CYSTIC TRANSFORMATION OF NEUROENDOCRINE TUMORS

Cystous transformation of pancreatic  neuroendocrine tumor  (NET)  is rare. It is caused by development  of secondary hemorrhages and necroses in large tumors. Necroses in NET are colliquative and the results of local violation of blood supply in tumor.  One  of outcomes  of tumoral  necrosis  or hemorrhage  is formation  of cyst due  to  local action  of macrophages  who lysis the necrosis fabrics and blood clots. Such mechanism  of tumor  transformation specifies that predominantly nonfunctioning asymptomatic  NET of large sizes are exposed to necrosis and following cystic transformation. It is presented clinical case of cystic transformation of pancreatic NET in 53 years old woman who didn't have any specific complaints. Difficulties of preoperative diagnostics were caused by fact that the solid part of tumor was expressed by insignificant hypervascular parietal component.

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