The choice of local destruction method of colorectal cancer liver metastases
https://doi.org/10.16931/1995-5464.2019430-36
Abstract
Materials and methods. The long-term results of the treatment of 94 patients with colorectal cancer liver metastases (2014–2019) were analyzed. In 87 cases (92.6%) various surgical procedures were performed. Segmentectomy was performed in 23 patients, segmentectomy with radiofrequency ablation – 7, segmentectomy with cryoablation – 3, segmentectomy with radiofrequency ablation and cryoablation – 3. Also, hemihepatectomy was performed in 15 patients, extended hemihepatectomy – 13, hemihepatectomy with radiofrequency ablation – 1. Radiofrequency ablation and cryoablation were performed in 8 cases, transarterial chemoembolization in 12 cases. The average age of the patients was 56.3 ± 3 years. All patients subsequently underwent adjuvant chemotherapy. In 9 case the regional chemoembolization was added.
Results. Postoperative morbidity was 30 cases (34.5%) in the immediate postoperative period. Actuarial survival in the patients undergoing surgery was 1 year – 63%, 3 years – 34% and 5 years – 28%.
Conclusion. A differentiated approach in local destruction of colorectal liver metastases allows satisfactory long-term results in multiple bilobar lesions. The key to success is a multidisciplinary approach to treatment.
About the Authors
A. V. ChzhaoRussian Federation
Doct. of Sci. (Med.), Professor, Deputy Director
27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
V. A. Vishnevsky
Russian Federation
Doct. of Sci. (Med.), Professor
27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
D. A. Ionkin
Russian Federation
Cand. of Sci. (Med.), Surgeon of the Oncology Department
27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
A. A. Olifir
Russian Federation
Graduate Student of the Oncology Department
27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
Phone: 8-926-369-31-76
X. A. Ayvazyan
Russian Federation
Resident of the Oncology Department
27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
Yu. A. Kovalenko
Russian Federation
Cand. of Sci. (Med.), Senior Researcher of the Oncology Department
27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
O. I. Zhavoronkova
Russian Federation
Cand. of Sci. (Med.), Functional Diagnostics Physician
27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
Yu. A. Stepanova
Russian Federation
Doct. of Sci. (Med.), Senior Researcher, Physician of the Ultrasound Diagnostics Department
27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
N. A. Karelskaya
Russian Federation
Cand. of Sci. (Med.), Physician of the Department of Radiology and Magnetic Resonance Imaging
27, Bol'shaya Serpukhovskaia str., Moscow, 117997, Russian Federation
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Review
For citations:
Chzhao A.V., Vishnevsky V.A., Ionkin D.A., Olifir A.A., Ayvazyan X.A., Kovalenko Yu.A., Zhavoronkova O.I., Stepanova Yu.A., Karelskaya N.A. The choice of local destruction method of colorectal cancer liver metastases. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2019;24(4):30-36. (In Russ.) https://doi.org/10.16931/1995-5464.2019430-36