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Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery

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The choice of local destruction method of colorectal cancer liver metastases

https://doi.org/10.16931/1995-5464.2019430-36

Abstract

Aim: to improving the treatment outcomes, quality and life expectancy, prognosis in patients with colorectal liver metastases.
Materials and methods. The long-term results of the treatment of 94 patients with colorectal cancer liver metastases (2014–2019) were analyzed. In 87 cases (92.6%) various surgical procedures were performed. Segmentectomy was performed in 23 patients, segmentectomy with radiofrequency ablation – 7, segmentectomy with cryoablation – 3, segmentectomy with radiofrequency ablation and cryoablation – 3. Also, hemihepatectomy was performed in 15 patients, extended hemihepatectomy – 13, hemihepatectomy with radiofrequency ablation – 1. Radiofrequency ablation and cryoablation were performed in 8 cases, transarterial chemoembolization in 12 cases. The average age of the patients was 56.3 ± 3 years. All patients subsequently underwent adjuvant chemotherapy. In 9 case the regional chemoembolization was added.
Results. Postoperative morbidity was 30 cases (34.5%) in the immediate postoperative period. Actuarial survival in the patients undergoing surgery was 1 year – 63%, 3 years – 34% and 5 years – 28%.
Conclusion. A differentiated approach in local destruction of colorectal liver metastases allows satisfactory long-term results in multiple bilobar lesions. The key to success is a multidisciplinary approach to treatment.

About the Authors

A. V. Chzhao
Vishnevsky National Medical Research Center of Surgery
Russian Federation
Doct. of Sci. (Med.), Professor, Deputy Director

27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation



V. A. Vishnevsky
Vishnevsky National Medical Research Center of Surgery
Russian Federation
Doct. of Sci. (Med.), Professor

27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation



D. A. Ionkin
Vishnevsky National Medical Research Center of Surgery
Russian Federation
Cand. of Sci. (Med.), Surgeon of the Oncology Department

27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation



A. A. Olifir
Vishnevsky National Medical Research Center of Surgery
Russian Federation
Graduate Student of the Oncology Department
 27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
Phone: 8-926-369-31-76




X. A. Ayvazyan
Vishnevsky National Medical Research Center of Surgery
Russian Federation
Resident of the Oncology Department

27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation



Yu. A. Kovalenko
Vishnevsky National Medical Research Center of Surgery
Russian Federation
Cand. of Sci. (Med.), Senior Researcher of the Oncology Department

27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation



O. I. Zhavoronkova
Vishnevsky National Medical Research Center of Surgery
Russian Federation
Cand. of Sci. (Med.), Functional Diagnostics Physician

27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation



Yu. A. Stepanova
Vishnevsky National Medical Research Center of Surgery
Russian Federation
Doct. of Sci. (Med.), Senior Researcher, Physician of the Ultrasound Diagnostics Department

27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation



N. A. Karelskaya
Vishnevsky National Medical Research Center of Surgery
Russian Federation

Cand. of Sci. (Med.), Physician of the Department of Radiology and Magnetic Resonance Imaging

27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation




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Review

For citations:


Chzhao A.V., Vishnevsky V.A., Ionkin D.A., Olifir A.A., Ayvazyan X.A., Kovalenko Yu.A., Zhavoronkova O.I., Stepanova Yu.A., Karelskaya N.A. The choice of local destruction method of colorectal cancer liver metastases. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2019;24(4):30-36. (In Russ.) https://doi.org/10.16931/1995-5464.2019430-36

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ISSN 1995-5464 (Print)
ISSN 2408-9524 (Online)