Особенности применения модифицированных критериев оценки ответа на лечение солидных опухолей у пациентов с гепатоцеллюлярной карциномой

В статье освещены основные подходы к применению модифицированных критериев оценки ответа солидных опухолей у пациентов с гепатоцеллюлярной карциномой, отражены особенности и преимущества таких критериев. Согласно mRECIST полный ответ означает исчезновение любого внутриопухолевого артериального усиления во всех таргетных очагах. Частичный ответ означает уменьшение на ≥30% наибольших размеров жизнеспособной опухоли в таргетных очагах по сравнению с исходной суммой наибольших размеров жизнеспособной опухоли в них. Прогрессирование заболевания означает увеличение на ≥20% суммы наибольших диаметров жизнеспособной опухоли в таргетных очагах по сравнению с надиром. Стабилизацию заболевания определяют, если полученные данные не являются частичным ответом или прогрессированием.

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