Preview

Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery

Advanced search

Simultaneous transoral parathyroidectomy and laparoscopic pancreatic resection in type 1 Multiple Endocrine Neoplasia syndrome

https://doi.org/10.16931/1995-5464.2021-4-126-132

Abstract

The article presents a clinical observation of a patient with type 1 Multiple Endocrine Neoplasia syndrome (MEN 1). During the diagnostic search, a combination of primary hyperparathyroidism, parathyroid adenoma and hormonally inactive pancreatic head tumor was found. Simultaneous transoral parathyroidectomy and laparoscopic resection of the pancreatic head was performed. We haven`t found the literature data describing such kind of operations for MEN 1 syndrome. An original solution was applied to perform intraoperative ultrasonography monitoring. The results of 1-year postoperative follow-up are presented. This observation demonstrates the possibilities of endoscopic technologies in the treatment of MEN 1 syndrome.

About the Authors

S. E. Gryaznov
City Clinical Hospital No. 4, Moscow Healthcare Department
Russian Federation

Sergey E. Gryaznov – Surgeon, Oncologist

25, Pavlovskaia str., Moscow, 115093, Phone: 8-916-299-26-88



I. M. Buriev
City Clinical Hospital No. 4, Moscow Healthcare Department
Russian Federation

Ilya M. Buriev – Doct. of Sci. (Med.), Professor, Surgeon, Oncologist

25, Pavlovskaia str., Moscow, 115093



G. G. Melkonyan
City Clinical Hospital No. 4, Moscow Healthcare Department; Russian Medical Academy of Continuous Professional Education of the Ministry of Health of Russia
Russian Federation

Georgy G. Melkonyan – Doct. of Sci. (Med.), Professor of the Department of Surgery, Russian Medical Academy of Continuous Professional Education of the Ministry of Health of Russia; Chief  Physician of the City Clinical Hospital No. 4 of the Moscow Healthcare Department

25, Pavlovskaia str., Moscow, 115093

bld. 1, 2/1, Barricadnaya str., Moscow, 125993



N. S. Malyuga
City Clinical Hospital No. 4, Moscow Healthcare Department
Russian Federation

Natalya S. Malyuga – Head of the Department of Ultrasound Diagnostics

25, Pavlovskaia str., Moscow, 115093



B. K. Laypanov
City Clinical Hospital No. 4, Moscow Healthcare Department
Russian Federation

Boris K. Laipanov – Cand. of Sci. (Med.), Surgeon

25, Pavlovskaia str., Moscow, 115093



References

1. Giusti F., Marini F., Brandi M.L. Multiple Endocrine Neoplasia Type 1. 2005 Aug 31 [updated 2017 Dec 14]. In: Adam M.P., Ardinger H.H., Pagon R.A., Wallace S.E., Bean L.J.H., Stephens K., Amemiya A., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2020. PMID: 20301710.

2. Kriger A.G., Kochatkov A.V., Gorin D.S., Lebedeva A.N. Endocrine pancreatic tumors by type I syndrome of multiple endocrine neoplasia. Pirogov Russian Journal of Surgery = Khirurgiya. Zhurnal imeni N.I. Pirogova. 2010; (8): 69–75. (In Russian)

3. Vergès B., Boureille F., Goudet P., Murat A., Beckers A., Sassolas G., Cougard P., Chambe B., Montvernay C., Calender A. Pituitary disease in MEN type 1 (MEN1): data from the France-Belgium MEN1 multicenter study. J. Clin. Endocrinol. Metab. 2002; 87 (2): 457–465. https://doi.org/10.1210/jcem.87.2.8145

4. Schreinemakers J.M., Pieterman C.R., Scholten A., Vriens M.R., Valk G.D., Rinkes I.H. The optimal surgical treatment for primary hyperparathyroidism in MEN1 patients: a systematic review. World J. Surg. 2011; 35 (9): 1993–2005. https://doi.org/10.1007/s00268-011-1068-9

5. Manoharan J., Albers M.B., Bollmann C., Maurer E., Mintziras I., Wächter S., Bartsch D.K. Single gland excision for MEN1-associated primary hyperparathyroidism. Clin. Endocrinol. (Oxf.). 2020; 92 (1): 63–70. https://doi.org/10.1111/cen.14112

6. Horiuchi K., Sakurai M., Haniu K., Nagai E., Tokumitsu H., Yoshida Y., Omi Y., Sakamoto A., Okamoto T. Impact of "tailored" parathyroidectomy for treatment of primary hyperparathyroidism in patients with multiple endocrine neoplasia type 1. World J. Surg. 2018; 42 (6): 1772–1778. https://doi.org/10.1007/s00268-017-4366-z

7. Kiernan C.M., Grubbs E.G. Surgical management of multiple endocrine neoplasia 1 and multiple endocrine neoplasia 2. Surg. Clin. North Am. 2019; 99 (4): 693–709. https://doi.org/10.1016/j.suc.2019.04.015

8. Jensen R.T., Norton J.A. Treatment of pancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1: some clarity but continued controversy. Pancreas. 2017; 46 (5): 589–594. https://doi.org/10.1097/MPA.0000000000000825

9. Falconi M., Eriksson B., Kaltsas G., Bartsch D.K., Capdevila J., Caplin M., Kos-Kudla B., Kwekkeboom D., Rindi G., Klöppel G., Reed N., Kianmanesh R., Jensen R.T. ENETS Consensus Guidelines Update for the management of patients with functional pancreatic neuroendocrine tumors and non-functional pancreatic neuroendocrine tumors. Neuroendocrinology. 2016; 103 (2): 153–171. https://doi.org/10.1159/000443171

10. Yang G., Ji M., Chen J., Chen R., Chen Y., Fu D., Hou B., Huang H., Jiang L., Jin K., Ke N., Li Y., Li Y., Liang H., Liu A., Luo J., Ni Q., Shao C., Shen B., Sheng W., Song B., Sun J., Tan C., Tan H., Tang Q., Tang Y., Tian X., Wang J., Wang J., Wang W., Wang W., Wu Z., Xu J., Yan Q., Yang N., Yang Y., Yin X., Yu X., Yuan C., Zeng S., Zhang G., Zhang R., Zhou Z., Zhu Z., Shao C. Surgery management for sporadic small (≤2 cm), non-functioning pancreatic neuroendocrine tumors: a consensus statement by the Chinese Study Group for Neuroendocrine Tumors (CSNET). Int. J. Oncol. 2017; 50 (2): 567–574. https://doi.org/10.3892/ijo.2016.3826

11. Concolino P., Costella A., Capoluongo E. Multiple endocrine neoplasia type 1 (MEN1): An update of 208 new germline variants reported in the last nine years. Cancer Genet. 2016; 209 (1–2): 36–41. https://doi.org/10.1016/j.cancergen.2015.12.002

12. Ignatyuk V.G., Britvin T.A., Podrez D.V., Gurevich L.E. Multiple endocrine neoplasia type 1 with primary hyperparathyroidism, pancreatic insulinoma and portal gastrinoma (case report). Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2018; 23 (3): 57–63. https://doi.org/10.16931/1995-5464.2018357-63 (In Russian)

13. Hou B., Tang W., Su X., Liu W. [Successful simultaneous surgery for patient with insulinoma and parathyroid adenoma relevant to multiple endocrine neoplasia type 1: A case report]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019; 44 (9): 1083–1088. Chinese. https://doi.org/10.11817/j.issn.1672-7347.2019.190601


Supplementary files

Review

For citations:


Gryaznov S.E., Buriev I.M., Melkonyan G.G., Malyuga N.S., Laypanov B.K. Simultaneous transoral parathyroidectomy and laparoscopic pancreatic resection in type 1 Multiple Endocrine Neoplasia syndrome. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2021;26(4):126-132. (In Russ.) https://doi.org/10.16931/1995-5464.2021-4-126-132

Views: 404


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1995-5464 (Print)
ISSN 2408-9524 (Online)