Extracorporeal resections and autotransplantation of the liver: an experience of 4 clinical cases
https://doi.org/10.16931/1995-5464.2018445-53
- Р Р‡.МессенРТвЂВВВВВВВВжер
- РћРТвЂВВВВВВВВнокласснРСвЂВВВВВВВВРєРСвЂВВВВВВВВ
- LiveJournal
- Telegram
- ВКонтакте
- РЎРєРѕРїРСвЂВВВВВВВВровать ссылку
Full Text:
Abstract
Aim. To evaluate short-term outcomes of ex situ, ex vivo liver resection in patients with lesion of liver veins confluence and inferior vena cava who were undesirable for conventional liver resection.
Matherial and methods. There were 4 procedures of ex situ liver resection and autotransplantation without veno-venous bypass.
Results. Postoperative complications developed in all cases, complications grade IIIa and over — in 50% of patients. Three patients are alive without signs of disease, follow-up ranged from 8 months to 2 years. One patient died after surgery.
Conclusion. Comprehensive planning of such procedures is a key for good early and long-term postoperative outcomes. It is strongly recommended to perform liver autotransplantation in well experienced specialize center due to difficult and traumatic surgery.
About the Authors
M. S. NovruzbekovRussian Federation
Murad S. Novruzbekov — Cand. of Med. Sci., Head of the Research Department of Liver Transplantation.
3, Bolshaya Sukharevskaya, Moscow, 129090, Phone: 8-495-628-35-02
V. A. Gulyaev
Russian Federation
Vladimir A. Gulyaev — Doct. of Med. Sci., Leading Research Fellow of the Department of Kidney and Pancreas Transplantation.
3, Bolshaya Sukharevskaya, Moscow, 129090
O. D. Olisov
Russian Federation
Oleg D. Olisov — Cand. of Med. Sci., Senior Research Fellow of the Department of Liver Transplantation.
3, Bolshaya Sukharevskaya, Moscow, 129090
K. N. Lutsyk
Russian Federation
Konstantin N. Lutsyk — Cand. of Med. Sci., Head of the Department of Liver Transplantation.
3, Bolshaya Sukharevskaya, Moscow, 129090
R. B. Akhmetshin
Russian Federation
Ravil B. Akhmetshin — Surgeon of the Department of Kidney and Pancreas Transplantation.
3, Bolshaya Sukharevskaya, Moscow, 129090
K. M. Magomedov
Russian Federation
Kubay M. Magomedov — Surgeon of the Department of Kidney and Pancreas Transplantation.
3, Bolshaya Sukharevskaya, Moscow, 129090
B. I. Kazimov
Russian Federation
Bakhtiyar I. Kazymov — Surgeon of the Department of Kidney and Pancreas Transplantation.
3, Bolshaya Sukharevskaya, Moscow, 129090
L. V. Donova
Russian Federation
Lubov V. Donova — Cand. of Med. Sci., Senior Research Fellow of the Department of Liver Transplantation.
3, Bolshaya Sukharevskaya, Moscow, 129090R. Sh. Muslimov
Rustam S. Muslimov — Cand. of Med. Sci., Leading Research Fellow of the CT Diagnosis Department.
3, Bolshaya Sukharevskaya, Moscow, 129090References
1. Mehrabi A., Fonouni H., Golriz M., Hofer S., Hafezi M., Rahbari N.N., Weitz J., Buchler M.W., Schmidt J. Hypothermic ante situm resection in tumors of the hepatocaval confluence. Dig. Surg. 2011; 28 (2): 100-108. https://doi.org/10.1159/000323818.
2. Pichlmayr R., Grosse H., Hauss J., Gubernatis G., Lamesch P., Bretschneider H.J. Technique and preliminary results of extracorporeal liver surgery (bench procedure) and surgery on the in situ perfused liver. Br. J. Surg. 1990; 77 (1): 21-26.
3. Severtsev A.N., Nikolaenko E.M., Brekhov E.I., Shchup-lova E.N., Bogdanov A.E., Petruk E.V., Repin I.G., Khokhlov A.V. Autologous liver transplantation for focal hepatic lesions. Khirurgiia(Mosk). 2002; (1): 52-58. (In Russian)
4. Voskanyan S.E., Artemiev A.I., Naydenov E.V., Zabezhin-sky D.A., Chuchuev E.S., Rudakov V.S., Shabalin M.V., Shcherbin V.V. Transplantation technologies for surgical treatment of locally advanced liver alveococcosis with great vessels invasion. Annaly khirurgicheskoy gepatologii = Annals of HPB surgery. 2016; 21 (2): 25-31. https://doi.org/10.16931/1995-5464.2016225-31. (In Russian)
5. Porshennikov I.A., Bykov A.Yu., Pavlik V.N., Kartashov A.S., Shchekina E.E., Korobeynikova M.A., Yushina E.G. Liver transplantation and resection with vascular reconstruction for advanced alveococcosis. Annaly khirurgicheskoy gepatologii = Annals of HPB surgery. 2016; 21 (2): 11-24. https://doi.org/10.16931/1995-5464.2016211-24. (In Russian)
6. McGilvray I., Hemming A. In Blumgart’s Surgery of the Liver, Biliary tract and Pancreas, 6th Edition, Elsevier, 2017; 2: 16701679.
7. Yamamoto Y. Antesitum hepatic resection for tumors involving the confluence of hepatic veins and IVC. J. HBP Sci. 2013; 20 (3): 313-323. https://doi.org/10.1007/s00534-012-0525-7.
8. Wang F.Q., Lu Q., Yan J., Peng Y.Y., Xie C.R., Su Y.J., Zhou J.Y., Wang B.L., Zhao W.X., Wang X.M., Bie P., Yin Z.Y. Ex vivo hepatectomy and partial liver autotransplantation for hepatoid adenocarcinoma: A case report. Oncol. Lett. 2015; 9 (5): 2199-2204. https://doi.org/10.3892/ol.2015.3041.
9. Zhang K.M., Hu X.W., Dong J.H., Hong Z.X., Wang Z.H., Li G.H., Qi R.Z., Duan W.D., Zhang S.G. Ex-situ liver surgery without veno-venous bypass. World J. Gastroenterol. 2012; 18 (48): 7290-7295. https://doi.org/10.3748/wjg.v18.i48.7290.
10. Vicente E., Quijano Y., Ielpo B., Duran H., Diaz E., Fabra I., Malave L., Ferri V., Lazzaro S., Kalivaci D., Caruso R. Ex situ hepatectomy and liver autotransplantation for cholangiocarcinoma. Ann. Surg. Oncol. 2017; 24 (13): 3990. https://doi.org/10.1245/s10434-017-6104-z.
11. Tuxun T., Aini A., Li Y.P., Apaer S., Zhang H., Li T, Aji T., Yimiti Y., Zhao J.M., Shao Y.M., Wen H. Systematic review and meta-analysis of feasibility, safety, and efficacy of ex situ liver resection and autotransplantation. Zhonghua Yi Xue Za Zhi. 2016; 96 (28): 2251-2257. https://doi.org/10.3760/cma.j.issn.0376-2491.2016.28.011.
12. Ye Q., Senninger N. The consensus on liver autotransplantation from an international panel of experts. Hepatobiliary Pancreat. Dis. Int. 2017; 16 (1): 10-16. https://doi.org/10.1016/S1499-3872(16)60175-3.
Review
For citations:
Novruzbekov M.S., Gulyaev V.A., Olisov O.D., Lutsyk K.N., Akhmetshin R.B., Magomedov K.M., Kazimov B.I., Donova L.V., Muslimov R.Sh. Extracorporeal resections and autotransplantation of the liver: an experience of 4 clinical cases. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2018;23(4):45-53. (In Russ.) https://doi.org/10.16931/1995-5464.2018445-53
ISSN 2408-9524 (Online)