Preview

Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery

Advanced search

Comparative assessment of the short-term and long-term results of traditional and original ways of terminoterminal pancreatojejunostomy at a subtotal resection of a head of a pancreas

https://doi.org/10.16931/1995-5464.2020138-47

Abstract

Aim. Compare the short-term and long-term results of the traditional and original methods of terminoterminal pancreaticojejunostomy with subtotal resection of the pancreatic head.

Materials and methods. The results of subtotal resection of the pancreatic head in 20 patients with chronic pancreatitis with pancreatic duct obstruction at the level of the head are analyzed. In 10 cases at the final stage of the operation, the traditional terminoterminal pancreaticojejunostomy was performed, in 10 – in the original way.

Results. Biliary tract decompression was performed in 65% of patients. The average duration of operation from original terminoterminal pancreaticojejunostomy operation was 170 min. [165; 180], intraoperative blood loss – 210 ml [200; 240], the average duration of postoperative hospital stay – 16 days [14; 17]; there were no mortality. After 5 years, in all patients who underwent the original terminoterminal pancreaticojejunostomy, the expressiveness of pain according to the developed ten-point scale was <4 points. Frequency for the first time diagnosed diabetes was 50–60%. The need for enzyme drugs was noted in 37.5–40% of cases. The frequency of complications requiring repeated surgical interventions is 12%, persistent disability – 50%. The quality of life indicators for Medical Outcome Study Short Form-36 and European Organisation for Research and Treatment of Cancer quality of life questionnaire – C30 exceeded those of the traditional method of completing the surgery by 3.9–8.4% and 9.3–16.7%.

Conclusion. The original way of a single-row terminoterminal pancreaticojejunostomy with subtotal resection of the pancreatic head allows to reduce averages operative time and postoperative hospital stay. The risk of hemorrhagic complications from the resected pancreatic head does not decrease (10%). After 5 years, an insignificant advantage of the original method of terminoterminal pancreaticojejunostomy compared with the traditional one was noted. The incidence of permanent disability was 15% less, the quality of life indicators for the Medical Outcome Study Short Form-36 and European Organisation for Research and Treatment of Cancer quality of life questionnaire – C30 were better.

About the Authors

A. R. Propp
Omsk Region “Regional Clinical Hospital”; Omsk State Medical University, Department of Hospital Surgery
Russian Federation

Aleksandr R. Propp – Cand. of Sci. (Med.), Assistant of the Department of Hospital Surgery

3, Berezovay str., Omsk, 644033, Russian Federation

12, Lenina str., Omsk, 644099, Russian Federation



E. N. Degovtsov
Omsk State Medical University, Department of Hospital Surgery
Russian Federation

Doct. of Sci. (Med.), Associate Professor, Head of the Department of Hospital Surgery

12, Lenina str., Omsk, 644099, Russian Federation



S. A. Nikulina
Omsk Region “Regional Clinical Hospital”
Russian Federation

Surgeon of the Surgical Department

3, Berezovay str., Omsk, 644033, Russian Federation



References

1. Ni Q., Yun L., Roy M., Shang D. Advances in surgical treatment of chronic pancreatitis. World J. Surg. Oncol. 2015; 13: 34. https://doi.org/10.1186/s12957-014-0430-4.

2. Forsmark C.E. Pancreatitis and its complications. United States of America: Humana Press, 2005. 338 p.

3. Sabater L., Ausania F., Bakker O.J., Boadas J., Domínguez- Muñoz J.E., Falconi M., Fernández-Cruz L., Frulloni L., González-Sánchez V., Lariño-Noia J., Lindkvist B., Lluís F., Morera-Ocón F., Martín-Pérez E., Marra-López C., Moya- Herraiz Á., Neoptolemos J.P., Pascual I., Pérez-Aisa Á., Pezzilli R., Ramia J.M., Sánchez B., Molero X., Ruiz-Montesinos I., Vaquero E.C., de-Madaria E. Evidence-based guidelines for the management of exocrine pancreatic insufficiency after pancreatic surgery. Ann. Surg. 2016; 264 (6): 949–958. https://doi.org/10.1097/SLA.0000000000001732.

4. Drewes A.M., Bouwense S.A.W., Campbell C., Ceyhan G.O., Delhaye M., Demir I.E., Garg P.K., Goor H., Halloran C., Isaji S., Neoptolemos J.P., Olesen S.S., Palermo T., Pasricha P.J., Sheel A., Shimosegawa T., Szigethy E., Whitcomb D.C., Yadav D. Guidelines for the understanding and management of pain in chronic. Working group for the International (IAP e APA e JPS e EPC) Consensus Guidelines for Chronic Pancreatitis. Pancreatology. 2017; 17 (5): 720–731. https://doi.org/10.1016/j.pan.2017.07.006.

5. Olesen S.S., Juel J., Nielsen A.K., Frøkjær J.B., Wilder- Smith O.H., Drewes A.M. Pain severity reduces life quality in chronic pancreatitis: implications for design of future outcome trials. Pancreatology. 2014; 14 (6): 497–502. https://doi.org/10.1016/j.pan.2014.09.009.

6. Jha A.K., Goenka M.K., Goenka U. Chronic pancreatitis in Eastern India: Experience from a tertiary care center. Indian J. Gastroenterol. 2017; 36 (2): 131–136. https://doi.org/10.1007/s12664-017-0733-9.

7. Jawad Z.A.R., Kyriakides C., Pai M., Wadsworth C., Westaby D., Vlavianos P., Jiao L.R. Surgery remains the best option for the management of pain in patients with chronic pancreatitis: A systematic review and meta-analysis. Asian J. Surg. 2017; 40 (3): 179–185. https://doi.org/10.1016/j.asjsur.2015.09.005.

8. Plagemann S., Welte M., Izbicki J.R., Bachmann K. Surgical treatment for chronic pancreatitis: past, present, and future. Gastroenterol. Res. Prac. 2017; 2017: 8418372. https://doi.org/10.1155/2017/8418372.

9. Egorov V.I., Vishnevskiy V.A., Shastny A.T., Shevchenko T.V., Zhavoronkova O.I., Petrov R.V., Poltoracky M.V., Melekhina O.V. Pancreatic head resection in chronic pancreatitis. How to do and how to call? (analytical review). Pirogov Russian Journal of Surgery = Khirurgiya. Zhurnal imeni N.I. Pirogova. 2009; 8: 57–66. (In Russian)

10. Kleeff J., Stöß C., Mayerle J., Stecher L., Maak M., Simon P., Nitsche U., Friess H. Evidence-based surgical treatments for chronic pancreatitis. Dtsch Arztebl. Int. 2016; 113: 489–496. https://doi.org/10.3238/arztebl.2016.0489.

11. Farkas G., Leindler L., Daróczi M., Farkas G. Jr. Organ-preserving pancreatic head resection in chronic pancreatitis. Br. J. Surg. 2003; 90 (1): 29–32. https://doi.org/10.1002/bjs.4016.

12. Vellaisamy R., Ramalingam Durai Rajan S., Jesudasan J., Anbalagan A., Duraisamy B., Raju P., Servarayan Murugesan C., Devy Gounder K. Single layer anastomosis for pancreatico jejunostomies (PJ) for chronic calcific pancreatitis. HPB. 2016; 18 (1): 439. https://doi.org/10.1016/j.hpb.2016.03.152.

13. Hirono S., Kawai M., Okada K., Miyazawa M., Kitahata Y., Hayami S., Ueno M., Yamaue H. Modified blumgart mattress suture versus conventional interrupted suture in pancreaticojejunostomy during pancreaticoduodenectomy. Ann. Surg. 2019; 269 (2): 243–251. https://doi.org/10.1097/SLA.0000000000002802.

14. Bannone E., Andrianello S., Marchegiani G., Masini G., Malleo G., Bassi C., Salvia R. Postoperative acute pancreatitis following pancreaticoduodenectomy a determinant of fistula potentially driven by the intraoperative fluid management. Ann. Surg. 2018; 268 (5): 815–822. https://doi.org/10.1097/SLA.0000000000002900.

15. Halle-Smith J.M., Vinuela E., Brown R.M., Hodson J., Zia Z., Bramhall S.R., Marudanayagam R., Sutcliffe R.P., Mirza D.F., Muiesan P., Isaac J., Roberts K.J. A comparative study of risk factors for pancreatic fistula after pancreatoduodenectomy or distal pancreatectomy. HPB. 2017; 19 (8): 727–734. https://doi.org/10.1016/j.hpb.2017.04.013.

16. Fu S.J., Shen S.L., Li S.Q., Hu W.J., Hua Y.P., Kuang M., Liang L.J., Peng B.G. Risk factors and outcomes of postoperative pancreatic fistula after pancreatico-duodenectomy: an audit of 532 consecutive cases. BMC Surg. 2015; 15: 34. https://doi.org/10.1186/s12893-015-0011-7.

17. Galperin E.I. Classification of chronic pancreatitis: determination of severity, the choice of treatment method and the necessary operation. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2013; 18 (4): 83–93. (In Russian)

18. Steshenko A.A. Quality of life assessment using the EORTC QLQ-C30, EORTC QLQ-PAN28 questionnaires in patients with chronic pancreatitis after surgical treatment. Aktualnye problemy sovremennoj mediciny: Vestnik ukrainskoj medikostomatologicheskoj akademii. 2013; 44 (13): 58–63. (In Russian)

19. Diener M.K., Hüttner F.J., Kieser M., Knebel P., Dörr- Harim C., Distler M., Grützmann R., Wittel U.A., Schirren R., Hau H.M., Kleespies A., Heidecke C.D., Tomazic A., Halloran C.M., Wilhelm T.J., Bahra M., Beckurts T., Börner T., Glanemann M., Steger U., Treitschke F., Staib L., Thelen K., Bruckner T., Mihaljevic A.L., Werner J., Ulrich A., Hackert T., Büchler M.W. Partial pancreatoduodenectomy versus duo denum- preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet. 2017; 390 (10099): 1027–1037. https://doi.org/10.1016/S0140-6736(17)31960-8.

20. Propp A.R., Poluektov V.L, Nikulinа S.A Мethod of pancreatojejunostomy with subtotal resection of the pancreatic head. Pirogov Russian Journal of Surgery = Khirurgiya. Zhurnal imeni N.I. Pirogova. 2015; 6: 74–77. (In Russian)

21. D‘Haese J.G., Cahen D.L., Werner J. Current surgical treatment options in chronic pancreatitis. Pancreapedia. Exocrine Pancreas Knowledge Base. 2016. https://doi.org/10.3998/panc.2016.26.

22. Takayuki A., Uchida E., Nakamura Y., Yamahatsu K., Matsushita A., Katsuno A., Cho K., Kawamoto M. Current surgical treatment for chronic pancreatitis. J. Nippon Med. Sch. 2011; 78 (6): 355. https://pdfs.semanticscholar.org/81de/ad7adae05dda251e97f3687ff310ea177a43.pdf.

23. Ke N., Jia D., Huang W., Nunes Q.M., Windsor J.A., Liu X., Sutton R. Earlier surgery improves outcomes from painful chronic pancreatitis. Medicine (Baltimore). 2018; 97 (19): 1–7. https://doi.org/10.1097/MD.0000000000010651.

24. Zheng Z., Xiang G., Tan C., Zhang H., Liu B., Gong J., Mai G., Liu X. Pancreaticoduodenectomy versus duodenum-preserving pancreatic head resection for the treatment of chronic pancreatitis. Pancreas. 2012; 41 (1): 147–152. https://doi.org/10.1097/MPA.0b013e318221c91b.

25. Jawad Z.A.R., Tsim N., Pai M., Bansi D., Westaby D., Vlavianos P., Jiao L.R. Short and long-term post-operative outcomes of duodenum preserving pancreatic head resection for chronic pancreatitis affecting the head of pancreas: a systematic review and meta-analysis. HPB. 2016; 18 (2): 121–128. https://doi.org/10.1016/j.hpb.2015.10.003.

26. Gurusamy K.S., Lusuku C., Halkias C., Davidson B.R. Duodeum- preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis. Cochrane Database Syst. Rev. 2016; 2: CD011521. https://doi.org/10.1002/14651858.CD011521.pub2.

27. Klaiber U., Alldinger I., Probst P., Bruckner T., Contin P., Köninger J., Hackert T., Büchler M.W., Diener M.K. Duodenum- preserving pancreatic head resection: 10-year follow-up of a randomized controlled trial comparing the Beger procedure with the Berne modification. Surgery. 2016; 160 (1): 127–135. https://doi.org/10.1016/j.surg.2016.02.028.

28. Beger H.G., Warshaw A.L., Hruban R.H., Buchler M.W., Lerch M.M., Neoptolemos J.P., Shimosegawa T., Whitcomb D.C. The pancreas: an integrated textbook of basic science, medicine, and surgery. 3rd edition. Wiley-Blackwell, 2018. 1216 p.


Review

For citations:


Propp A.R., Degovtsov E.N., Nikulina S.A. Comparative assessment of the short-term and long-term results of traditional and original ways of terminoterminal pancreatojejunostomy at a subtotal resection of a head of a pancreas. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2020;25(1):38-47. (In Russ.) https://doi.org/10.16931/1995-5464.2020138-47

Views: 643


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1995-5464 (Print)
ISSN 2408-9524 (Online)