Role of bacteriocholia in development of infectious complications of pancreaticoduodenal resection
R. V. Kursenko,
A. A. Trushin,
D. A. Zaitsev,
I. V. Vervekin,
A. A. Svechkova,
M. A. Belyaev,
A. А. Zaharenko https://doi.org/10.16931/1995-5464.2022-4-117-124
Abstract
The incidence of infectious complications after pancreaticoduodenal resection remains significant. High frequency of bacteriocholia in this category of patients is a result of preoperative biliary drainage. The role of bacteriocholia in the development of surgical site infection and the methods of exposure to it are yet to be studied. The authors presented the analysis of Russian and foreign literature and considered the role of bacteriocholia in the development of surgical site infection after pancreaticoduodenal resection. Bacteriocholia appears to be one of the most significant factors in the surgical site infection after this kind of resection. Bacterial cultures in the intraoperative bile sample and the surgical microbiome are represented by pathogens resistant to standard drugs used for perioperative antibiotic prophylaxis. In order to decrease the incidence of surgical site infections after the pancreaticoduodenal resection it is essential to continue searching for the methods of exposure to bacteriocholia including revision of the approaches to perioperative administration of antibacterial agents.
About the Authors
R. V. Kursenko
Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation
Russian Federation
Russian Federation
Roman V. Kursenko – Surgeon, Oncology Department №1, Research Institute for Surgery and Emergency Medicine, Oncology Department №1
6-8, L'va Tolstogo str., St. Petersburg, 197022
Phone: +7-965-082-14-27
A. A. Trushin
Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation
Russian Federation
Russian Federation
Anton A. Trushin – Head of Oncology Department №1, Research Institute for Surgery and Emergency Medicine
6-8, L'va Tolstogo str., St. Petersburg, 197022
D. A. Zaitsev
Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation
Russian Federation
Russian Federation
Danila A. Zaitsev – Surgeon, Surgical Department №4, Research Institute for Surgery and Emergency Medicine
6-8, L'va Tolstogo str., St. Petersburg, 197022
I. V. Vervekin
Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation
Russian Federation
Russian Federation
Ilya V. Vervekin – Resident Physician, Department of Oncology
6-8, L'va Tolstogo str., St. Petersburg, 197022
A. A. Svechkova
Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation
Russian Federation
Russian Federation
Anna A. Svechkova – Resident Physician, Department of Faculty Surgery with courses in Laparoscopic and Cardio vascular Surgery
6-8, L'va Tolstogo str., St. Petersburg, 197022
M. A. Belyaev
Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation
Russian Federation
Russian Federation
Mihail A. Belyaev – Cand. of Sci. (Med.), Head of the Oncology Department №1, Research Institute for Surgery and Emergency Medicine
6-8, L'va Tolstogo str., St. Petersburg, 197022
A. А. Zaharenko
Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation
Russian Federation
Russian Federation
Aleksandr A. Zaharenko – Doct. of Sci. (Med.), Head of the Department of Oncosurgery, Research Institute for Surgery and Emergency Medicine
6-8, L'va Tolstogo str., St. Petersburg, 197022
References
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For citations:
Kursenko R.V., Trushin A.A., Zaitsev D.A., Vervekin I.V., Svechkova A.A., Belyaev M.A., Zaharenko A.А. Role of bacteriocholia in development of infectious complications of pancreaticoduodenal resection. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2022;27(4):117-124. (In Russ.) https://doi.org/10.16931/1995-5464.2022-4-117-124
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