Роль бактериохолии в развитии инфекционных осложнений панкреатодуоденальной резекции

Частота инфекционных осложнений после панкреатодуоденальной резекции остается значительной. Бактериохолия у этой категории больных с высокой частотой развивается в результате предоперационного билиарного дренирования. Ее роль в развитии инфекции области хирургического вмешательства и методы воздействия на нее изучены недостаточно. Представлен анализ отечественной и зарубежной литературы, рассмотрена роль бактериохолии в развитии инфекции области хирургического вмешательства после панкреатодуоденальной резекции. Бактериохолия представляется одним из наиболее значимых факторов инфекции области хирургического вмешательства после этой операции. Бактериальная культура в интраоперационно полученном образце желчи и микробиом области хирургического вмешательства представлены патогенами, резистентными к стандартным препаратам, применяемым для периоперационной антибиотикопрофилактики. Для уменьшения частоты инфекционных осложнений в области хирургического вмешательства после панкреатодуоденальной резекции необходим дальнейший поиск методов воздействия на бактериохолию, в том числе пересмотр подходов к периоперационному назначению антибактериальных средств.

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