Isolated cavaportal hepatic chemoperfusion using melphalan in the treatment of uveal melanoma liver metastases
A. D. Kaprin,
S. A. Ivanov,
V. M. Unguryan,
L. O. Petrov,
V. V. Nazarova,
U. A. Pobedintseva,
N. A. Falaleeva,
E. A. Kruglov,
K. V. Orlova,
A. G. Isaeva,
E. V. Filimonov https://doi.org/10.16931/1995-5464.2022-2-115-120
Abstract
A rare clinical observation of using hyperthermic isolated hepatic chemoperfusion is considered in the setting of a pathologically altered hepatic arterial blood flow in focal hepatic lesions caused by uveal melanoma metastases. The technical feasibility and safety of performing hyperthermic isolated hepatic chemoperfusion through the portal vein against the background of the altered hepatic arterial bed were demonstrated.
About the Authors
A. D. Kaprin
National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Andrey D. Kaprin – Doct. of Sci. (Med.), Professor, Russian Academy of Sciences (RAS) full member, Director General
4, Korolev str., Obninsk, 249036
S. A. Ivanov
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Sergey A. Ivanov – Doct. of Sci. (Med.), Professor of the RAS, Director
4, Korolev str., Obninsk, 249036
V. M. Unguryan
Kostroma Regional Oncology Center
Vladimir M. Unguryan – Cand. of Sci. (Med.), Chief Doctor
19, Nizhnyaya Debrya, Kostroma, 156005
L. O. Petrov
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Leonid O. Petrov – Cand. of Sci. (Med.), Chief of Abdominal Oncology Department
4, Korolev str., Obninsk, 249036
V. V. Nazarova
N.N. Blokhin Scientific Research Center for Oncology, Ministry of Health of the Russian Federation
Valeriya V. Nazarova – Cand. of Sci. (Med.), Oncologist of the Department of Oncodermatology
23, Kashirskoe shosse, Moscow, 115478
U. A. Pobedintseva
Kostroma Regional Oncology Center
Yuliya A. Pobedintseva – Deputy Chief Doctor for Anesthesiology and Intensive Care
19, Nizhnyaya Debrya, Kostroma, 156005
N. A. Falaleeva
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Natalya A. Falaleeva – Doct. of Sci. (Med.), Head of the Department for the Medical Treatment of Malignancies
4, Korolev str., Obninsk, 249036
E. A. Kruglov
Kostroma Regional Oncology Center
Egor A. Kruglov – Head of Oncology Department for Surgical Treatment Methods No. 1
19, Nizhnyaya Debrya, Kostroma, 156005
K. V. Orlova
N.N. Blokhin Scientific Research Center for Oncology, Ministry of Health of the Russian Federation
Kristina V. Orlova – Cand. of Sci. (Med.), Senior Researcher, Oncodermatology Department
23, Kashirskoe shosse, Moscow, 115478
A. G. Isaeva
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Aisha G. Isaeva – Cand. of Sci. (Med.), Senior Researcher, Department of Radiation and Surgical Treatment for Abdominal Diseases
4, Korolev str., Obninsk, 249036
E. V. Filimonov
Kostroma Regional Oncology Center
Evgeniy V. Filimonov – Head of the Anesthesiology and Intensive Care Unit
19, Nizhnyaya Debrya, Kostroma, 156005
References
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Supplementary files
Review
For citations:
Kaprin A.D., Ivanov S.A., Unguryan V.M., Petrov L.O., Nazarova V.V., Pobedintseva U.A., Falaleeva N.A., Kruglov E.A., Orlova K.V., Isaeva A.G., Filimonov E.V. Isolated cavaportal hepatic chemoperfusion using melphalan in the treatment of uveal melanoma liver metastases. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2022;27(2):115-120. (In Russ.) https://doi.org/10.16931/1995-5464.2022-2-115-120
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