Laparoscopic Approach in Liver Harvesting from Living Donors for Transplantation in Children
https://doi.org/10.16931/1995-5464.2018-1-13-18
Abstract
Aim. To analyze own experience of laparoscopic liver resection in living donors and to compare our results with the experience of world leading centers.
Material and Methods. In our center 32 laparoscopic liver resections for transplantation to pediatric patients have been performed since May 2016 to October 2017. Left lateral sector resection was performed in 31 cases, left-sided hemihepatectomy – in one case.
Results. Mean age of donors was 28.61 (±5.84) years, mean intraoperative blood loss – 93.87 (± 50) ml, time of surgery – 276 (±44) min, length of hospital-stay – 4 (± 1.12) days. There were no complications Clavien–Dindo grade II and over.
Conclusion. Laparoscopic liver resection in adult donors for transplantation to pediatric patients is followed by qualitative graft and facilitates rapid rehabilitation of living donor.
About the Authors
S. V. GautierRussian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
Doct. of Med. Sci., Professor, Director of Shumakov National Medical Research Center for Transplantation and Artificial Organs, Academician of the Russian Academy of Sciences, Chief Transplantologist of Healthcare Ministry of Russia, Head of the Chair of Transplantation and Artificial Organs of the Sechenov University
A. R. Monakhov
Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
Phone: +7-906-078-16-21
Cand. of Med. Sci., Head of the Surgical Department No.2 of Shumakov National Medical Research Center for Transplantation and Artificial Organs, Assistant of the Chair of Transplantation and Artificial Organs of the Sechenov University
E. A. Gallyamov
Russian Federation
7, Ivankovskoe shosse, Moscow, 125367, Russian Federation
Doct. of Med. Sci., Professor of the Chair of Surgery No.1 of Yevdokimov Moscow State University of Medicine and Dentistry
E. V. Zagaynov
Russian Federation
86, shosse Enthusiastov, Moscow, 111123, Russian Federation
Surgeon at the Loginov Clinical Scientific Center of Moscow Healthcare Department
O. M. Tsirulnikova
Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
Doct. of Med. Sci., Professor of the Chair of Transplantation and Artificial Organs of the Sechenov University
K. O. Semash
Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
Resident Surgeon of the Surgical Department No.2 of Shumakov National Medical Research Center for Transplantation and Artificial Organs
T. A. Dzhanbekov
Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
Cand. of Med. Sci., Surgeon of the Surgical Department No.2 of Shumakov National Medical Research Center for Transplantation and Artificial Organs
Kh. M. Khizroev
Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
Cand. of Med. Sci., Senior Researcher of the Surgical Department No.2 of Shumakov National Medical Research Center for Transplantation and Artificial Organs
D. O. Oleshkevich
Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
Resident Surgeon of the Surgical Department No.2 of Shumakov National Medical Research Center for Transplantation and Artificial Organs
E. V. Chekletsova
Russian Federation
1, Shchukinskaya str., Moscow, 123182, Russian Federation
Cand. of Med. Sci., Pediatrician of the Clinical and Diagnostic Department of Shumakov National Medical Research Center for Transplantation and Artificial Organs
References
1. Strong R.W., Lynch S.V., Ong T.H., Matsunami H., Koido Y., Balderson G.A. Successful liver transplantation from a living donor to her son. N. Engl. J. Med. 1990; 322 (21): 1505–1507.
2. Fine R.N., Webber S.A., Harmon W.E., Kelly D.A., Olthoff K.M. (eds.). Pediatric solid organ transplantation. JohnWiley&Sons, 2007. 470 p.
3. Miller C.M. Ethical dimensions of living donation: experience with living liver donation. Transplant. Rev. 2008; 22 (3): 206–209. DOI: 10.1016/j.trre.2008.02.001.
4. Iwasaki J., Iida T., Mizumoto M., Uemura T., Yagi S., Hori T., Uemoto S. Donor morbidity in right and left hemiliver living donor liver transplantation: the impact of graft selection and surgical innovation on donor safety. Transplant. Internat. 2014; 27 (11): 1205–1213. DOI: 10.1111/tri.12414.
5. Cherqui D., Soubrane O., Husson E., Barshasz E., Vignaux O., Ghimouz M., Houssin D. Laparoscopic living donor hepatectomy for liver transplantation in children. Lancet. 2002; 359 (9304): 392–396. DOI: 10.1016/S0140-6736(02)07598-0.
6. Koffron A.J., Kung R., Baker T., Fryer J., Clark L., Abecassis M. Laparoscopic- assisted right lobe donor hepatectomy. Am. J. Transplant. 2006; 6 (10): 2522–2525. DOI: 10.1111/j.1600-6143.2006.01498.x.
7. Wakabayashi G., Nitta H., Takahara T., Shimazu M., Kitajima M., Sasaki A. Standardization of basic skills for laparoscopic liver surgery towards laparoscopic donor hepatectomy. J. Hepatobiliary Pancreat. Surg. 2009; 16 (4): 439–444. DOI: 10.1007/s00534-009-0122-6.
8. Giulianotti P.C., Tzvetanov I., Jeon H., Bianco F., Spaggiari M., Oberholzer J., Benedetti E. Robot-assisted right lobe donor hepatectomy. Transplant. International. 2012; 25 (1). DOI: 10.1111/j.1432-2277.2011.01373.x.
9. Soubrane O., Perdigao Cotta F., Scatto O. Pure laparoscopic right hepatectomy in a living donor. Am. J. Transplant. 2013; 13 (9): 2467–2471. DOI: 10.1111/ajt.12361.
10. Rotellar F., Pardo F., Benito A., Martí-Cruchaga P., Zozaya G., Lopez L., Herrero I. Totally laparoscopic right-lobe hepatectomy for adult living donor liver transplantation: useful strategies to enhance safety. Am. J. Transplant. 2013; 13 (12): 3269–3273. DOI: 10.1111/ajt.12471.
11. Han H.S., Cho J.Y., Yoon Y.S., Hwang D.W., Kim Y.K., Shin H.K., Lee W. Total laparoscopic living donor right hepatectomy. Surg. Endosc. 2015; 29 (1): 184. DOI: 10.1007/s00464-014-3649-9.
12. Gautier S.V., Gallyamov E.A., Monakhov A.R., Zagainov E.V. Laparoscopic left- sided lateral segmentectomy in living donor. Vestnik transplantologii i iskusstvennyh organov. 2016; 18 (4): 50–55. DOI: 10.15825/1995-1191-2016-4-43-55. (In Russian)
13. National Center for Biotechnology Information [электронный ресурс] https://www.ncbi.nlm.nih.gov/pubmed/ (дата обращения 07.11.17).
14. Soubrane O., Cherqui D., Scatton O., Stenard F., Bernard D., Branchereau S., Martelli H., Gauthier F. Laparoscopic left lateral sectionectomy in living donors: safety and reproducibility of the technique in a single center. Ann. Surg. 2006; 244 (5): 815–820. DOI: 10.1097/01.sla.0000218059.31231.b6.
15. Kim K.H., Jung D.H., Park K.M., Lee Y.J., Kim D.Y., Kim K.M., Lee S.G. Comparison of open and laparoscopic live donor left lateral sectionectomy. Br. J. Surg. 2011; 98 (9): 1302–1308. DOI: 10.1002/bjs.7601.
16. Samstein B., Griesemer A., Cherqui D., Mansour T., Pisa J., Yegiants A., Emond J. Fully laparoscopic left sided donor hepatectomy is safe and associated with horter hospital stay and earlier return to work: A comparative study. Liver Transpl. 2015; 21 (6): 768–773. DOI: 10.1002/lt.24116.
17. Yu Y.D., Kim K.H., Jung D.H., Lee S.G., Kim Y.G., Hwang G.S. Laparoscopic live donor left lateral sectionectomy is safe and feasible for pediatric living donor liver transplantation. Hepatogastroenterology. 2012; 59 (120): 2445–2449. DOI: 10.5754/hge12134.
18. Scatton O., Katsanos G., Boillot O., Goumard C., Bernard D., Stenard F., Soubrane O. Pure laparoscopic left lateral sectionectomy in living donors: from innovation to development in France. Ann. Surg. 2015; 261 (3): 506–512. DOI: 10.1097/SLA.0000000000000642.
19. Troisi R.I., Berardi G. Laparoscopic left lateral sectionectomy for living liver donation: the Ghent University experience. Ann. Laparosc. Endosc. Surg. 2017; 2 (1). DOI: 10.21037/ales.2017.04.09.
Review
For citations:
Gautier S.V., Monakhov A.R., Gallyamov E.A., Zagaynov E.V., Tsirulnikova O.M., Semash K.O., Dzhanbekov T.A., Khizroev Kh.M., Oleshkevich D.O., Chekletsova E.V. Laparoscopic Approach in Liver Harvesting from Living Donors for Transplantation in Children. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2018;23(1):13-18. (In Russ.) https://doi.org/10.16931/1995-5464.2018-1-13-18