of Surgical Diseases No. 1
23, Bakıkhanov str., Baku, AZ 1002,
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For citations:
Aliyev S.A., Aliyev E.S. Evolution of views and modern concepts of the state of the hemostasis system in liver cirrhosis. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2021;26(1):107-114. (In Russ.) https://doi.org/10.16931/1995-5464.20211107-114
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