Modern approaches to surgical treatment of patients with colorectal cancer liver metastases
https://doi.org/10.16931/1995-5464.2022-1-80-86
Abstract
Hepatic resection has become the treatment of choice for metastatic colorectal cancer, and this treatment technique increases the five-year survival of cancer patients up to 40–58%. More recently, the criteria for resectability have been revised and expanded to include any patient in whom all metastatic deposits can be removed with a negative surgical margin and with sufficient residual liver parenchyma. Currently, resectability is determined mostly by the minimum functional liver remnant volume. Under this new paradigm, the number of patients with potentially resectable oncological process can be increased. However, there are no widely accepted concepts and criteria for resectability, which further complicates the choice of treatment methods and directly affects the patients’ survival. The literature search for this review was performed using PubMed, Cochrane Library, Google Scholar, and eLibrary systems. We included publications that characterized the modern possibilities of liver surgery aimed at increasing resectability and improving cancer outcomes in patients with colorectal cancer liver metastases.
About the Authors
A. Y. Dobrodeev
Cancer Research Institute, Tomsk National Research Medical Center (NRMC) of the Russian Academy of Sciences,Tomsk
Russian Federation
Russian Federation
Alexey Yu. Dobrodeev – Doct. of Sci. (Med.), Leading Researcher, Department of Abdominal Oncology
5, Kooperativny per., Tomsk, 634009
D. N. Kostromitsky
Cancer Research Institute, Tomsk National Research Medical Center (NRMC) of the Russian Academy of Sciences,Tomsk
Russian Federation
Russian Federation
Dmitry N. Kostromitsky – Cand. of Sci. (Med.), Researcher, Department of Abdominal Oncology
5, Kooperativny per., Tomsk, 634009
S. G. Afanasyev
Cancer Research Institute, Tomsk National Research Medical Center (NRMC) of the Russian Academy of Sciences,Tomsk
Russian Federation
Russian Federation
Sergey G. Afanasyev – Doct. of Sci. (Med.), Professor, Head of the Department of Abdominal Oncology
5, Kooperativny per., Tomsk, 634009
A. S. Tarasova
Cancer Research Institute, Tomsk National Research Medical Center (NRMC) of the Russian Academy of Sciences,Tomsk
Russian Federation
Russian Federation
Anna S. Tarasova – Cand. of Sci. (Med.), Researcher, Department of Abdominal Oncology
5, Kooperativny per., Tomsk, 634009
A. V. Avgustinovich
Cancer Research Institute, Tomsk National Research Medical Center (NRMC) of the Russian Academy of Sciences,Tomsk
Russian Federation
Russian Federation
Aleksandra V. Avgustinovich – Cand. of Sci. (Med.), Senior Researcher, Department of Abdominal Oncology
5, Kooperativny per., Tomsk, 634009
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For citations:
Dobrodeev A.Y., Kostromitsky D.N., Afanasyev S.G., Tarasova A.S., Avgustinovich A.V. Modern approaches to surgical treatment of patients with colorectal cancer liver metastases. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2022;27(1):80-86. (In Russ.) https://doi.org/10.16931/1995-5464.2022-1-80-86
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